Free radical modification of prosthetic heme groups

Cytochrome P-450: Structure, Mechanism, and Biochemistry

1986 • 2,703 citations

Cytochrome P-450

1986 • 734 citations

Free-radical and molecule thermochemistry from studies of gas-phase iodine-atom reactions

1969 • 321 citations

Inhibition of Cytochrome P450 Enzymes

2015 • 258 citations

Protein control of prosthetic heme reactivity. Reaction of substrates with the heme edge of horseradish peroxidase.

1987 • 216 citations

Homopolar‐ and Heteropolar Bond Dissociation Energies and Heats of Formation of Radicals and Ions in the Gas Phase. I. Data on organic molecules

1973 • 214 citations

Reaction of myoglobin with phenylhydrazine: a molecular doorstop

1984 • 190 citations

The mechanism of olefin epoxidation by oxo-iron porphyrins. Direct observation of an intermediate

1986 • 189 citations

Sulfheme Proteins

1971 • 189 citations

Reactions of the Protein Radical in Peroxide-treated Myoglobin

1989 • 183 citations

The catalytic mechanism of cytochrome P-450. Spin-trapping evidence for one-electron substrate oxidation.

1982 • 182 citations

The myoglobin protein radical. Coupling of Tyr-103 to Tyr-151 in the H2O2-mediated cross-linking of sperm whale myoglobin.

1988 • 180 citations

Epoxidation of olefins by cytochrome P-450 model compounds: kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity

1985 • 174 citations

Relations Between Structure and Reactivity in Free-Radical Chemistry

1970 • 168 citations

Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism , , , ,

1980 • 165 citations

Directive Effects in the Attack of Phenyl Radicals on Carbon-Hydrogen Bonds

1963 • 161 citations

N-Phenylprotoporphyrin IX formation in the hemoglobin-phenylhydrazine reaction. Evidence for a protein-stabilized iron-phenyl intermediate.

1982 • 153 citations

The mechanism of oxidation of nitroalkanes by horseradish peroxidase.

1983 • 142 citations

Mechanism-based inactivation of horseradish peroxidase by sodium azide. Formation of meso-azidoprotoporphyrin IX

1988 • 141 citations

Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase

1978 • 139 citations

Sulfate anion free radical formation by the peroxidation of (Bi) sulfite and its reaction with hydroxyl radical scavengers

1988 • 134 citations

Oxygen Activation and Transfer

1986 • 133 citations

Characterization of the enzymic and nonenzymic peroxidative degradation of iron porphyrins and cytochrome P-450 heme

1985 • 131 citations

Detection of peroxyl and alkoxyl radicals produced by reaction of hydroperoxides with rat liver microsomal fractions

1989 • 130 citations

Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 5. Epoxidation of alkenes catalyzed by a sterically hindered (meso-tetrakis(2,6-dibromophenyl)porphinato)iron(III) chloride

1989 • 128 citations

Structure-mechanism relationships in hemoproteins. Oxygenations catalyzed by chloroperoxidase and horseradish peroxidase.

1987 • 128 citations

Oxygenated form of heme . heme oxygenase complex and requirement for second electron to initiate heme degradation from the oxygenated complex.

1980 • 127 citations

Structure and catalytic mechanism of horseradish peroxidase. Regiospecific meso alkylation of the prosthetic heme group by alkylhydrazines.

1987 • 125 citations

Enzymatic activation of hydrazine derivatives. A spin-trapping study.

1983 • 123 citations

The formation and properties of sulphmyoglobin and sulphcatalase

1961 • 120 citations

Enzymic degradation of heme. Oxygenative cleavage requiring cytochrome P-450

1972 • 120 citations

Polar effects in free-radical reactions. Rate constants in phenylation and new methods of selective alkylation of heteroaromatic bases

1986 • 119 citations

Spin trapping of the azidyl radical in azide/catalase/H2O2 and various azide/peroxidase/H2O2 peroxidizing systems.

1985 • 117 citations

THE CHEMISTRY OF PORPHYRIN π‐CATIONS*

1973 • 116 citations

Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins: implications to the biological epoxidation of olefins by cytochrome P-450

1985 • 115 citations

The mechanism of chloroform and carbon monoxide formation from carbon tetrachloride by microsomal cytochrome P-450

1980 • 114 citations

N-Alkylprotoporphyrin IX formation in 3,5-dicarbethoxy-1,4-dihydrocollidine-treated rats. Transfer of the alkyl group from the substrate to the porphyrin.

