Angiogenesis

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Angiogenic Factors

1987 • 3,702 citations

Hemangiomas and Vascular Malformations in Infants and Children

1982 • 3,187 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Transforming Growth Factor-β: Biological Function and Chemical Structure

1986 • 1,198 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Angiogenesis in vitro

1980 • 1,041 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Heparin protects basic and acidic FGF from inactivation

1986 • 856 citations

Transforming Growth Factor-α: a More Potent Angiogenic Mediator than Epidermal Growth Factor

1986 • 856 citations

Basic fibroblast growth factor induces angiogenesis in vitro.

1986 • 828 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Long-term culture of capillary endothelial cells.

1979 • 780 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

1974 • 762 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Oxygen Tension Regulates the Expression of Angiogenesis Factor by Macrophages

1983 • 689 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor.

1984 • 624 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices.

1983 • 616 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.

1987 • 607 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

1984 • 562 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

A New Class of Steroids Inhibits Angiogenesis in the Presence of Heparin or a Heparin Fragment

1985 • 492 citations

Mast cell heparin stimulates migration of capillary endothelial cells in vitro.

1980 • 445 citations

STUDIES ON INFLAMMATION. III. GROWING CAPILLARIES: THEIR STRUCTURE AND PERMEABILITY.

1963 • 430 citations

Biology of Endothelial Cells

1984 • 426 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Relation of vascular proliferation to tumor growth.

1976 • 413 citations

Role of prostaglandin E1 and copper in angiogenesis.

1982 • 393 citations

Heparin Binds Endothelial Cell Growth Factor, the Principal Endothelial Cell Mitogen in Bovine Brain

1984 • 391 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

Hyaluronate in Vasculogenesis

1983 • 368 citations

Amino acid sequence of human tumor derived angiogenin

1985 • 357 citations

Characteristic ribonucleolytic activity of human angiogenin

1986 • 354 citations

Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.

1986 • 354 citations

Basement Membrane Collagen: Degradation by Migrating Endothelial Cells

1983 • 345 citations

PGE2 and Angiogenesis

1983 • 341 citations

Basic and acidic fibroblast growth factors interact with the same cell surface receptors.

1986 • 340 citations

Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells.

1984 • 339 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Serum contains a platelet-derived transforming growth factor.

1982 • 330 citations

Studies on inflammation and wound healing: angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages.

1984 • 316 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Isolations of a Cartilage Factor That Inhibits Tumor Neovascularization

1976 • 308 citations

Studies on inflammation

1963 • 306 citations

Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition.

1985 • 301 citations

Purification of two distinct growth factors from bovine neural tissue by heparin affinity chromatography

1984 • 298 citations

Differentiation of vascular endothelium in the chick chorioallantois: A structural and autoradiographic study

1974 • 294 citations

Tumor Angiogenesis: Transfilter Diffusion Studies in the Hamster by the Transparent Chamber Technique<xref ref-type="fn" rid="FN2">2</xref>

1968 • 288 citations

Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts

1986 • 285 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Cloning and sequencing of the intronless gene for angiogenin, a human angiogenesis factor

1985 • 273 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase.

1984 • 269 citations

Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors

1985 • 268 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Lipid Angiogenic Factor From Omentum

1984 • 233 citations

Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels.

1975 • 233 citations

Migration of capillary endothelial cells is stimulated by tumour-derived factors

1980 • 227 citations

Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities.

1984 • 224 citations

Isolation of a nonmitogenic angiogenesis factor from wound fluid.

1982 • 219 citations

Heparin affinity of anionic and cationic capillary endothelial cell growth factors: analysis of hypothalamus-derived growth factors and fibroblast growth factors.

1985 • 214 citations

A Possible Mechanism for Inhibition of Angiogenesis by Angiostatic Steroids: Induction of Capillary Basement Membrane Dissolution*

1986 • 214 citations

Role of the pericyte in wound healing

1970 • 211 citations

Neovasculogenic Ability of Prostaglandins, Growth Factors, and Synthetic Chemoattractants

1978 • 205 citations

Angiogenesis is stimulated by a tumor‐derived endothelial cell growth factor

1985 • 203 citations

Toward an Understanding of Angiogenesis: Search and Discovery

1985 • 184 citations

A family of angiogenic peptides

1987 • 178 citations

Production a corpus luteum angiogenic factor responsible for proliferation of capillaries and neovascularization of the corpus luteum.

