Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell

Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

1997 • 3,163 citations

Protein modules and signalling networks

1995 • 2,447 citations

Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells

1998 • 1,509 citations

Protein molecules as computational elements in living cells

1995 • 720 citations

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand‐receptor interactions

1997 • 719 citations

Fluorescence ratio imaging of cyclic AMP in single cells

1991 • 686 citations

A continuously variable frequency cross-correlation phase fluorometer with picosecond resolution

1983 • 475 citations

Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation.

1995 • 432 citations

Fluorescence lifetime imaging microscopy (FLIM): Spatial resolution of microstructures on the nanosecond time scale

1993 • 364 citations

Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer

1998 • 301 citations

Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin.

1996 • 286 citations

Fluorescence imaging spectroscopy and microscopy

1997 • 284 citations

Lifetime-selective fluorescence imaging using an rf phase-sensitive camera

1991 • 251 citations

The PTB domain: a new protein module implicated in signal transduction

1995 • 249 citations

Construction and performance of a variable-frequency phase-modulation fluorometer

1985 • 231 citations

Optical microscopy for biology

1991 • 197 citations

Quantitative pH Imaging in Cells Using Confocal Fluorescence Lifetime Imaging Microscopy

1995 • 185 citations

A Two-Dimensional Fluorescence Lifetime Imaging System Using a Gated Image Intensifier

1991 • 147 citations

Time‐gated fluorescence lifetime imaging and microvolume spectroscopy using two‐photon excitation

1998 • 116 citations

Rapid acquisition, analysis, and display of fluorescence lifetime-resolved images for real-time applications

1997 • 109 citations

Fluorescence lifetime imaging by asynchronous pump-probe microscopy

1995 • 107 citations

Time-resolved fluorescence lifetime imaging microscopy using a picosecond pulsed tunable dye laser system

1996 • 94 citations

[30] Fluorescence lifetime imaging microscopy: Homodyne technique using high-speed gated image intensifier

1994 • 61 citations

Confocal fluorescence microscopy using spectral and lifetime information to simultaneously record four fluorophores with high channel separation

1997 • 60 citations

High-frequency modulated light source for phase fluorometry and fluorescence lifetime imaging

1995 • 8 citations