Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy

Reporting results of cancer treatment

1981 • 7,916 citations

Cancer statistics, 1997

1997 • 2,045 citations

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate

1974 • 619 citations

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

1994 • 585 citations

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

1994 • 416 citations

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival.

1996 • 347 citations

Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction.

1992 • 248 citations

Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer.

1995 • 197 citations

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.

1994 • 191 citations

Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial

1995 • 130 citations

Regional chemotherapy for hepatic metastases of colorectal carcinoma (continuous intraarterialversus continuous intraarterial/intravenous therapy). Results of a controlled clinical trial

1989 • 100 citations

The mutational status of p53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents

1995 • 91 citations

Colorectal cancer biology: clinical implications.

1995 • 37 citations

Colorectal cancer: hepatic-directed therapy--the role of surgery, regional chemotherapy, and novel modalities.

1995 • 30 citations

Treatment of colorectal cancer metastases confined to the liver

1995 • 26 citations

Regional chemotherapy directed by individual chemosensitivity testing in vitro: a prospective decision-aiding trial.

1996 • 24 citations

Long-term survivors of colorectal cancer with unresectable hepatic metastases

1985 • 17 citations