Interlocked Feedback Loops Within the Drosophila Circadian Oscillator

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

1990 • 1,103 citations

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

1999 • 894 citations

CRY, a Drosophila Clock and Light-Regulated Cryptochrome, Is a Major Contributor to Circadian Rhythm Resetting and Photosensitivity

1998 • 861 citations

Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim

1998 • 799 citations

A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless

1998 • 718 citations

The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε

1998 • 678 citations

Independent Photoreceptive Circadian Clocks Throughout Drosophila

1997 • 628 citations

Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless

1994 • 627 citations

Temporal phosphorylation of the Drosophila period protein.

1994 • 410 citations

Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila

1990 • 404 citations

Rhythmic Expression of timeless : A Basis for Promoting Circadian Cycles in period Gene Autoregulation

1995 • 368 citations

Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms

1992 • 326 citations

Robust circadian rhythmicity of Drosophila melanogaster requires the presence of lateral neurons: a brain-behavioral study of disconnected mutants

1998 • 296 citations

Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock

1995 • 275 citations

A promoterless period gene mediates behavioral rhythmicity and cyclical per expression in a restricted subset of the drosophila nervous system

1994 • 258 citations

Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling

1997 • 257 citations

PER and TIM Inhibit the DNA Binding Activity of a Drosophila CLOCK-CYC/dBMAL1 Heterodimer without Disrupting Formation of the Heterodimer: a Basis for Circadian Transcription

1999 • 239 citations

A Circadian Enhancer Mediates PER-Dependent mRNA Cycling in Drosophila melanogaster

1997 • 237 citations

The Drosophila CLOCK Protein Undergoes Daily Rhythms in Abundance, Phosphorylation, and Interactions with the PER–TIM Complex

1998 • 231 citations

Circadian Regulation of a Drosophila Homolog of the Mammalian Clock Gene: PER and TIM Function as Positive Regulators

1998 • 217 citations