Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Conserved Structures and Diversity of Functions of RNA-Binding Proteins

1994 • 1,873 citations

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

Resolution of phase ambiguity in macromolecular crystallography

1985 • 1,040 citations

Crystal structure at 1.92 Å resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

1994 • 827 citations

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

1992 • 825 citations

RIBBONS 2.0

1991 • 814 citations

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

1992 • 724 citations

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

1993 • 663 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

1992 • 619 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway

1995 • 529 citations

A nuclear localization domain in the hnRNP A1 protein.

1995 • 510 citations

RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing.

1994 • 481 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

1994 • 321 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

RNA recognition: A family matter?

1993 • 253 citations

RNA binding specificity of hnRNP proteins: a subset bind to the 3′ end of introns.

1988 • 251 citations

Specificity of ribonucleoprotein interaction determined by RNA folding during complex formation

1996 • 245 citations

Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains.

1993 • 243 citations

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

1993 • 241 citations

General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.

1992 • 241 citations

An RNA chaperone activity of non-specific RNA binding proteins in hammerhead ribozyme catalysis.

1994 • 234 citations

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

1991 • 218 citations

Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 211 citations

RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.

1991 • 196 citations

Functional domains of the human splicing factor ASF/SF2.

1993 • 188 citations

Interaction of the RNA-binding domain of the hnRNP C proteins with RNA.

1992 • 186 citations

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

1994 • 186 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

hnRNP A1 Selectively Interacts Through its Gly-rich Domain with Different RNA-binding Proteins

1996 • 179 citations

Mammalian heterogeneous nuclear ribonucleoprotein complex protein A1. Large-scale overproduction in Escherichia coli and cooperative binding to single-stranded nucleic acids.

1988 • 170 citations

Nucleo-cytoplasmic distribution of human hnrnp proteins: a search for the targeting domains in hnrnp a1

1995 • 158 citations

The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins.

1994 • 155 citations

RNA annealing activities in HeLa nuclei.

1994 • 148 citations

Differential Binding of Heterogeneous Nuclear Ribonucleoproteins to mRNA Precursors prior to Spliceosome Assembly In Vitro

1992 • 142 citations

Multiple RNA binding domains (RBDs) just don't add up

1995 • 139 citations

Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.

1990 • 139 citations

Renaturation of complementary DNA strands mediated by purified mammalian heterogeneous nuclear ribonucleoprotein A1 protein: implications for a mechanism for rapid molecular assembly.

1990 • 139 citations

The Xenopus laevis poly(A) binding protein is composed of multiple functionally independent RNA binding domains.

1990 • 131 citations

Proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins

1992 • 125 citations

Studies of the strand-annealing activity of mammalian hnRNP complex protein A1

1990 • 114 citations

Heterogeneous nuclear ribonucleoprotein A1 catalyzes RNA.RNA annealing.

1992 • 98 citations

Phosphorylation of human hnRNP protein A1 abrogatesin vitrostrand annealing activity

1993 • 91 citations

Identification of Heterogeneous Ribonucleoprotein A1 as a Novel Substrate for Protein Kinase C ζ

1995 • 85 citations

Amino acid sequence of the UP1 calf thymus helix-destabilizing protein and its homology to an analogous protein from mouse myeloma.

1985 • 82 citations

Interactions of the A1 heterogeneous nuclear ribonucleoprotein and its proteolytic derivative, UP1, with RNA and DNA: Evidence for multiple RNA binding domains and salt-dependent binding mode transitions

1991 • 78 citations

Both RNA-Binding Domains in Heterogeneous Nuclear Ribonucleoprotein A1 Contribute Toward Single-Stranded-RNA Binding

1994 • 64 citations

Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine:histone-arginine N-methyltransferase.

1994 • 63 citations

Ribonucleoproteins package 700 nucleotides of pre-mRNA into a repeating array of regular particles.

1988 • 62 citations

Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro.

1992 • 56 citations

Mammalian heterogeneous nuclear ribonucleoprotein A1. Nucleic acid binding properties of the COOH-terminal domain.

1990 • 53 citations

Mammalian Heterogeneous Ribonucleoprotein A1 and its Constituent Domains

1993 • 52 citations

Resonance Assignments and Solution Structure of the Second RNA-Binding Domain of Sex-lethal Determined by Multidimensional Heteronuclear Magnetic Resonance

1994 • 50 citations

Interaction of hnRNP A1 with snRNPs and pre-mRNAs: evidence for a possible role of A1 RNA annealing activity in the first steps of spliceosome assembly

1992 • 49 citations

Regulation of in vitro nucleic acid strand annealing activity of heterogeneous nuclear ribonucleoprotein protein A1 by reversible phosphorylation

1994 • 49 citations

Origins of Binding Specificity of the A1 Heterogeneous Nuclear Ribonucleoprotein

1996 • 44 citations

Determination of the Secondary Structure and Folding Topology of an RNA Binding Domain of Mammalian hnRNP A1 Protein Using Three-Dimensional Heteronuclear Magnetic Resonance Spectroscopy

1994 • 38 citations

Exon skipping by overexpression of a Drosophila heterogeneous nuclear ribonucleoprotein in vivo.

1995 • 21 citations

Acceleration of RNA renaturation by nucleic acid unwinding proteins.

1975 • 17 citations

Solar systems in the making

1990 • 12 citations

Crystallization and preliminary X-ray diffraction studies of UP1, the two-RRM domain of hnRNP A1

1997 • 4 citations