Networks and crosstalk: integrin signalling spreads

Integrin Signaling

1999 • 3,705 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages

1997 • 1,218 citations

Regulation of development and differentiation by the extracellular matrix

1993 • 1,216 citations

Signaling through focal adhesion kinase

1999 • 1,169 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

Src family kinases are required for integrin but not PDGFR signal transduction

1999 • 733 citations

Embryonic mesodermal defects in α5 integrin-deficient mice

1993 • 694 citations

Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All αv Integrins

1998 • 649 citations

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

2002 • 604 citations

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

1998 • 574 citations

Mechanotransduction in Response to Shear Stress

1999 • 560 citations

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

2001 • 547 citations

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

2001 • 544 citations

Integrins and cell proliferation

2001 • 509 citations

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

2001 • 485 citations

Interaction of endostatin with integrins implicated in angiogenesis

2001 • 442 citations

Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis

2002 • 434 citations

Integrin αvβ3 Requirement for Sustained Mitogen-activated Protein Kinase Activity during Angiogenesis

1998 • 397 citations

Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression

2001 • 334 citations

Adhesion events in angiogenesis

2001 • 286 citations

Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas in Transgenic Mice

2001 • 277 citations

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

1994 • 247 citations

Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1

2001 • 239 citations

Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors.

1996 • 211 citations

Extracellular Matrix-derived Peptide Binds to αvβ3 Integrin and Inhibits Angiogenesis

2001 • 205 citations

Specific Interaction of Angiostatin with Integrin αvβ3 in Endothelial Cells

2001 • 196 citations

Trans-dominant inhibition of integrin function.

1996 • 174 citations

α4β1 Integrin/VCAM-1 Interaction Activates αLβ2 Integrin-Mediated Adhesion to ICAM-1 in Human T Cells

2000 • 129 citations

Integrins in the Immune System

1999 • 122 citations

Interaction of Very Late Antigen-4 with VCAM-1 Supports Transendothelial Chemotaxis of Monocytes by Facilitating Lateral Migration

1998 • 97 citations

Fibroblast Quiescence in Floating or Released Collagen Matrices

2001 • 92 citations

Soluble VCAM-1 binding to α4 integrins is cell-type specific and activation dependent and is disrupted during apoptosis in T cells

2000 • 87 citations

Integrins Enhance Platelet-derived Growth Factor (PDGF)-dependent Responses by Altering the Signal Relay Enzymes That Are Recruited to the PDGF β Receptor

1999 • 80 citations

VLA-4 (α4β1) engagement defines a novel activation pathway for β2 integrin–dependent leukocyte adhesion involving the urokinase receptor

2000 • 69 citations

β1D Integrin Inhibits Cell Cycle Progression in Normal Myoblasts and Fibroblasts

1998 • 64 citations

Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases

2001 • 17 citations