1981 • 106 citations

Nucleophilic character of the alkyl radicals. 16. Absolute rate constants and the reactivity-selectivity relationship in the homolytic aromatic alkylation

1977 • 106 citations

Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro

1973 • 105 citations

The reduction of polyhalogenated methanes by liver microsomal cytochrome P450.

1977 • 104 citations

Amino acid free radicals in oxidised metmyoglobin

1967 • 98 citations

Phenyl radical production during the oxidation of phenylhydrazine and in phenylphydrazine‐induced haemolysis

1981 • 97 citations

Model reactions related to cytochrome P-450. Effects of alkene structure on the rates of epoxide formation

1988 • 97 citations

Carbon radicals in the metabolism of alkyl hydrazines.

1983 • 94 citations

Hydrogen-deuterium exchange during propylene epoxidation by cytochrome P-450

1986 • 92 citations

The meso-reactivity of porphyrins and related compounds. Part V. The meso-oxidation of metalloporphyrins

1972 • 87 citations

Oxidation-reduction mechanisms. Inner-sphere and outer-sphere electron transfer in the reduction of iron(III), ruthenium(III), and osmium(III) complexes by alkyl radicals

1982 • 86 citations

Is a linear relationship between the free energies of activation and one-electron oxidation potential evidence for one-electron transfer being rate determining? Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 4. Epoxidation of a series of alkenes by oxo(meso-tetrakis(2,6-dibromophenyl)porphinato)chromium(V)

1989 • 82 citations

Novel meso-substitution reactions of metalloporphyrins

1979 • 82 citations

Oixidation of heme proteins by alkyl halides

1973 • 80 citations

Inactivation of catalase by phenylhydrazine. Formation of a stable aryl-iron heme complex.

1983 • 79 citations

Stereochemistry of cytochrome P-450-catalyzed epoxidation and prosthetic heme alkylation.

1983 • 79 citations

Covalent bonding of the prosthetic heme to protein: a potential mechanism for the suicide inactivation or activation of hemoproteins

1989 • 79 citations

The reaction of phenylhydrazine with microsomal cytochrome P-450. Catalysis of heme modification.

1982 • 77 citations

Studies on Horseradish Peroxidase. XII. A Kinetic Study of the Oxidation of Sulfite and Nitrite by Compounds I and II

1973 • 76 citations

Multiple wavelength analysis of the reaction between hydrogen peroxide and metmyoglobin

1974 • 74 citations

N-Methylprotoporphyrin IX: chemical synthesis and identification as the green pigment produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine treatment.

1981 • 74 citations

The conversion of horseradish peroxidase C to a verdohemoprotein by a hydroperoxide derived enzymatically from indole-3-acetic acid and by m-nitroperoxybenzoic acid.

1980 • 73 citations

Electron spin resonance spectrum of Tyr-151 free radical formed in reactions of sperm whale metmyoglobin with ethyl hydroperoxide and potassium irridate

1989 • 73 citations

The step of carbon monoxide liberation in the sequence of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system.

1982 • 72 citations

Mechanism of induction of haemolytic anaemia by phenylhydrazine

1975 • 71 citations

Self-catalysed, O2-independent inactivation of nadph- or dithionite-reduced microsomal cytochrome P-450 by carbon tetrachloride

1981 • 70 citations

Epoxidation of olefins by cytochrome P-450 model compounds: mechanism of oxygen atom transfer.

1984 • 70 citations

Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 2. Use of the trans-2,trans-3-diphenylcyclopropyl substituent in a search for radical intermediates

1988 • 70 citations

Spin trapping of free radical products of CCI₄ activation using pulse radiolysis and high energy radiation procedures

1980 • 70 citations

Formation, crystal structure, and rearrangement of a cytochrome P-450cam iron-phenyl complex

1990 • 70 citations

Sulfheme Proteins

1972 • 68 citations

Spin-trapping of free radicals formed during microsomal metabolism of ethylhydrazine and acetylhydrazine

1981 • 68 citations

Reactivity of polycyclic aromatic aryl radicals

1989 • 68 citations

Formation of N-phenylheme in the hemolytic reaction of phenylhydrazine with hemoglobin

1981 • 65 citations

Reactions of iron porphyrins with methyl radicals

1981 • 65 citations

Electrochemistry and spectroelectrochemistry of .sigma.-bonded iron aryl porphyrins. 1. Evidence for reversible aryl migration from iron to nitrogen of five-coordinate complexes

