Simvastatin but not pravastatin inhibits the proliferation of rat aorta myocytes

Regulation of the mevalonate pathway

1990 • 5,282 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation.

1986 • 1,644 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.

1980 • 1,195 citations

HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia

1988 • 760 citations

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

1986 • 376 citations

Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1980 • 353 citations

Inhibition of rat arterial smooth muscle cell proliferation by heparin. II. In vitro studies.

1980 • 337 citations

An endothelial cell-derived growth factor.

1980 • 316 citations

Essential role for mevalonate synthesis in DNA replication

1979 • 297 citations

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 4. Side-chain ester derivatives of mevinolin

1986 • 261 citations

Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A Reductase

1978 • 252 citations

The dual role of mevalonate in the cell cycle.

1983 • 201 citations

Tissue selectivity of the cholesterol-lowering agents lovastatin, simvastatin and pravastatin in rats in vivo

1989 • 172 citations

Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

1990 • 171 citations

Regulation of Smooth Muscle Cell Growth in Injured Artery

1989 • 167 citations

Control of proliferation of bovine vascular endothelial cells

1977 • 139 citations

Tissue-selective acute effects of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase on cholesterol biosynthesis in lens.

1989 • 105 citations

Preventive effect of pravastatin sodium, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on coronary atherosclerosis and xanthoma in WHHL rabbits

1988 • 103 citations

Role of cholesterol metabolism in cell growth.

1984 • 70 citations

Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low

1990 • 59 citations

Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits.

1989 • 58 citations

Growth of cultured cells from patients with Fanconi anemia

1976 • 45 citations

Isolation and characterization of revertant cell lines. II. Growth control of a polyploid revertant line derived from SV40‐transformed 3T3 mouse cells

1973 • 43 citations

Effects of a Competitive Inhibitor (Mevinolin) of 3‐Hydroxy‐3‐methylglutaryl Coenzyme A Reductase on Human and Bovine Endothelial Cells, Fibroblasts and Smooth Muscle Cells in Vitro

1989 • 39 citations

Comparative effects of simvastatin (MK-733) and pravastatin (CS-514) on hypercholesterolemia induced by cholesterol feeding in rabbits

1990 • 36 citations

In vitro inhibition of arterial myocyte growth and stimulation of low density lipoprotein metabolism by SIM 6080, a new calcium antagonist

1990 • 14 citations