Minireview opiates, opioid peptides and single neurones

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

Electric current flow in excitable cells

1976 • 1,353 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

Excitatory synaptic mechanisms

1971 • 666 citations

Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section

1976 • 642 citations

Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons

1977 • 474 citations

Noradrenergic neurons: Morphine inhibition of spontaneous activity

1974 • 433 citations

Autoradiographic localization of the opiate receptor in rat brain

1975 • 387 citations

Naloxone as a GABA antagonist: Evidence from iontophoretic, receptor binding and convulsant studies

1978 • 330 citations

The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat

1976 • 321 citations

Iontophoretic application of opiates to the locus coeruleus

1977 • 287 citations

The regional distribution of a morphine-like factor enkephalin in monkey brain

1976 • 266 citations

Actions of glutamic acid on spinal neurones

1973 • 234 citations

Drug antagonism and pAx.

1957 • 207 citations

Depressive effects of morphine upon lamina V cells activities in the dorsal horn of the spinal cat

1975 • 198 citations

SUPPRESSION OF TRANSMISSION OF NOCICEPTIVE IMPULSES BY MORPHINE: SELECTIVE EFFECTS OF MORPHINE ADMINISTERED IN THE REGION OF THE SUBSTANTIA GELATINOSA

1977 • 195 citations

Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides

1977 • 193 citations

Morphine, enkephalin and the substantia gelatinosa

1976 • 188 citations

Differential effects of morphine on responses of dorsal horn lamina V type cells elicited by A and C fibre stimulation in the spinal cat

1976 • 185 citations

Characteristics and functions of opioids

1980 • 183 citations

Theories of drug antagonism.

1957 • 181 citations

Physiology of autonomic ganglia

1973 • 180 citations

Neurophysiologic studies in tissue culture

1976 • 179 citations

Specific-Opiate-Induced Depression of Transmitter Release from Dorsal Root Ganglion Cells in Culture

1978 • 163 citations

Iontophoresis and transmitter mechanisms in the mammalian central nervous system

1979 • 158 citations

Effects induced by stimulation of the centralis inferior nucleus of the raphe on dorsal horn interneurons in cat's spinal cord

1977 • 158 citations

Opiate Peptide Modulation of Amino Acid Responses Suggests Novel Form of Neuronal Communication

1978 • 158 citations

To spritz or not to spritz: The doubtful value of aimless iontophoresis

1974 • 155 citations

Enkephalin-Induced Depression of Single Neurons in Brain Areas with Opiate Receptors—Antagonism by Naloxone

1976 • 150 citations

Lamina-specific Suppression of Dorsal-horn Unit Activity by Morphine Sulfate

1974 • 150 citations

Effects of morphine and haloperidol on the electrical activity of rat nigrostriatal neurons.

1977 • 149 citations

Effects of Morphine and Naloxone on Dorsal Horn Neurones in the Cat

1974 • 143 citations

PHYSICAL TECHNIQUES IN BIOLOGICAL RESEARCH

1963 • 143 citations

Nerve and muscle cells in culture

1975 • 141 citations

Somatic stimuli, spinal pathways, and size of cutaneous fibers influencing unit activity in the medial medulary reticular formation

1969 • 140 citations

ENKEPHALINS AND DORSAL HORN NEURONES OF THE CAT: EFFECTS ON RESPONSES TO NOXIOUS AND INNOCUOUS SKIN STIMULI

1977 • 138 citations

THE EXCITATION OF SPINAL NEURONES BY THE IONOPHORETIC APPLICATION OF AGENTS WHICH CHELATE CALCIUM

1960 • 135 citations

Effects of microiontophoretically applied methionine-enkephalin on single neurones in rat brainstem

1976 • 135 citations

THE MECHANISM OF ACTION OF NARCOTIC ANALGESICS IN THE GUINEA‐PIG ILEUM

1977 • 130 citations

The nucleus reticularis gigantocellularis of the medulla oblongata is a highly sensitive site in the production of morphine analgesia in the rat

1977 • 124 citations

Response of medullary raphe neurons to peripheral stimulation and to systemic opiates

1977 • 121 citations

ACTIONS OF DRUGS ON SINGLE NEURONES IN THE CEREBRAL CORTEX

1965 • 118 citations

Mouse spinal cord in cell culture. III. Neuronal chemosensitivity and its relationship to synaptic activity

1977 • 112 citations

Iontophoresis of methionine-enkephalin in the locus coeruleus area

1977 • 109 citations

Effect of synaptic transmission blockade on morphine action in the guinea-pig myenteric plexus.