1984 • 65 citations

Control of reactivity at the porphyrin periphery by metal ion co-ordination: a general method for specific nitration at the β-pyrrolic position of 5,10,15,20-tetra-arylporphyrins

1984 • 64 citations

Mechanisms of electron transfer from sulfite to horseradish peroxidase-hydroperoxide compounds

1976 • 63 citations

Oxidation of substituted alkyl radicals by hexachloroiridate(2-), hexacyanoferrate(3-), and permanganate ions in aqueous solution. Electron transfer versus chlorine transfer from hexachloroiridate(2-) ion

1982 • 63 citations

A STUDY OF SULFHEMOGLOBIN

1938 • 62 citations

Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2, 6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts

1987 • 61 citations

A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase.

1982 • 61 citations

Transient formation of N-alkylhemins during hemin-catalyzed epoxidation of norbornene. Evidence concerning the mechanism of epoxidation

1987 • 61 citations

Suicide inactivation of cytochrome P-450 model compounds by terminal olefins. 2. Steric and electronic effects in heme N-alkylation and epoxidation

1990 • 61 citations

Formation of a .sigma.-bonded aryliron complex in the reaction of arylhydrazines with hemoglobin and myoglobin

1983 • 60 citations

Reactions of radicals. 41. Reactivity patterns of the methyl radical

1972 • 58 citations

Reactions of ferryl lactoperoxidase (compound II) with sulfide and sulfhydryl compounds.

1984 • 57 citations

Mechanism of inhibition of horseradish peroxidase by cyclopropanone hydrate.

1982 • 57 citations

Formation and Metabolism of Bile Pigments in Vivo

1979 • 57 citations

The structure of the chromophore of sulphymyoglobin

1967 • 56 citations

Identification of N-methylprotoporphyrin IX in livers of untreated mice and mice treated with 3,5-diethoxycarbonyl-1,4-dihydrocollidine: Source of the methyl group

1981 • 52 citations

Suicide inactivation of cytochrome P-450 model compounds by terminal olefins. 1. A mechanistic study of heme N-alkylation and epoxidation

1990 • 52 citations

Stereospecific haem cleavage. A model for the formation of bile-pigment isomers in vivo and in vitro

1976 • 51 citations

Sulfheme Proteins

1972 • 50 citations

Liver production of N‐alkylated porphyrins caused in mice by treatment with substituted dihydropyridines

1981 • 50 citations

The effect of spin traps on phenylhydrazine-induced haemolysis

1983 • 50 citations

beta-meso-Phenylbiliverdin IX alpha and N-phenylprotoporphyrin IX, products of the reaction of phenylhydrazine with oxyhemoproteins.

1981 • 50 citations

Resonance Raman Spectra of Bovine Liver Catalase Compound II

1989 • 49 citations

Inactivation of cytochrome P-450 during catalytic oxidation of a 3-[(arylthio)ethyl]sydnone: N-vinyl heme formation via insertion into the iron-nitrogen bond

1986 • 48 citations

Carbon tetrachloride and 2-isopropyl-4-pentenamide-induced inactivation of cytochrome P-450 leads to heme-derived protein adducts

1986 • 48 citations

Spectroscopic studies of iron(IV) phenylporphyrin complexes and their conversion into iron(II) N-phenylporphyrins

1986 • 47 citations

The mechanism of cumene hydroperoxide-dependent lipid peroxidation: The function of cytochrome P-450

1986 • 47 citations

Proton NMR characterization of isomeric sulfmyoglobins: preparation, interconversion, reactivity patterns, and structural features

1987 • 46 citations

Structural Characterization of Nitrimyoglobin

1989 • 45 citations

Covalent binding to apoprotein is a major fate of heme in a variety of reactions in which cytochrome P-450 is destroyed

1986 • 45 citations

Reactions of iron(III) porphyrins with peroxyl radicals derived from halothane and halomethanes

1984 • 45 citations

One-electron reduction of ferrideuterioporphyrin IX and reaction of the oxidized and reduced forms with chlorinated methyl radicals

1980 • 44 citations

Substrate oxidation by the heme edge of fungal peroxidases. Reaction of Coprinus macrorhizus peroxidase with hydrazines and sodium azide

1989 • 43 citations

Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implications.

1987 • 43 citations

Hemoprotein destruction. Iron-nitrogen shift of a phenyl group in a porphyrin complex

1982 • 43 citations

Sulfmyoglobin. Resonance Raman spectroscopic evidence for an iron-chlorin prosthetic group.

