Ternary Complex Factors Elk-1 and Sap-1a Mediate Growth Hormone-Induced Transcription of Egr-1 (Early Growth Response Factor-1) in 3T3-F442A Preadipocytes

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.

1995 • 667 citations

Activation of ternary complex factor Elk-1 by MAP kinases.

1993 • 561 citations

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.

1993 • 543 citations

A dual effector theory of growth-hormone action

1985 • 512 citations

Role of p38 and JNK Mitogen-Activated Protein Kinases in the Activation of Ternary Complex Factors

1997 • 467 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

PPARγ induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A

1997 • 379 citations

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

1990 • 343 citations

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.

1987 • 292 citations

Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line

1979 • 282 citations

Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte Differentiation

1997 • 272 citations

Mechanism of signaling by growth hormone receptor

1996 • 264 citations

Growth hormone and the adipose conversion of 3T3 cells

1982 • 254 citations

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

1997 • 226 citations

Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements.

1990 • 218 citations

Regulation of theXmyf-5andXmyoDExpression Pattern during Early Xenopus Development

1998 • 211 citations

Ionizing radiation activates transcription of the EGR1 gene via CArG elements.

1992 • 200 citations

The fos Oncogene

1987 • 196 citations

The Generation of Insulin-Like Growth Factor-1—Sensitive Cells by Growth Hormone Action

1986 • 192 citations

Functional serum response elements upstream of the growth factor-inducible gene zif268.

1989 • 180 citations

Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.

1994 • 171 citations

Casein kinase II phosphorylation increases the rate of serum response factor-binding site exchange.

1992 • 165 citations

5' flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene

1988 • 158 citations

Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.

1996 • 155 citations

Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain.

1995 • 145 citations

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion.

1992 • 140 citations

Growth hormone regulation of the expression of differentiation-dependent genes in preadipocyte Ob1771 cells

1986 • 131 citations

The Zinc Finger Transcription Factor Egr-1 Potentiates Macrophage Differentiation of Hematopoietic Cells

1995 • 120 citations

Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP.

1996 • 120 citations

Ras/MAP kinase-dependent and -independent signaling pathways target distinct ternary complex factors.

1994 • 113 citations

Contribution of Growth Hormone to the Adipogenic Activity of Serum*

1984 • 112 citations

An inducible nuclear factor binds to a growth hormone-regulated gene.

1990 • 109 citations

FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements

1997 • 107 citations

Role of EGR-1 in Thapsigargin-Inducible Apoptosis in the Melanoma Cell Line A375-C6

1995 • 107 citations

Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation.

1991 • 98 citations

Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter.

1994 • 96 citations

Activation of the Sap-1a Transcription Factor by the c-Jun N-terminal Kinase (JNK) Mitogen-activated Protein Kinase

1997 • 86 citations

SAP1a is a nuclear target of signaling cascades involving ERKs.

1995 • 86 citations

Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta.

1995 • 86 citations

Determinants of DNA-Binding Specificity of ETS-Domain Transcription Factors

1996 • 82 citations

Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both proliferating and terminally differentiated myeloid cells.

1989 • 81 citations

Suppression of v-sis-dependent transformation by the transcription factor, Egr-1.

1994 • 75 citations

A Ternary Complex Factor-Dependent Mechanism Mediates Induction of egr-1 through Selective Serum Response Elements following Antigen Receptor Cross-Linking in B Lymphocytes

1995 • 72 citations

The serum response element can mediate induction of c-fos by growth hormone.

1993 • 70 citations

Growth Hormone Regulates Ternary Complex Factors and Serum Response Factor Associated with the c-fos Serum Response Element

1997 • 70 citations

EGR-1 Induction Is Required for Maximal Radiosensitivity in A375-C6 Melanoma Cells

1996 • 69 citations

A STAT Factor Mediates the Sexually Dimorphic Regulation of Hepatic Cytochrome P450 3A10/Lithocholic Acid 6β-Hydroxylase Gene Expression by Growth Hormone

1995 • 65 citations

Properties of growth hormone receptors in relation to the adipose conversion of 3T3 cells

1983 • 55 citations

PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements

1993 • 48 citations

Growth hormone and adipose differentiation: growth hormone-induced antimitogenic state in 3T3-F442A preadipose cells.

1990 • 45 citations

Transactivation of the rat CYP2C13 gene promoter involves HNF-1, HNF-3, and members of the orphan receptor subfamily

1994 • 38 citations

Growth hormone and colony-stimulating factor 1 share multiple response elements in the c-fos promoter.

1995 • 36 citations

Characterization of cis-Acting Sequences and trans-Acting Signals Regulating Early Growth Response 1 and c-fos Promoters Through the Granulocyte-Macrophage Colony-Stimulating Factor Receptor in BA/F3 Cells

1997 • 35 citations

The transcription factor, Egr-1, is rapidly modulated in response to retinoic acid in P19 embryonal carcinoma cells

1991 • 35 citations

Regulation of Glucose Transport and c-fos and egr-1 Expression in Cells with Mutated or Endogenous Growth Hormone Receptors*

1998 • 34 citations

Response of fat cells to growth hormone (GH): effect of long term treatment with recombinant human GH in GH-deficient adults.

1994 • 33 citations

Growth Hormone-Dependent Events in the Adipose Differentiation of 3T3-F442A Fibroblasts: Modulation of Macromolecular Synthesis*

1989 • 31 citations

Simultaneous Activation of p90rsk and p70s6k S6 Kinases by Growth Hormone in 3T3-F442A Preadipocytes

1993 • 31 citations

Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta

1995 • 28 citations

The first disulphide loop of the rabbit growth hormone receptor is required for binding to the hormone

1992 • 24 citations

Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements.

1992 • 23 citations

Activation of early growth response 1 gene transcription and pp90rsk during induction of monocytic differentiation.

1994 • 18 citations

Effect of human growth hormone and insulin on [3H]thymidine incorporation, cell cycle progression, and cyclin D expression in 3T3-F442A preadipose cells.

1995 • 16 citations

Hormonal requirements for growth and differentiation of ob17 preadipocyte cells in vitro.

1983 • 13 citations

Physiology of the fat cell, with emphasis on the role of growth hormone.

1992 • 11 citations