Identification of Mutations in a Sindbis Virus Variant Able to Establish Persistent Infection in BHK Cells: The Importance of a Mutation in the nsP2 Gene

The alphaviruses: gene expression, replication, and evolution

1994 • 1,952 citations

A New Generation of Animal Cell Expression Vectors Based on the Semliki Forest Virus Replicon

1991 • 899 citations

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

1993 • 495 citations

Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants

1987 • 476 citations

In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release

1991 • 450 citations

Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells

1989 • 402 citations

Complete nucleotide sequence of the genomic RNA of Sindbis virus

1984 • 393 citations

Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs

1993 • 366 citations

Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis.

1994 • 311 citations

Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis

1994 • 301 citations

A novel superfamily of nucleoside triphosphate‐binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination

1988 • 282 citations

Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.

1995 • 250 citations

Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans

1989 • 229 citations

Alphavirus-based expression vectors: strategies and applications.

1996 • 224 citations

Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer

1996 • 194 citations

Sindbis virus infection of chick and hamster cells: Synthesis of virus-specific proteins

1969 • 166 citations

ATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2

1994 • 162 citations

Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells

1994 • 142 citations

Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein.

1994 • 136 citations

Nuclear localization of Semliki Forest virus-specific nonstructural protein nsP2

1990 • 134 citations

Complete nucleotide sequence of the nonstructural protein genes of Semliki Forest virus

1986 • 130 citations

Na+ and K+ concentrations and the regulation of protein synthesis in Sindbis virus-infected chick cells

1979 • 128 citations

Complete sequence of the genomic RNA of O'Nyong-Nyong virus and its use in the construction of alphavirus phylogenetic trees

1990 • 119 citations

Evidence that sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein

1989 • 116 citations

Nuclear and nucleolar targeting signals of semliki forest virus nonstructural protein nsP2

1992 • 99 citations

Viral determinants of age-dependent virulence of Sindbis virus for mice

1993 • 99 citations

A Plasmid-Based Self-Amplifying Sindbis Virus Vector

1995 • 96 citations

Genome sequences of a mouse-avirulent and a mouse-virulent strain of ross river virus

1988 • 90 citations

Functional Significance of the Nuclear-Targeting and NTP-Binding Motifs of Semliki Forest Virus Nonstructural Protein nsP2

1996 • 75 citations

Alphaviruses ? vectors for the expression of heterologous genes

1993 • 75 citations

Establishment and maintenance of persistent infection by Sindbis virus in BHK cells

1980 • 62 citations

Modification of membrane permeability by animal viruses

1989 • 60 citations

Genetic evidence that epizootic Venezuelan equine encephalitis (VEE) viruses may have evolved from enzootic VEE subtype I-D virus

1992 • 60 citations

Sindbis virus RNA-negative mutants that fail to convert from minus-strand to plus-strand synthesis: role of the nsP2 protein

1996 • 55 citations

Sequence analysis of cDNA's derived from the RNA of Sindbis virions and of defective interfering particles

1982 • 52 citations

Semliki Forest virus persistence in mouse L929 cells

1980 • 42 citations

Effects of anti-E2 monoclonal antibody on sindbis virus replication in AT3 cells expressing bcl-2

1995 • 40 citations

Defective interfering particles of Sindbis virus do not interfere with the homologous virus obtained from persistently infected BHK cells but do interfere with Semliki Forest virus

1981 • 37 citations

The role of monovalent cation transport in Sindbis virus maturation and release

1989 • 30 citations

ALIGNMENT SERVICE: creation and processing of alingments of sequences of unlimited length

1995 • 23 citations

Effect of tunicamycin on the development of the cytopathic effect in Sindbis virus-infected avian fibroblasts

1985 • 19 citations

Sequencing two DNA templates in five channels by digital compression.

1993 • 7 citations

[Primary structure of proteins of the nsP2 and nsP3 polymerase complex confirm the recombinant nature of western encephalitis virus].

1994 • 4 citations

[The effect of Sindbis virus multiplication on gene expression of host cells].

1994 • 1 citations