1984 • 43 citations

The role of peroxide in haem degradation. A study of the oxidation of ferrihaems by hydrogen peroxide

1978 • 43 citations

Reactions of Horseradish Peroxidase with Azide. Evidence for a Methionine Residue at the Active Site^*

1967 • 42 citations

Oxidation of cyanide to the cyanyl radical by peroxidase/H2O2 systems as determined by spin trapping

1988 • 42 citations

4-Alkyl radical extrusion in the cytochrome P-450-catalyzed oxidation of 4-alkyl-1,4-dihydropyridines

1988 • 41 citations

Studies on cytochrome P-450-dependent lipid hydroperoxide reduction

1984 • 41 citations

Ferric isoporphyrins from hydroperoxide oxidation of (tetraphenylporphinato)iron(III) complexes

1984 • 41 citations

Chiral orientation of prosthetic heme in the cytochrome P-450 active site.

1983 • 41 citations

Inactivation of lignin peroxidase by phenylhydrazine and sodium azide

1990 • 40 citations

Reaction of Monosubstituted Hydrazines and Diazenes with Rat‐Liver Cytochrome P450

1983 • 40 citations

Radical intermediates in the epoxidation of alkenes by cytochrome P-450 model systems. The design of a hypersensitive radical probe

1988 • 40 citations

Formation of a ferric carbanion complex from halothane and cytochrome P-450: electron spin resonance, electronic spectra, and model complexes

1984 • 40 citations

Mechanisms of hemin-catalyzed oxidations: rearrangements during the epoxidation of trans-cyclooctene

1986 • 40 citations

Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine.

1982 • 39 citations

Metabolism-based covalent bonding of the heme prosthetic group to its apoprotein during the reductive debromination of BrCCl3 by myoglobin.

1990 • 39 citations

Resonance Raman spectroscopy of metallochlorins: models for green heme protein prosthetic groups

1985 • 39 citations

Loss of haem and haemoproteins during the generation of superoxide anion and hydrogen peroxide: A pathway not involving production of carbon monoxide

1981 • 38 citations

Intermediates in the Reaction between Hydrogen Peroxide and Horseradish Peroxidase.

1971 • 38 citations

Transition state geometry in epoxidation by iron-oxo porphyrin at the compound I oxidation level. Epoxidation of alkenes catalyzed by a sterically hindered meso-tetrakis(2,6-dibromophenyl)porphinato iron(III) chloride

1988 • 37 citations

Nuclear magnetic resonance study of the molecular and electronic structure of the stable green sulfhemin prosthetic groups extracted from sulfmyoglobin

1988 • 37 citations

Inactivation of myoglobin by ortho-substituted arylhydrazines. Formation of prosthetic heme aryl-iron but not N-aryl adducts

1985 • 36 citations

Drug metabolism — from molecules to man

1988 • 36 citations

Bildungsmöglichkeiten und Eigenschaften der Pseudohämoglobine. 14. Mitteilung in der Reihe der Eisenstudien.

1938 • 36 citations

Methene bridge carbon atom elimination in oxidative heme degradation catalyzed by heme oxygenase and NADPH-cytochrome P-450 reductase

1984 • 35 citations

Nitrobenzyl radical metabolites from microsomal reduction of nitrobenzyl chlorides.

1986 • 34 citations

Degradation of cytochrome P-450 haem by carbon tetrachloride and 2-allyl-2-isopropylacetamide in rat liver in vivo and in vitro. Involvement of non-carbon monoxide-forming mechanisms

1979 • 34 citations

Cytochrome P-450 inactivation by 3-alkylsydnones. Mechanistic implications of n-alkyl and n-alkenyl heme adduct formation

1988 • 33 citations

Secobarbital-mediated inactivation of rat liver cytochrome P-450b: a mechanistic reappraisal.

