Apoptosis detection: an overview

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Apoptosis by Death Factor

1997 • 5,038 citations

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1994 • 2,450 citations

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1994 • 1,969 citations

Life, death, and the pursuit of apoptosis.

1996 • 1,333 citations

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1995 • 1,179 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

JC‐1, but not DiOC₆(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

1997 • 982 citations

Apoptosis and disease

1993 • 684 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry

1992 • 542 citations

Comparative evaluation of several DNA binding dyes in the detection of apoptosis‐associated chromatin degradation by flow cytometry

1992 • 375 citations

Factors influencing DNA migration from individual cells subjected to gel electrophoresis

1992 • 370 citations

Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma.

1996 • 360 citations

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1994 • 320 citations

Nuclease detection in SDS-polyacrylamide gel electrophoresis

1977 • 291 citations

Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections.

1993 • 276 citations

Rapidin VivoEffects of Glucocorticoids on the Integrity of Rat Lymphocyte Genomic Deoxyribonucleic Acid*

1986 • 218 citations

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

1984 • 207 citations

Technical tips

1994 • 192 citations

A simple and repid method for detection of apoptosis in human cells

1992 • 163 citations

Techniques in apoptosis: A user's guide

1997 • 134 citations

Detection and characterization of apoptotic peripheral blood lymphocytes in human immunodeficiency virus infection and cancer chemotherapy by a novel flow immunocytometric method

1994 • 117 citations

Analysis of TNF alpha-induced DNA strand breaks at the single cell level.

1991 • 111 citations

Techniques in apoptosis

1996 • 92 citations

The comet assay: A new method to examine heterogeneity associated with solid tumors

1998 • 82 citations

An improved method for the detection of DNA fragmentation

1991 • 82 citations

Techniques in Apoptosis: A User's Guide.

1997 • 79 citations

Similar Actions of Glucocorticoids and Calcium on the Regulation of Apoptosis in S49 Cells

1991 • 74 citations

Internucleosomal Deoxyribonucleic Acid Cleavage Activity in Apoptotic Thymocytes: Detection and Endocrine Regulation*

1991 • 61 citations

A simple fluorescence method for surface antigen phenotyping of lymphocytes undergoing DNA fragmentation

1992 • 60 citations

Regulation of apoptosis resistance and ontogeny of age-dependent diseases

1997 • 53 citations

Development of an Apoptosis Endonuclease Assay

1991 • 33 citations

Application of confocal scanning laser microscopy in experimental pathology

1991 • 26 citations

Simultaneous in situ detection of mRNA and apoptotic cells by combined hybridization and TUNEL.

1996 • 18 citations

An Image Analysis Workstation Designed for Multiple Users: Application of Quantitative Digital Imaging Techniques to Electron Microscopy

1992 • 6 citations