Metabolism of prostaglandin endoperoxide in animal tissues

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs

1969 • 886 citations

Isolation and properties of intermediates in prostaglandin biosynthesis

1973 • 796 citations

The chemical structure of prostaglandin X (prostacyclin)

1976 • 729 citations

THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD

1964 • 478 citations

Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular glands

1972 • 362 citations

Prostaglandin endoperoxide E isomerase from bovine vesicular gland microsomes, a glutathione-requiring enzyme.

1977 • 212 citations

Novel prostaglandin derivative formed from arachidonic acid by rat stomach homogenates

1971 • 163 citations

Conversions of prostaglandin endoperoxides by glutathione-S-transferases and serum albumins

1976 • 138 citations

Prostaglandins and the regulation of uterine blood flow in pregnancy

1974 • 137 citations

Inhibition of human platelet thromboxane synthetase by 9,11-azoprosta-5,13-dienoic acid.

1977 • 111 citations

Characterization of a novel metabolic pathway of arachidonate in coronary arteries which generates a potent endogenous coronary vasodilator.

1977 • 101 citations

Prostaglandins H1 and H2. Convenient biochemical synthesis and isolation. Further biological and spectroscopic characterization

1977 • 80 citations

Prostaglandin E1 and F2α specific binding in bovine corpora lutea: Comparison with luteolytic effects

1975 • 75 citations

Ionophore A 23187-Induced Production of Slow Reacting Substance of Anaphylaxis (SRS-A) by Rat Peritoneal Cells in Vitro: Evidence for Production by Mononuclear Cells

1978 • 74 citations

Biosynthesis of thromboxanes in human platelets. I. Characterization and assay of thromboxane systhetase

1977 • 66 citations

Prostaglandin E1 and F2α specific binding in bovine corpora lutea: Comparison with luteolytic effects

1975 • 55 citations

Involvement of endoperoxides and thromboxanes in anaphylactic reactions.

1976 • 53 citations

Metabolism of prostaglandin F2α, in rhesus monkeys

1974 • 52 citations

N-0164 inhibits generation of thromboxane-A2-like activity from prostaglandin endoperoxides by human platelet microsomes

1976 • 45 citations

Identification of 6-ketoprostaglandin f1α formed from arachidonic acid in bovine seminal vesicles

1977 • 40 citations

Introduction: new trends in prostaglandin research.

1976 • 36 citations

Prostaglandins and the initiation of labor

1976 • 22 citations