1989 • 33 citations

Structure of a stable form of sulfheme

1986 • 33 citations

Evidence of a hydrazine-reactive group at the active site of the nonheme portion of horseradish peroxidase

1970 • 33 citations

Formation of heme-derived products by the reaction of ferrous deoxymyoglobin with bromotrichloromethane

1989 • 32 citations

The Formation of Green Heme Pigments from Metmyoglobin and Methemoglobin by the Action of Nitrite^*

1964 • 30 citations

Identification of the altered pyrrole in sulfmyoglobin and an extractable sulfhemin: participation of the 4-vinyl group in the saturation of the pyrrole in one form of sulfmyoglobin

1986 • 30 citations

The lipid peroxidation model for halogenated hydrocarbon toxicity. kinetics of peroxyl radical processes involving fatty acids and Fe(III) porphyrins

1985 • 29 citations

Cytochrome P-450 and halothane metabolism. Decrease in rat liver microsomal P-450 in vitro

1983 • 29 citations

Studies on Horseradish Peroxidase. XIII. The Kinetic Effect of Cyanide on the Oxidation–Reduction Cycle

1973 • 28 citations

Transfer of oxygen from percarboxylic acids and alkyl hydroperoxides to (meso-tetraphenylporphinato)cobalt(III) chloride

1986 • 28 citations

On the reaction of methyl and phenyl radicals with p-benzoquinone in aqueous solution

1982 • 27 citations

In vivo formation of σ-methyl- and σ-phenyl-ferric complexes of hemoglobin and liver-cytochrome P-450 upon treatment of rats with methyl- and phenylhydrazine

1986 • 27 citations

Multiple forms of sulfmyoglobin as detected by 1H nuclear magnetic resonance spectroscopy

1986 • 26 citations

Reduction of benzyl halides by liver microsomes

1983 • 26 citations

Kinetic characterization of the inactivation process of two peroxidase isoenzymes in the oxidation of indolyl-3-acetic acid

1989 • 26 citations

Verdohaem and ‘verdoglobins’

1951 • 26 citations

Immunochemical identification of an irreversibly bound heme-derived adduct to cytochrome P-450 following CCl4 treatment of rats

1985 • 25 citations

Covalent binding of carbon tetrachloride metabolites to the heme moiety of cytochrome P-450 and its degradation products.

1982 • 25 citations

Peripheral attack in the reduction and oxidation of iron porphyrins

1969 • 25 citations

Stereochemical and mechanistic studies of the "suicide" event in biomimetic P-450 olefin epoxidation

1986 • 25 citations

Proton NMR spectroscopy of sulfmyoglobin

1985 • 25 citations

One-electron reduction of ferriporphyrins and reactions of ferric and ferrous porphyrins with a halothane-derived radical

1982 • 24 citations

Use of spin traps to elucidate radical mechanisms of oxidations by hydroperoxides catalyzed by hemeproteins

1982 • 24 citations

Radical intermediates in the oxidation of octaethylheme to octaethylverdoheme

1987 • 24 citations

A Spin Trap Study on Anaerobic Dehalogenation of Halothane by a Reconstituted Liver Microsomal Cytochrome P.450 Enzyme System1

1982 • 23 citations

Nitrosation and nitrosylation of haemoproteins and related compounds. Part 1. Porphyrins and metalloporphyrins

1978 • 23 citations

.sigma.-Alkyl iron porphyrins from sterically encumbered alkyl halides and iron(0) porphyrins. Stabilities of the four accessible oxidation states

1989 • 23 citations

Degradation of Rat Hepatic Cytochrome P-450p

1989 • 23 citations

Über die Pentdyopent-Reaktion. - I. Mitteilung

1937 • 23 citations

Mechanism of the initial reaction of phenylhydrazine with oxyhemoglobin and effect of ring substitutions on the bimolecular rate constant of this reaction

1982 • 22 citations

Inactivation of cytochrome p-450 by 2-isopropyl-4- pentenamide and other xenobiotics leads to heme-derived protein adducts

1986 • 22 citations

A possible model of hemoprotein-peroxide complexes formed in an iron-tetraphenylporphyrin system

1986 • 22 citations

EVIDENCE FOR COÖRDINATION OF MONOPHENYL DIIMIDE WITH HEME PROTEINS

1961 • 21 citations

Comparison of the hemoglobin reactions with methyl- and phenyl-hydrazine: Intermediate formation of a hemoglobin Fe(II)-methyldiazene complex

1982 • 20 citations

The degradation of haem by carbon tetrachloride: Metabolic activation requires a free axial coordination site on the haem iron and electron donation

1989 • 19 citations

Reductive metabolism of halothane by purified cytochrome P-450

1988 • 19 citations

The Binding of Trichlorofluoromethane and other Haloalkanes to Cytochrome P-450 under Aerobic and Anaerobic Conditions

1976 • 19 citations

Relative reactivities of carbon-hydrogen bonds in hydrogen atom abstraction by phenyl radicals

