Toll-like receptors stimulate human neutrophil function

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

A Toll-like receptor recognizes bacterial DNA

2000 • 6,348 citations

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

2001 • 5,893 citations

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

2001 • 3,507 citations

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

2002 • 2,438 citations

Host Defense Mechanisms Triggered by Microbial Lipoproteins Through Toll-Like Receptors

1999 • 1,679 citations

Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2

1999 • 1,500 citations

Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

1998 • 1,443 citations

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

1999 • 1,381 citations

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

2008 • 1,268 citations

Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

1998 • 1,249 citations

Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

2000 • 1,173 citations

Differential Expression and Regulation of Toll-Like Receptors (TLR) in Human Leukocytes: Selective Expression of TLR3 in Dendritic Cells

2000 • 1,060 citations

Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

2003 • 789 citations

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

2002 • 724 citations

Toll-like receptors: key mediators of microbe detection

2002 • 689 citations

Cutting Edge: Inflammatory Signaling byBorrelia burgdorferiLipoproteins Is Mediated by Toll-Like Receptor 2

1999 • 666 citations

Release of Inflammatory Mediators from Stimulated Neutrophils

1980 • 649 citations

Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway

2000 • 584 citations

The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells

2003 • 399 citations

Regulation of neutrophil-derived chemokine expression by IL-10.

1994 • 347 citations

Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors.

1990 • 325 citations

Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils.

1999 • 308 citations

Role of Toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils

2002 • 303 citations

IMMUNITY IN INFECTIVE DISEASES

1906 • 282 citations

Cytokine-induced neutrophil-derived interleukin-8.

1992 • 260 citations

Ph+ acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

2002 • 259 citations

Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors

2003 • 256 citations

Gene Expression and Production of the Monokine Induced by IFN-γ (MIG), IFN-Inducible T Cell α Chemoattractant (I-TAC), and IFN-γ-Inducible Protein-10 (IP-10) Chemokines by Human Neutrophils

1999 • 244 citations

The Human Neutrophil Respiratory Burst Oxidase

1990 • 225 citations

Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1 alpha.

1993 • 207 citations

IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucyl-phenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway.

1992 • 176 citations

Activation of the Neutrophil Respiratory Burst Oxidase

1999 • 174 citations

The Chemokine Macrophage-Inflammatory Protein-1α and Its Receptor CCR1 Control Pulmonary Inflammation and Antiviral Host Defense in Paramyxovirus Infection

2000 • 165 citations

Phenotypic and functional change of cytokine-activated neutrophils: inflammatory neutrophils are heterogeneous and enhance adaptive immune responses

2001 • 161 citations

Regulation of neutrophil interleukin 8 gene expression and protein secretion by LPS, TNF‐α, and IL‐1β

1993 • 149 citations

Neutrophils produce biologically active macrophage inflammatory protein-3α (MIP-3α) / CCL20 and MIP-3β / CCL19

2001 • 146 citations

Failure of neutrophil chemotactic function in septic patients*

2002 • 130 citations

CXCR1 and CXCR2 Are Rapidly Down-Modulated by Bacterial Endotoxin Through a Unique Agonist-Independent, Tyrosine Kinase-Dependent Mechanism

1998 • 106 citations

Replication and Clearance of Respiratory Syncytial Virus

2002 • 99 citations

Effect of granulocyte-macrophage colony-stimulating factor and interleukin-3 on interleukin-8 production by human neutrophils and monocytes

1993 • 94 citations

Chronic neutropenia associated with autoimmune disease

2002 • 92 citations

Toll-like receptor-4 is involved in eliciting an LPS-induced oxidative burst in neutrophils

2003 • 91 citations

Mycobacterium tuberculosis 19-kDa Lipoprotein Promotes Neutrophil Activation

2001 • 88 citations

Human neutrophils release the Leu-8 lymph node homing receptor during cell activation

1990 • 80 citations

Alterations of neutrophil responses to tumor necrosis factor alpha and interleukin-8 following human endotoxemia

1994 • 46 citations

Regulation of GRO alpha production in human granulocytes.

1995 • 46 citations

Neutrophil survival is prolonged in the airways of healthy infants and infants with RSV bronchiolitis

2002 • 43 citations

Inhibition of Leukocyte Emigration Induced During the Systemic Inflammatory Reaction In Vivo Is Not Due to IL-8

1998 • 16 citations