Differential regulation of MAP kinase activity by corticotropin-releasing hormone in normal and neoplastic corticotropes

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

The MAPK signaling cascade

1995 • 3,300 citations

The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation

1995 • 2,525 citations

Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

1997 • 1,247 citations

Physiology and pharmacology of corticotropin-releasing factor.

1991 • 1,138 citations

cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway

1997 • 1,047 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

Inhibition by cAMP of Ras-Dependent Activation of Raf

1993 • 955 citations

MAPKs: new JNK expands the group

1994 • 949 citations

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

1993 • 939 citations

Hypothalamic Control of Adrenocorticotropin Secretion: Advances since the Discovery of 41-Residue Corticotropin-Releasing Factor

1986 • 874 citations

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

1995 • 578 citations

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

1995 • 525 citations

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells.

1994 • 473 citations

A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel

1989 • 466 citations

Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells.

1994 • 326 citations

Ectopic Secretion of Corticotropin-Releasing Factor as a Cause of Cushing’s Syndrome

1984 • 283 citations

Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells.

1983 • 275 citations

Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors

1996 • 275 citations

Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice.

1992 • 254 citations

Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase.

1990 • 245 citations

Protein kinase C and its substrates

1996 • 236 citations

G protein‐coupled receptors and signaling pathways regulating growth responses ¹

1996 • 221 citations

Chronic Administration of Corticotropin-Releasing Factor Increases Pituitary Corticotroph Number*

1987 • 178 citations

Physiopathology of Cushing's Disease

1983 • 170 citations

Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway.

1996 • 156 citations

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen‐activated protein kinase

1994 • 125 citations

Corticotropin‐releasing factor: an antireproductive hormone of the testis

1993 • 125 citations

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1.

1995 • 92 citations

Spontaneous and Corticotropin-Releasing Factor-Induced Cytosolic Calcium Transients in Corticotrophs*

1991 • 91 citations

The biosynthesis and secretion of adrenocorticotropin by the ovine anterior pituitary is predominantly regulated by arginine vasopressin (AVP). Evidence that protein kinase C mediates the action of AVP.

1990 • 90 citations

Detection of protein kinase activity in sodium dodecyl sulfate-polyacrylamide gels

1986 • 87 citations

Corticotropin-releasing factor-induced adrenocorticotropin hormone release and synthesis is blocked by incorporation of the inhibitor of cyclic AMP-dependent protein kinase into anterior pituitary tumor cells by liposomes.

1985 • 84 citations

Leukemia inhibitory factor induces differentiation of pituitary corticotroph function: an immuno-neuroendocrine phenotypic switch.

1996 • 75 citations

Atriopeptin: an endogenous corticotropin-release inhibiting hormone.

1992 • 73 citations

Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice

1992 • 73 citations

Studies of the Regulation of the Hypothalamic-Pituitary-Adrenal Axis in Sheep with Hypothalamic-Pituitary Disconnection. II. Evidence forin VivoUltradian Hypersecretion of Proopiomelanocortin Peptides by the Isolated Anterior and Intermediate Pituitary*

1990 • 62 citations

The mitogenic effects of corticotrophin-releasing factor on the anterior pituitary gland of the rat

1988 • 52 citations

Corticotropin-releasing hormone stimulation of Ca2+ entry in corticotropes is partially dependent on protein kinase A.

1995 • 49 citations

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1

1995 • 48 citations

Anti-Inflammatory Peptide Agonists

1993 • 46 citations

A Complex Mechanism of Facilitation in Pituitary Acth Cells: Recent Single-Cell Studies

1988 • 42 citations

Signal Transduction: Switching off MAP kinases

1994 • 40 citations

Atriopeptin: an endogenous corticotropin-release inhibiting hormone

1992 • 37 citations

Activation of Protein Kinase C and L Calcium Channels Enhances Binding of Biotinylated Corticotropin-Releasing Hormone by Anterior Pituitary Corticotropes

1989 • 35 citations

Epidermal growth factor enhances ACTH secretion and expression of POMC mRNA by corticotropes in mixed and enriched cultures

1991 • 31 citations

Steroid-independent activation of androgen receptor in androgen-independent prostate cancer

1997 • 28 citations

Interleukin-1 activates protein kinase A and stimulates adrenocorticotropic hormone release from AtT-20 cells.

1993 • 26 citations

Calcium currents in a pituitary cell line (AtT-20): differential roles in stimulus-secretion coupling.

1996 • 25 citations

Corticotropin-releasing hormone excites adrenocorticotropin-secreting human pituitary adenoma cells by activating a nonselective cation current.

1996 • 22 citations

Pathophysiology of Cushing's disease.

1979 • 19 citations

Studies of the mechanisms of action of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in the ovine anterior pituitary: evidence that CRF and AVP stimulate protein phosphorylation and dephosphorylation

1994 • 17 citations

Corticotropin-releasing hormone stimulation of Ca2+ entry in corticotropes is partially dependent on protein kinase A

1995 • 15 citations

Interleukin-1 activates protein kinase A and stimulates adrenocorticotropic hormone release from AtT-20 cells

1993 • 13 citations

Calcium currents in a pituitary cell line (AtT-20): differential roles in stimulus-secretion coupling

1996 • 13 citations

Identification of cGMP-dependent protein kinase and its specific substrates in the anterior pituitary

1996 • 10 citations

Studies on Hypothalamo-Pituitary Corticoliberin System. IV. Quantitative Changes in ACTH-immunoreactive Anterior Pituitary Cells Evoked by Long-Term Intraventricular CRF Administration and Adrenalectomy¹)

2009 • 9 citations