1989 • 18 citations

Nitrosation and nitrosylation of haemoproteins and related compounds. Part 3. Attack at the vinyl groups of protoporphyrin dimethyl ester. X-Ray analysis of 81(E)-82-nitroprotoporphyrin dimethyl ester

1980 • 18 citations

The chemistry of N-alkylporphyrin complexes. A comparison of reactivities and structures of chlorozinc(II) complexes of N-benzyl-, N-methyl-, and N-phenyltetraphenylporphyrin

1987 • 17 citations

Free radical intermediates formed during the oxidation of cyanide by horseradish peroxidase/H2O2 as detected with nitroso spin traps

1989 • 16 citations

Differential inhibition of hepatic ferrochelatase by regioisomers of N-butyl-, N-pentyl-, N-hexyl-, and N-isobutylprotoporphyrin IX.

1988 • 15 citations

Observations and comments on the mechanism of epoxidation of alkenes by manganese(III) porphyrins with hypochlorite.

1988 • 15 citations

Kinetics of the β-hydroxy elimination reactions from the protoporphyrin iron(III)–CHRCH2OH complexes in aqueous solutions. A pulse-radiolytic study

1986 • 15 citations

Hemolytic Anemia and Sulfhemoglobinemia Due to Phenacetin Abuse: A Case with Multivisceral Adverse Effects

1981 • 15 citations

Homolytic aromatic substitution of coordinated ligands. Alkylation of phenanthroline with free radicals from organometals

1982 • 14 citations

Proton NMR study of the influence of heme vinyl groups on the formation of the isomeric forms of sulfmyoglobin

1986 • 14 citations

The meso-hydroxylation and meso-benzoxylation of pyridine octaethylhaemochrome

1968 • 14 citations

Electron transfer between hemoglobin and arenediazonium salts. Mechanism of heme aryl-iron complex formation

1987 • 13 citations

Reactions of iron(II) protoporphyrin with strongly reducing free radicals in aqueous solutions. A pulse-radiolytic study

1985 • 13 citations

2,2-Dialkyl-1,2-dihydroquinolines: cytochrome P 450 catalyzed N-alkylporphyrin formation, ferrochelatase inhibition, and induction of 5-aminolevulinic acid synthase activity

1988 • 12 citations

Determination of the chirality of the saturated pyrrole in sulfmyoglobin using the nuclear Overhauser effect

1989 • 12 citations

Mechanism of a novel synthesis of haemin c from protohaemin and L-cysteine. A Markownikoff-type radical addition reaction

1981 • 11 citations

The oxidative breakdown of haemoglobin by 2,3-dimercaptopropanol

1961 • 8 citations

Ethanenitronate is a peroxide-dependent suicide substrate for catalase.

1987 • 7 citations

Reaction of the model thiol 2-mercaptoethanol and glutathione with methylvinylmaleimide, a Michael acceptor with extended conjugation

1987 • 6 citations

THE BLOOD PIGMENT AND CYANIDES; A GREEN HAEMOGLOBIN

1943 • 5 citations

Isolation of N-phenylprotoporphyrin IX from the red cells and spleen of the phenylhydrazine-treated rat

1987 • 5 citations

Reaction of iron(II) protoporphyrin IX with the cyano-radical. The structure of pseudohaem

1969 • 4 citations

The mechanism of hydroperoxide-dependent reactions with participation of cytochrome P-450.

1979 • 4 citations

Preparation of sulfheme derivatives from reconstituted myoglobins lacking the heme vinyl substituents

1987 • 3 citations

The formation of alkylthiohaemoglobins and the structure of their heamatin groups

1968 • 3 citations

ChemInform Abstract: Spectroscopic Studies of Phenyl Iron(IV) Porphyrin Complexes and Their Conversion into Iron(II) N‐Phenylporphyrins.

1986 • 2 citations

ON CRUORALBIN AND ITS PROSTHETIC GROUP

1945 • 2 citations

DEGRADATION OF HEMIN IN THE SYSTEM OF DIGYANHEMATIN-ASCORBIC ACID-H2O2

1957 • 2 citations

The mechanism of hydroperoxide-dependent reactions with participation of cytochrome P-450

1979 • 2 citations

ON SOME PROPERTIES OF CRUORATIN AND ITS RELATIONSHIP TO PSEUDO‐HAEMATIN

1946 • 1 citations

MESOHAEMOGLOBIN DERIVATIVES

1949 • 1 citations

Deleted Work

1955 • 0 citations