Hydrophobic cluster analysis predicts an amino-terminal domain of varicella-zoster virus open reading frame 10 required for transcriptional activation.

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

The Complete DNA Sequence of Varicella-Zoster Virus

1986 • 1,425 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

The DNA sequence of equine herpesvirus-1

1992 • 644 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Critical Structural Elements of the VP16 Transcriptional Activation Domain

1991 • 461 citations

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

1983 • 423 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Hydrophobic cluster analysis: procedures to derive structural and functional information from 2-D-representation of protein sequences

1990 • 300 citations

Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator.

1993 • 261 citations

The varicella-zoster virus immediate-early protein IE62 is a major component of virus particles

1992 • 164 citations

Detection of secondary structure elements in proteins by hydrophobic cluster analysis

1992 • 148 citations

Genetic evidence that an activation domain of GAL4 does not require acidity and may form a β sheet

1993 • 138 citations

The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.

1989 • 127 citations

DNA sequence of the herpes simplex virus type 1 gene whose product is responsible for transcriptional activation of immediate early promoters

1985 • 122 citations

An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator

1991 • 119 citations

The Varicella-Zoster virus immediate early protein, IE62, can positively regulate its cognate promoter

1992 • 100 citations

Varicella-Zoster Virus (VZV) Virion-Associated Transactivator Open Reading Frame 62 Protein Enhances the Infectivity of VZV DNA

1994 • 84 citations

Protein and DNA elements involved in transactivation of the promoter of the bovine herpesvirus (BHV) 1 IE-1 transcription unit by the BHV alpha gene trans-inducing factor

1994 • 82 citations

Varicella-zoster virus open reading frame 10 protein, the herpes simplex virus VP16 homolog, transactivates herpesvirus immediate-early gene promoters

1993 • 75 citations

Varicella-zoster virus (VZV) open reading frame 61 protein transactivates VZV gene promoters and enhances the infectivity of VZV DNA

1993 • 72 citations

Transcriptional Activation by the Acidic Domain of Vmw65 Requires the Integrity of the Domain and Involves Additional Determinants Distinct from Those Necessary for TFIIB Binding

1993 • 65 citations

Equid Herpesviruses 1 and 4 Encode Functional Homologs of the Herpes Simplex Virus Type 1 Virion Transactivator Protein, VP16

1994 • 42 citations

The transcriptional activation domain of varicella-zoster virus open reading frame 62 protein is not conserved with its herpes simplex virus homolog

1993 • 35 citations

Nucleotide and predicted amino acid sequences of Marek's disease virus homologues of herpes simplex virus major tegument proteins

1993 • 35 citations

Varicella-zoster virus DNA polymerase and major DNA-binding protein genes have overlapping divergent promoters

1993 • 31 citations

Nucleotide and deduced amino acid sequences of the gene encoding virion protein 16 of herpes simplex virus type 2

1991 • 23 citations

Sequences of the bovine herpesvims 1 homologue of herpes simplex virus type-1 α-trans-inducing factor (UL48)

1992 • 23 citations

The extreme carboxyl terminus of the equine herpesvirus 1 homolog of herpes simplex virus VP16 is essential for immediate-early gene activation

1994 • 22 citations

Predicted common structural features of DNA-binding domains from Ets, Myb and HMG transcription factors

1993 • 9 citations

Putative dimeric organization of nuclear receptor hormone-binding domains, deduced from hydrophobic cluster analysis.

1994 • 4 citations