1976 • 105 citations

Somatosensory Responses of Bulboreticular Units in Awake Cat: Relation to Escape-Producing Stimuli

1971 • 100 citations

Enkephalin-induced inhibition of cortical neurones and the lack of this effect in morphine tolerant/dependent rats

1976 • 97 citations

Effects of enkephalin and morphine on Renshaw cells in feline spinal cord

1976 • 97 citations

Effects of methionine-enkephalin and leucine-enkephalin compared with those of morphine on brainstem neurones in cat

1976 • 94 citations

Depression of nociceptive and other neurones in the brain by iontophoretically applied met-enkephalin

1976 • 87 citations

Actions of opiates upon single unit activity in the cortex of naive and tolerant rats

1976 • 86 citations

MORPHINE AND NEUROTRANSMITTER SUBSTANCES: MICROIONTOPHORETIC STUDY IN THE RAT BRAIN STEM

1974 • 85 citations

Differential excitatory and inhibitory effects of opiates on non-nociceptive and nociceptive neurones in the spinal cord of the cat

1978 • 81 citations

Composition and Structure of Protein Bodies and Spherosomes Isolated from Ungerminated Seeds of Sorghum bicolor (Linn.) Moench

1975 • 79 citations

Mouse spinal cord in cell culture. II. Synaptic activity and circuit behavior

1977 • 79 citations

Effects of morphine upon the lamina V type cells activities in the dorsal horn of the decerebrate cat

1976 • 78 citations

Enkephalin and substance P effects related to trigeminal pain

1978 • 76 citations

Effects of opiate agonists and antagonists on central neurons of the cat.

1976 • 72 citations

Enkephalin inhibits firing of myenteric neurones

1976 • 72 citations

Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats

1974 • 68 citations

Morphine Blockade of Amino Acid Putative Transmitters on Cat Spinal Cord Sensory Interneurones

1973 • 66 citations

Medial bulboreticular response to peripherally applied noxious stimuli

1974 • 62 citations

Drugs and Central Synaptic Transmission

1976 • 62 citations

Morphine: Ability to block neuronal activity evoked by a nociceptive stimulus

1976 • 59 citations

Opiate tolerance and dependence induced in vitro in single myenteric neurones

1978 • 57 citations

Unit activity of amygdala and hippocampal neurons: Effects of morphine and benzodiazepines

1977 • 57 citations

Reciprocal (push-pull) effects of morphine on single units in the ventromedian and lateral hypothalamus and influences on other nuclei: with a comment on methadone effects during withdrawal from morphine

1974 • 57 citations

Effects of narcotic opiates and serotonin on the electrical behavior of neurons in the guinea pig myenteric plexus

1974 • 52 citations

Opiate agonist-antagonist effects on Renshaw cells and spinal interneurones

1974 • 51 citations

Extracellular recording from the guinea-pig myenteric plexus and the action of morphine

1977 • 51 citations

Substance P and opiate receptors

1977 • 47 citations

Evoked bulbar reticular unit activity following delta fiber stimulation of peripheral somatosensory nerve in cat

1972 • 46 citations

PHARMACOLOGICAL PROPERTIES OF ELECTRICAL ACTIVITIES OBTAINED FROM NEURONS IN AUERBACH’S PLEXUS

1973 • 45 citations

Morphine and the synaptic activation of Renshaw cells

1972 • 41 citations

Effects of morphine and naloxone on renshaw cells and spinal interneurones in morphine dependent and non-dependent rats

1976 • 41 citations

Morphine, naloxone and the responses of medial thalamic neurones of the cat

1977 • 40 citations

Morphine and enkephalin interactions with putative neurotransmitters in rat hippocampus

1977 • 40 citations

Single neuron studies of opiate action in the guinea pig myenteric plexus

1975 • 40 citations

Action of morphine on guinea-pig myenteric plexus and mouse vas deferens studied by intracellular recording

1975 • 37 citations

The effects of morphine, etorphine and sinomenine on the chemical sensitivity and synaptic responses of Renshaw cells and other spinal neurones in the rat

1974 • 31 citations

Opiate withdrawal signs in single myenteric neurones

1978 • 30 citations

Effect of etorphine, morphine and diprenorphine on neurones of the cerebral cortex and spinal cord of the rat

1972 • 25 citations

Effect of morphine on a depolarising dopamine response

1975 • 25 citations

Stereoscpecific actions of morphine on single neurones in the brain stem of the rat

1977 • 25 citations

Morphine Excitation in the Cerebral Cortex

1975 • 24 citations

EFFECTS OF ACETYLCHOLINE RELEASING DRUGS ON ELECTRICAL ACTIVITIES OBTAINED FROM AUERBACH'S PLEXUS IN THE GUINEA PIG ILEUM

1974 • 22 citations

Non-specific effects of morphine-like drugs

1969 • 19 citations

The depression of thalamic nociceptive neurones by D-ala2,D-leu5-enkephalin

1978 • 19 citations

Modes and Sites of “Analgesic” Action of Anesthetics on the Spinal Cord

1975 • 12 citations

Morphine fails to block the discharges evoked by intra-arterial bradykinin in dorsal horn neurones of spinal cats

1977 • 12 citations

VA Given Task of Developing Programs for GI Addicts

1971 • 4 citations