Transcriptional stimulation of the delta 1-crystallin gene by insulin-like growth factor I and insulin requires DNA cis elements in chicken.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

LENS CRYSTALLINS: THE EVOLUTION AND EXPRESSION OF PROTEINS FOR A HIGHLY SPECIALIZED TISSUE

1988 • 770 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

A simple method of preparing large amounts of ΦX174 RF I supercoiled DNA

1973 • 265 citations

Activity of two different silencer elements of the chicken lysozyme gene can be compensated by enhancer elements.

1987 • 226 citations

Antibodies to Purified Insulin Receptor Have Insulin-Like Activity

1978 • 222 citations

Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor.

1984 • 199 citations

Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells.

1987 • 194 citations

Identification of c-fos sequences involved in induction by insulin and phorbol esters.

1988 • 184 citations

Insulin Receptors, Receptor Antibodies, and the Mechanism of Insulin Action

1981 • 170 citations

Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors.

1987 • 165 citations

Identification of a cAMP regulatory region in the gene for rat cytosolic phosphoenolpyruvate carboxykinase (GTP). Use of chimeric genes transfected into hepatoma cells.

1984 • 155 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.

1987 • 155 citations

Insulinlike growth factor I regulation of growth hormone gene transcription in primary rat pituitary cells.

1987 • 138 citations

Characterization of Induction of Protooncogene c-myc and Cellular Growth in Human Vascular Smooth Muscle Cells by Insulin and IGF-I

1989 • 135 citations

Multiple Protein-Binding Sites in the 5′-Flanking Region Regulate c-fos Expression

1986 • 133 citations

Lens-specific expression of the chloramphenicol acetyltransferase gene promoted by 5' flanking sequences of the murine alpha A-crystallin gene in explanted chicken lens epithelia.

1985 • 132 citations

Chicken embryo lens cultures mimic differentiation in the lens

1984 • 125 citations

Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.

1988 • 122 citations

Lens-specific enhancer in the third intron regulates expression of the chicken delta 1-crystallin gene.

1987 • 114 citations

Monoclonal antibodies to the human insulin receptor that activate glucose transport but not insulin receptor kinase activity.

1987 • 89 citations

Evidence for positive and negative regulation in the promoter of the chicken δ1-crystallin gene

1988 • 81 citations

Insulin-receptor antibodies mimic a late insulin effect

1979 • 77 citations

Molecular cloning of gene sequences that are regulated by insulin-like growth factor I.

1987 • 71 citations

Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor

1987 • 68 citations

Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts.

1989 • 63 citations

Insulin-like Growth Factor I and Insulin Regulate δ-Crystallin Gene Expression in Developing Lens

1989 • 51 citations

Insulin and Dexamethasone Regulation of a Rat Hepatoma Messenger Ribonucleic Acid: Insulin Has a Transcriptional and a Posttranscriptional Effect*

1989 • 50 citations

Insulin-Like Growth Factor I Induces c-fos Messenger Ribonucleic Acid in L6 Rat Skeletal Muscle Cells*

1987 • 49 citations

Structural and functional evidence for differential promoter activity of the two linked delta-crystallin genes in the chicken.

1985 • 46 citations

Insulin and IGF receptors are developmentally regulated in the chick embryo eye lens

1987 • 46 citations

Insulin response of a hybrid amylase/CAT gene in transgenic mice.

1988 • 40 citations

Insulin regulates expression of the human growth hormone gene in transfected cells.

1988 • 34 citations

Binding of nuclear proteins to promoter elements of the mouse alpha A-crystallin gene.

1988 • 29 citations

In vivo competition of delta-crystallin gene expression by DNA fragments containing a GC box.

1986 • 18 citations

The chicken delta 1-crystallin gene promoter: binding of transcription factor(s) to the upstream G+C-rich region is necessary for promoter function in vitro.

1986 • 18 citations

Stimulation of Protein Synthesis in Stage IV Xenopus Oocytes by Microinjected Insulin

1989 • 16 citations

Insulin-related receptors in the early chick embryo: from tissue patterns to possible function.

1987 • 10 citations

In Vivo Competition of δ-Crystallin Gene Expression by DNA Fragments Containing a GC Box

1986 • 5 citations