METABOLISM OF ARACHIDONIC ACID AND ITS ENDOPEROXIDE (PGH₂) TO MYOTROPIC PRODUCTS IN GUINEA‐PIG AND RABBIT ISOLATED LUNGS

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Prostaglandins and Thromboxanes

1978 • 1,310 citations

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

1976 • 1,012 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

Isolation and properties of intermediates in prostaglandin biosynthesis

1973 • 796 citations

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1977 • 683 citations

The release and fate of vaso‐active hormones in the circulation

1969 • 639 citations

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

1976 • 533 citations

THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD

1964 • 478 citations

UNSTABLE METABOLITES OF ARACHIDONIC ACID AND THEIR ROLE IN HAEMOSTASIS AND THROMBOSIS

1978 • 447 citations

Prostacyclin is a circulating hormone

1978 • 380 citations

Generation of prostacyclin by lungs in vivo and its release into the arterial circulation

1978 • 374 citations

: A selective inhibitor of thromboxane synthetase

1977 • 303 citations

Metabolism of prostaglandin endoperoxide in animal tissues

1977 • 287 citations

Cardiac and Renal Prostaglandin I2

1978 • 174 citations

RECIRCULATION OF PROSTACYCLIN (PGI₂) IN THE DOG

1978 • 167 citations

Lipid metabolism in cultured cells

1966 • 158 citations

Diversion of prostaglandin endoperoxide metabolism by selective inhibition of thromboxane A2 biosynthesis in lung, spleen or platelets

1977 • 106 citations

The effects of prostacyclin (PGI2) on tissues which detect prostaglandins (PG'S)

1977 • 103 citations

Transformation of arachidonic acid and prostaglandin endoperoxides by the guinea pig heart. Formation of RCS and prostacyclin

1978 • 96 citations

Synthesis of prostaglandin 6-keto F1α by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates

1978 • 70 citations

THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD

1997 • 60 citations

Lipid metabolism in cultured cells. Synthesis of vasoactive thromboxane A2 from [14C]arachidonic acid culture lung fibroblasts.

1978 • 58 citations

The effects of prostagladin endoperoxides and thromboxane A2 on strips of rabbit coeliac artery and certain other smooth muscle preparations [proceedings].

1976 • 48 citations

Lipid Metabolism in Cultured Cells

1973 • 48 citations

Thromboxane A2 biosynthesis in human lung fibroblasts WI-38

1978 • 47 citations

Enzymatic preparation of prostaglandin endoperoxides

1977 • 29 citations

Detection and bioassay of pharmacologically active substances released by arachidonic acid from guinea-pig perfused lungs

1978 • 12 citations

Differential synthesis and metabolism of prostaglandins and thromboxanes released from normal and sensitized guinea-pig lungs [proceedings].

1977 • 8 citations

PGI2 release from guinea-pig lungs: detection and bioassay [proceedings].

1978 • 6 citations

1977 winter prostaglandin conference

1977 • 5 citations

Metabolism of arachidonic acid and its endoperoxide prostaglandin H2 in isolated lungs from guinea-pigs and rabbits [proceedings].

1979 • 2 citations

What is the fate of exogenous prostaglandin endoperoxide, PGH2, in isolated lung? [proceedings].

1979 • 1 citations