1978 • 174 citations

Purification and properties of human platelet heparitinase.

1982 • 154 citations

Control of tumor growth in animals by infusion of an angiogenesis inhibitor.

1980 • 154 citations

Wound Healing and Wound Infection: Theory and Surgical Practice

1981 • 150 citations

The sequence of events in the regression of corneal capillaries.

1978 • 141 citations

Bovine retina contains three growth factor activities with different affinity to heparin: eye derived growth factor I, II, III

1985 • 139 citations

Interaction of T lymphocytes and macrophages with cultured vascular endothelial cells: Attachment, invasion, and subsequent degradation of the subendothelial extracellular matrix

1984 • 133 citations

Neurite outgrowth induced by an endothelial cell mitogen isolated from retina.

1986 • 131 citations

Purification of cartilage-derived growth factor by heparin affinity chromatography.

1985 • 129 citations

Studies on retinal neovascularization. Friedenwald Lecture.

1980 • 127 citations

Observations on living preformed blood vessels as seen in a transparent chamber inserted into the rabbit's ear

1932 • 125 citations

Sarcoma growth factor (SGF): Specific binding to epidermal growth factor (EGF) membrane receptors

1980 • 123 citations

Differentiation-dependent stimulation of neovascularization and endothelial cell chemotaxis by 3T3 adipocytes.

1982 • 123 citations

International Review of Experimental Pathology

1977 • 117 citations

The characterization of the receptor for endothelial cell growth factor by covalent ligand attachment.

1986 • 111 citations

Evidence and characterization of the receptor to eye-derived growth factor I, the retinal form of basic fibroblast growth factor, on bovine epithelial lens cells.

1986 • 105 citations

Tissue Distribution and Developmental Expression of the Messenger RNA Encoding Angiogenin

1987 • 104 citations

Potent stimulation of vascular endothelial cell growth by differentiated 3T3 adipocytes.

1980 • 83 citations

Vitreous: an inhibitor of retinal extract-induced neovascularization.

1983 • 78 citations

Dissociation of the chemotactic and mitogenic activities of platelet-derived growth factor by human neutrophil elastase.

1985 • 77 citations

Sequential degradation of heparan sulfate in the subendothelial extracellular matrix by highly metastatic lymphoma cells

1985 • 75 citations

Demonstration of angiogenesis-activity in the corpus luteum of cattle

1977 • 67 citations

The isolation and purification of two anionic endothelial cell growth factors from human brain

1984 • 66 citations

Wound healing and wound infection : theory and surgical practice

1980 • 66 citations

Purification and partial amino acid sequence of a bovine cartilage-derived collagenase inhibitor.

1986 • 61 citations

Toward a New Understanding of Vascular Proliferative Disease in Children

1984 • 58 citations

Extracellular matrix and capillary ingrowth in interspecies chimeric kidneys

1984 • 48 citations

Proteoglycans in the microvascular. II. Histochemical localization in proliferating capillaries of the rabbit cornea.

1981 • 48 citations

Localized vascular regression during limb morphogenesis in the chicken embryo. I. Spatial and temporal changes in the vascular pattern

1986 • 47 citations

Localized vascular regression during limb morphogenesis in the chicken embryo: II. Morphological changes in the vasculature

1986 • 44 citations

Culture of capillary endothelial cells

1984 • 36 citations

ON THE ORIGIN OF THE CELLS OF THE BLOOD

1922 • 33 citations

Experimentelle Untersuchungen über die Entwickelung der Blutcapillaren

1871 • 29 citations

VASCULAR DISEASES: CURRENT RESEARCH AND CLINICAL APPLICATIONS

1988 • 26 citations

Presence of heparin binding growth factor in mouse bladder tumors and urine from mice with bladder cancer.

1986 • 23 citations

Vitreous: Inhibitor retinal extract induced neovascularization

1984 • 19 citations

Neomorphogenesis of blood vessels in rabbit skin induced by a highly purified monocyte-derived polypeptide (monocyto-angiotropin) and associated tissue reactions.

1984 • 11 citations