Involvement of the choroid plexus in central nervous system inflammation

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 837 citations

CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice

1999 • 678 citations

Tight junctions of the blood-brain barrier.

2000 • 490 citations

Claudin-11/OSP-based Tight Junctions of Myelin Sheaths in Brain and Sertoli Cells in Testis

1999 • 434 citations

Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1995 • 381 citations

Time course and localization patterns of interleukin-1β messenger rna expression in brain and pituitary after peripheral administration of lipopolysaccharide

1998 • 323 citations

Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations

1999 • 313 citations

Regulation of the Genes Encoding Interleukin‐6, Its Receptor, and gp130 in the Rat Brain in Response to the Immune Activator Lipopolysaccharide and the Proinflammatory Cytokine Interleukin‐1β

1997 • 312 citations

Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1983 • 295 citations

Effect of Acute Systemic Inflammatory Response and Cytokines on the Transcription of the Genes Encoding Cyclooxygenase Enzymes (COX‐1 and COX‐2) in the Rat Brain

1998 • 279 citations

Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states.

1998 • 262 citations

Age-related effects of interleukin-1 beta on polymorphonuclear neutrophil-dependent increases in blood-brain barrier permeability in rats

1997 • 244 citations

Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat

1999 • 244 citations

ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro.

1996 • 238 citations

The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system

1996 • 235 citations

Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes.

1993 • 234 citations

Expression of complement in the brain: role in health and disease

1996 • 233 citations

Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats

1997 • 233 citations

Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse.

1994 • 216 citations

Lymphocyte Targeting of the Central Nervous System: A Review of Afferent and Efferent CNS‐Immune Pathways

1996 • 210 citations

The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin.

1998 • 204 citations

Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.

1992 • 156 citations

CCR5 Δ32, matrix metalloproteinase-9 and disease activity in multiple sclerosis

2000 • 154 citations

Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro

2000 • 143 citations

Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro.

1990 • 140 citations

Regulation of the Gene Encoding Tumor Necrosis Factor Alpha (TNF-α) in the Rat Brain and Pituitary in Response to Different Models of Systemic Immune Challenge

1999 • 140 citations

Mechanics of resting isolated single vascular smooth muscle cells from bovine coronary artery

1984 • 129 citations

Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus.

1992 • 126 citations

Organization of choroid plexus epithelial and endothelial cell tight junctions and regulation of claudin-1, -2 and -5 expression by protein kinase C

2000 • 121 citations

Localization of Interleukin 1 Type I Receptor mRNA in Rat Brain

1994 • 119 citations

Tight junctions in the choroid plexus epithelium. A freeze-fracture study including complementary replicas.

1979 • 118 citations

Expression and localization of p80 and p68 interleukin-1 receptor proteins in the brain of adult mice

1999 • 118 citations

HIV Infection of Human Choroid Plexus

1995 • 115 citations

Differential Expression of ICAM-1, VCAM-1 and Their Ligands LFA-1, Mac-1, CD43, VLA-4, and MHC Class II Antigens in MurineToxoplasmaEncephalitis: A Light Microscopic and Ultrastructural Immunohistochemical Study

1994 • 110 citations

Origin, nature, and some functional considerations of intraventricular macrophages, with special reference to the epiplexus cells

1998 • 107 citations

Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain.

1997 • 102 citations

Functional capacity of solid tissue transplants in the brain: evidence for immunological privilege

1985 • 102 citations

Regulation of lymphocyte homing into the brain during viral encephalitis at various stages of infection.

1996 • 97 citations

Differential expression of individual complement regulators in the brain and choroid plexus.

1999 • 96 citations

Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: An indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier

1993 • 95 citations

HLA-DR-positive dendritic cells of the normal human choroid plexus: A potential reservoir of HIV in the central nervous system

1998 • 91 citations

In vivo and in vitro formation of the junctional complex in choroid epithelium

1977 • 87 citations

Choroid plexus recovery after transient forebrain ischemia: role of growth factors and other repair mechanisms.

2000 • 85 citations

Temporal and spatial patterns ofc-fos mRNA induced by intravenous interleukin-1: A cascade of non-neuronal cellular activation at the blood-brain barrier

1998 • 85 citations

Ultrastructural localization of adhesion molecules in the healthy

1999 • 84 citations

Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis

1996 • 80 citations

Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1

1995 • 78 citations

Immunological function of the blood-cerebrospinal fluid barrier.

1989 • 76 citations

Adhesion molecule phenotype of T lymphocytes in inflamed CNS

1998 • 61 citations

Antigen-specific damage to brain vascular endothelial cells mediated by encephalitogenic and nonencephalitogenic CD4+ T cell lines in vitro.

1990 • 59 citations

Mitochondrial content of choroid plexus epithelium

1997 • 58 citations

Choroiditis and meningitis in experimental murine infection withListeria monocytogenes

1992 • 56 citations

The choroid plexus of the mature and aging rat: The choroidal epithelium

1979 • 45 citations

Activated T-lymphocytes express occludin, a component of tight junctions.

1998 • 44 citations

Rat Interleukin-1 β Binding Sites in Rat Hypothalamus and Pituitary Gland

1995 • 41 citations

Expression of E-Selectin, P-Selectin, and Intercellular Adhesion Molecule-1 during Experimental Murine Listeriosis

1999 • 39 citations

Changes in the choroid plexus, responses by intrinsic epiplexus cells and recruitment from monocytes after experimental head acceleration injury in the non-human primate

1992 • 38 citations

Cerebral endothelial cells are a major source for soluble intercellular adhesion molecule-1 in the human central nervous system

1995 • 37 citations

Up-regulation of intercellular adhesion molecule 1 in cerebral microvessels after cortical contusion trauma in a rat model

1997 • 29 citations

Three-dimensional and ultrastructural ICAM-1 distribution in the choroid plexus, arachnoid membrane and dural sinus of inflammatory rats induced by LPS injection in the lateral ventricles

1998 • 26 citations

Bacterial endotoxin-induced gene expression in the choroid plexus and paraventricular and supraoptic hypothalamic nuclei of the sheep

1996 • 26 citations

Trafficking of activated cytotoxic T lymphocytes into the central nervous system: Use of a transgenic model

1993 • 24 citations

Interleukin-1 Receptor Accessory Protein Transcripts in the Brain and Spleen: Kinetics after Peripheral Administration of Bacterial Lipopolysaccharide in Mice

1996 • 24 citations

Coexpression of Class I Major Histocompatibility Antigen and Viral RNA in Central Nervous System of Mice Infected With Theiler's Virus: A Model for Multiple Sclerosis

1992 • 23 citations

MURINE INFLUENZA VIRUS ENCEPHALOMYELITIS

1973 • 23 citations

Adhesion Molecules and Chemokines in Lymphocyte Trafficking

1997 • 19 citations

Up-regulation of surface antigens on epiplexus cells in postnatal rats following intraperitoneal injections of lipopolysaccharide

1994 • 19 citations

Ultrastructural aspects of the choroid plexus epithelium as revealed by the rapid-freezing and deep-etching techniques

1985 • 16 citations

Infection of choroid plexus cells by human T cell leukaemia virus type I.

1997 • 9 citations

Pathological alterations of ependyma and choroid plexus after experimental cerebral infection of mice with Sendai virus

1979 • 9 citations

Intrathecal release of sICAM-1 into CSF in neuroborreliosis — increased brain-derived fraction

2000 • 7 citations

The circumventricular organs are involved in inflammation in the central nervous system

1998 • 1 citations