Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

1999 • 1,558 citations

Positional Cloning of the Mouse Circadian Gene

1997 • 1,335 citations

Interacting Molecular Loops in the Mammalian Circadian Clock

2000 • 1,332 citations

Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau

2000 • 850 citations

double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation

1998 • 820 citations

Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim

1998 • 799 citations

A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless

1998 • 718 citations

CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless

1998 • 631 citations

Negative Feedback Defining a Circadian Clock: Autoregulation of the Clock Gene frequency

1994 • 596 citations

Molecular Genetics of Circadian Rhythms in Mammals

2000 • 541 citations

Neurospora wc-1 and wc-2 : Transcription, Photoresponses, and the Origins of Circadian Rhythmicity

1997 • 494 citations

White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein.

1996 • 449 citations

Interlocked Feedback Loops Within the Drosophila Circadian Oscillator

1999 • 361 citations

White collar 2,a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa

1997 • 356 citations

Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript

1995 • 356 citations

Interconnected Feedback Loops in the Neurospora Circadian System

2000 • 352 citations

Alternative Initiation of Translation and Time-Specific Phosphorylation Yield Multiple Forms of the Essential Clock Protein FREQUENCY

1997 • 346 citations

Thermally Regulated Translational Control of FRQ Mediates Aspects of Temperature Responses in the Neurospora Circadian Clock

1997 • 256 citations

PER and TIM Inhibit the DNA Binding Activity of a Drosophila CLOCK-CYC/dBMAL1 Heterodimer without Disrupting Formation of the Heterodimer: a Basis for Circadian Transcription

1999 • 239 citations

Role of a white collar-1-white collar-2 complex in blue-light signal transduction

1999 • 236 citations

How Temperature Changes Reset a Circadian Oscillator

1998 • 231 citations

The Drosophila CLOCK Protein Undergoes Daily Rhythms in Abundance, Phosphorylation, and Interactions with the PER–TIM Complex

1998 • 231 citations

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.

1994 • 221 citations

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

2000 • 203 citations

WC-2 mediates WC-1-FRQ interaction within the PAS protein-linked circadian feedback loop of Neurospora

2001 • 185 citations

Roles in dimerization and blue light photoresponse of the PAS and LOV domains of Neurospora crassa white collar proteins

1998 • 180 citations

Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora

2001 • 170 citations

Distinct cis-Acting Elements Mediate Clock, Light, and Developmental Regulation of the Neurospora crassa eas (ccg-2) Gene

1996 • 162 citations

Dissection of a circadian oscillation into discrete domains

1997 • 119 citations

Circadian Clock-Specific Roles for the Light Response Protein WHITE COLLAR-2

2001 • 41 citations

Molecular control of circadian behavioral rhythms.

1999 • 16 citations

As Time PASses: The First Mammalian Clock Gene

1997 • 6 citations