Genome-wide Mapping of RELA(p65) Binding Identifies E2F1 as a Transcriptional Activator Recruited by NF-κB upon TLR4 Activation

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

2006 • 4,019 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

Signalling pathways of the TNF superfamily: a double-edged sword

2003 • 2,602 citations

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

2006 • 2,414 citations

TRANSFAC(R): transcriptional regulation, from patterns to profiles

2003 • 2,010 citations

Inferences, questions and possibilities in Toll-like receptor signalling

2004 • 1,458 citations

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

2006 • 1,137 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

IL-23 promotes tumour incidence and growth

2006 • 968 citations

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1993 • 960 citations

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

1995 • 923 citations

A Cellular MicroRNA Mediates Antiviral Defense in Human Cells

2005 • 906 citations

Anti-inflammatory lipid mediators and insights into the resolution of inflammation

2002 • 831 citations

A Steroid Receptor Coactivator, SRA, Functions as an RNA and Is Present in an SRC-1 Complex

1999 • 788 citations

A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT

2005 • 712 citations

Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors

2005 • 634 citations

The IL-1 family and inflammatory diseases.

2004 • 597 citations

IL-23 plays a key role inHelicobacter hepaticus–induced T cell–dependent colitis

2006 • 570 citations

The E2F family: specific functions and overlapping interests

2004 • 521 citations

NF-κB Subunit-Specific Regulation of the Interleukin-8 Promoter

1993 • 504 citations

Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB

2004 • 382 citations

NF-kappa B subunit-specific regulation of the interleukin-8 promoter.

1993 • 369 citations

An algorithm for finding signals of unknown length in DNA sequences

2001 • 342 citations

The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells

2006 • 333 citations

Multiple Control Elements Mediate Activation of the Murine and Human Interleukin 12 p40 Promoters: Evidence of Functional Synergy between C/EBP and Rel Proteins

1997 • 310 citations

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome

2006 • 307 citations

Distribution of NF-κB-binding sites across human chromosome 22

2003 • 302 citations

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

2000 • 301 citations

E2F1 and c-Myc Potentiate Apoptosis through Inhibition of NF-κB Activity that Facilitates MnSOD-Mediated ROS Elimination

2002 • 282 citations

Relationships between p63 Binding, DNA Sequence, Transcription Activity, and Biological Function in Human Cells

2006 • 280 citations

Bay 11-7082 inhibits transcription factor NF-kappa B and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells

2002 • 276 citations

Interactions of NF-κB with chromatin: the art of being at the right place at the right time

2005 • 251 citations

Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins

2003 • 241 citations

The role of MIP-1α in Inflammation and hematopoiesis

1996 • 218 citations

Coordinated binding of NF-κB family members in the response of human cells to lipopolysaccharide

2006 • 174 citations

The IκB Kinase Complex and NF-κB Actas Master Regulators of Lipopolysaccharide-Induced Gene Expressionand Control Subordinate Activation ofAP-1

2004 • 145 citations

Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice

2001 • 130 citations

Identification of a TLR4‐ and TRIF‐dependent activation program of dendritic cells

2004 • 123 citations

Interferon Regulatory Factor-3-mediated Activation of the Interferon-sensitive Response Element by Toll-like receptor (TLR) 4 but Not TLR3 Requires the p65 Subunit of NF-κ

2003 • 113 citations

Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice

2003 • 85 citations

TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein.

1996 • 81 citations

Role of the Intronic Enhancer in Tumor Necrosis Factor-mediated Induction of Manganous Superoxide Dismutase

2003 • 73 citations

Interaction between Cell Cycle Regulator, E2F-1, and NF-κB Mediates Repression of HIV-1 Gene Transcription

1997 • 62 citations

Chronic Inflammation Promotes Retinoblastoma Protein Hyperphosphorylation and E2F1 Activation

2005 • 52 citations

Inhibition of NF-κB activation by a dominant-negative mutant of IκBα

1996 • 19 citations