Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

2000 • 2,694 citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1997 • 936 citations

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1999 • 824 citations

Mice deficient for the CD40 ligand

1994 • 753 citations

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40–CD40 ligand signaling in atherosclerosis

1997 • 737 citations

Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand

2000 • 646 citations

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance

1999 • 621 citations

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

1995 • 496 citations

Predominant role for C5b-9 in renal ischemia/reperfusion injury

2000 • 443 citations

The Role of CD40 Ligand in Costimulation and T‐Cell Activation

1996 • 441 citations

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.

1994 • 431 citations

Resistance of Fc receptor- deficient mice to fatal glomerulonephritis.

1998 • 271 citations

Cutting Edge: Administration of Anti-CD40 Ligand and Donor Bone Marrow Leads to Hemopoietic Chimerism and Donor-Specific Tolerance Without Cytoreductive Conditioning

2000 • 257 citations

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions.

1993 • 250 citations

Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8+ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner

2000 • 216 citations

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance

2000 • 202 citations

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

1987 • 190 citations

An H–YDb epitope is encoded by a novel mouse Y chromosome gene

1996 • 181 citations

DIFFERENTIAL EFFECTS OF CYCLOSPORINE A, METHYLPREDNISOLONE, MYCOPHENOLATE, AND RAPAMYCIN ON CD154 INDUCTION AND REQUIREMENT FOR NF??B

2000 • 161 citations

THE MALE-SPECIFIC HISTOCOMPATIBILITY ANTIGEN, H-Y:A History of Transplantation, Immune Response Genes, Sex Determination and Expression Cloning

1997 • 155 citations

CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection

1996 • 154 citations

Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1.

1993 • 95 citations

THE ALLOGENEIC T AND B CELL RESPONSE IS STRONGLY DEPENDENT ON COMPLEMENT COMPONENTS C3 AND C41

2001 • 94 citations

Transplantation tolerance—where do we stand?

1999 • 89 citations

The role of T cell apoptosis in transplantation tolerance

2000 • 83 citations

T Cell Costimulatory Blockade

1999 • 75 citations

Examination of HY Response: T Cell Expansion, Immunodominance, and Cross-Priming Revealed by HY Tetramer Analysis

2001 • 73 citations

CD40 ligand‐independent B cell activation revealed by CD40 ligand‐deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation

1995 • 66 citations

IL-2 Receptor-Targeted Cytolytic IL-2/Fc Fusion Protein Treatment Blocks Diabetogenic Autoimmunity in Nonobese Diabetic Mice

1999 • 61 citations

Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases

2000 • 47 citations

The role of peripheral T–cell deletion in transplantation tolerance

2001 • 44 citations

Interleukin 2 receptor targeted fusion toxin (DAB₄₈₆‐IL‐2) treatment blocks diabetogenic autoimmunity in non‐obese diabetic mice

1992 • 41 citations

Interleukin-2 Receptor-Directed Therapies: Antibody-or Cytokine-Based Targeting Molecules

1993 • 39 citations

T cells are just dying to accept grafts

1999 • 33 citations

Reply to Failure of combined costimulatory blockade in animal transplant model

2000 • 10 citations

Current trends in transplant immunology

1999 • 8 citations