Nitric oxide inhibits growth of glomerular mesangial cells: Role of the transcription factor EGR-1

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide synthases: Roles, tolls, and controls

1994 • 2,945 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

NO at work

1994 • 1,493 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors

1991 • 1,223 citations

Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.

1994 • 1,102 citations

DNA damage and mutation in human cells exposed to nitric oxide in vitro.

1992 • 980 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

DNA binding site of the growth factor-inducible protein Zif268.

1989 • 563 citations

The high-output nitric oxide pathway: role and regulation

1994 • 512 citations

Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

1996 • 455 citations

The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.

1994 • 447 citations

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway.

1993 • 393 citations

Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione

1985 • 389 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras

1995 • 367 citations

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

1990 • 343 citations

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.

1987 • 292 citations

Nitric Oxide in the Kidney: Synthesis, Localization, and Function

1994 • 290 citations

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

1991 • 277 citations

Nitric Oxide Destroys Zinc-Sulfur Clusters Inducing Zinc Release from Metallothionein and Inhibition of the Zinc Finger-Type Yeast Transcription Activator LAC9

1994 • 276 citations

Glomerular actions of nitric oxide

1995 • 267 citations

The serum-inducible mouse gene Krox-24 encodes a sequence-specific transcriptional activator.

1990 • 256 citations

Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat.

1992 • 248 citations

Inhibition of rat mesangial cell mitogenesis by nitric oxide-generating vasodilators

1989 • 166 citations

NF-κB and AP-1 Activation by Nitric Oxide Attenuated Apoptotic Cell Death in RAW 264.7 Macrophages

1999 • 157 citations

Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis.

1995 • 154 citations

Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues

1990 • 143 citations

Glomeruli synthesize nitrite in experimental nephrotoxic nephritis

1990 • 137 citations

Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene

1991 • 118 citations

Hypertensive nephrosclerosis in the Dahl/Rapp rat. Initial sites of injury and effect of dietary L-arginine supplementation.

1993 • 117 citations

Dietary Supplementation With l-Arginine Ameliorates the Progression of Renal Disease in Rats With Subtotal Nephrectomy

1992 • 116 citations

Macrophages in acute glomerular inflammation

1994 • 114 citations

Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase

1994 • 112 citations

The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cells.

1997 • 105 citations

Nitric oxide donors induce apoptosis in glomerular mesangial cells, epithelial cells and endothelial cells

1996 • 96 citations

The immediate-early gene Egr-1 regulates the activity of the thymidine kinase promoter at the G0-to-G1 transition of the cell cycle.

1994 • 95 citations

Nitric Oxide: An Inflammatory Mediator of Glomerular Mesangial Cells

1993 • 87 citations

Glomeruli synthesize nitrite in active Heymann nephritis; the source is infiltrating macrophages

1991 • 76 citations

Glomerular NO synthase activity in mesangial cell immune injury.

1993 • 73 citations

Endothelium-derived relaxing factor, nitric oxide

1993 • 66 citations

Transcription Factor Egr-1 Regulates Glomerular Mesangial Cell Proliferation

1996 • 61 citations

Mechanism of atrial natriuretic factor-induced inhibition of rat mesangial cell mitogenesis.

1990 • 58 citations

Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components

1998 • 52 citations

Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: correlation with mitogenicity

1992 • 50 citations

PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements

1993 • 48 citations

Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis.

1994 • 42 citations

Expression of the transcriptional regulator Egr-1 in experimental glomerulonephritis: Requirement for mesangial cell proliferation

1997 • 28 citations

Growth of LLC-PK1 renal cells is mediated by EGR-1 up-regulation of G protein alpha i-2 protooncogene transcription.

1994 • 23 citations

Mitogenic Signals Control Translation of the Early Growth Response Gene-1 in Myogenic Cells

1994 • 13 citations

Nitric oxide in the juxtaglomerular apparatus.

1996 • 12 citations

Serum response elements mediate protein kinase C dependent transcriptional induction of early growth response gene‐1 by arginine vasopressin in rat mesangial cells

1994 • 10 citations