The Wnt/β-Catenin Pathway Posteriorizes Neural Tissue in Xenopus by an Indirect Mechanism Requiring FGF Signalling

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

Normal table of Xenopus laevis (Daudin)

1995 • 2,955 citations

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

Early development of Xenopus laevis : a laboratory manual

2000 • 1,204 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

1996 • 1,156 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

1997 • 1,098 citations

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

1999 • 823 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum

1992 • 579 citations

A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus

1997 • 527 citations

Initiation of neural induction by FGF signalling before gastrulation

2000 • 519 citations

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1994 • 484 citations

Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.

1993 • 449 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis

1991 • 373 citations

Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development

1999 • 338 citations

An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo

2000 • 326 citations

Activation and organization of the central nervous system in amphibians. Part I. Induction and activation

1952 • 319 citations

The status of Wnt signalling regulates neural and epidermal fates in the chick embryo

2001 • 315 citations

Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development

1996 • 291 citations

Caudalization of neural fate by tissue recombination and bFGF

1995 • 290 citations

Cephalic expression and molecular characterization of Xenopus En-2

1991 • 289 citations

Initiation of Rhombomeric Hoxb4 Expression Requires Induction by Somites and a Retinoid Pathway

1998 • 275 citations

Dorsalization and neural induction: properties of the organizer in Xenopus laevis.

1983 • 267 citations

Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication

1994 • 267 citations

FGF-8Is Associated with Anteroposterior Patterning and Limb Regeneration inXenopus

1997 • 258 citations

A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction

1987 • 250 citations

LEF-1/TCF Proteins Mediate Wnt-Inducible Transcription from the Xenopus Nodal-Related 3 Promoter

1997 • 244 citations

An essential role for retinoid signaling in anteroposterior neural patterning

1997 • 236 citations

Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus

1997 • 224 citations

Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin

1995 • 222 citations

The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF

1990 • 220 citations

The structure and expression of the Xenopus Krox-20 gene: conserved and divergent patterns of expression in rhombomeres and neural crest

1993 • 220 citations

Cell interactions and the control of gene activity during early development of Xenopus laevis

1986 • 213 citations

Expression of Pax-3 in the Lateral Neural Plate Is Dependent on a Wnt-Mediated Signal from Posterior Nonaxial Mesoderm

1999 • 195 citations

Reprogramming Hox Expression in the Vertebrate Hindbrain: Influence of Paraxial Mesoderm and Rhombomere Transposition

1996 • 193 citations

Efficient Hormone-Inducible Protein Function in Xenopus laevis

1995 • 190 citations

Regional biosynthetic markers in the early amphibian embryo

1984 • 180 citations

Mechanism of anteroposterior axis specification in vertebrates Lessons from the amphibians

1992 • 179 citations

XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm

1998 • 163 citations

Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3

1997 • 158 citations

Convergent Inductive Signals Specify Midbrain, Hindbrain, and Spinal Cord Identity in Gastrula Stage Chick Embryos

1999 • 156 citations

Specification of the Zebrafish Nervous System by Nonaxial Signals

1997 • 137 citations

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction

1992 • 136 citations

Vertebrate Neural Induction: Inducers, Inhibitors, and a New Synthesis

1997 • 131 citations

Direct regulation of the Xenopus engrailed-2 promoter by the Wnt signaling pathway, and a molecular screen for Wnt-responsive genes, confirm a role for Wnt signaling during neural patterning in Xenopus

1999 • 129 citations

Neural Induction in the Absence of Mesoderm: β-Catenin-Dependent Expression of Secreted BMP Antagonists at the Blastula Stage in Xenopus

2001 • 126 citations

Analysis of competence and of Brachyury autoinduction by use of hormoneinducible Xbra

1997 • 121 citations

XenopusHindbrain Patterning Requires Retinoid Signaling

1997 • 118 citations

The C-terminal transactivation domain of β-catenin is necessary and sufficient for signaling by the LEF-1/β-catenin complex in Xenopus laevis

1999 • 112 citations

Assignment of Early Caudal Identity to Neural Plate Cells by a Signal from Caudal Paraxial Mesoderm

1997 • 106 citations

FGF Is Required for Posterior Neural Patterning but Not for Neural Induction

1999 • 104 citations

Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8.

1994 • 97 citations

Hox gene induction in the neural tube depends on three parameters: competence, signal supply and paralogue group

1997 • 92 citations

Ras-Mediated FGF Signaling Is Required for the Formation of Posterior but Not Anterior Neural Tissue in Xenopus laevis

2000 • 91 citations

Xwnt-8 and lithium can act upon either dorsal mesodermal or neurectodermal cells to cause a loss of forebrain in Xenopus embryos

1997 • 89 citations

Inducible gene expression in transgenic Xenopus embryos

2000 • 69 citations

Difference in XTcf-3 dependency accounts for change in response to β-catenin-mediated Wnt signalling inXenopusblastula

2001 • 63 citations

Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos

1992 • 53 citations

Mesoderm formation in Xenopus ectodermal explants overexpressing Xwnt8: evidence for a cooperating signal reaching the animal pole by gastrulation

1993 • 45 citations

Isolation and characterization of chicken β-catenin

1997 • 20 citations

Wholemount In Situ Hybridization to Xenopus Embryos

2008 • 9 citations