Apoptotic cell clearance in systemic lupus erythematosus: I. Opsonization by antiphospholipid antibodies

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1995 • 2,877 citations

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

1994 • 1,722 citations

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

1990 • 1,618 citations

ANTICARDIOLIPIN ANTIBODIES: DETECTION BY RADIOIMMUNOASSAY AND ASSOCIATION WITH THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

1983 • 1,413 citations

Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

1990 • 1,294 citations

Antiphospholipid Antibodies: Anticardiolipin and the Lupus Anticoagulant in Systemic Lupus Erythematosus (SLE) and in Non-SLE Disorders

1990 • 1,093 citations

Phagocyte recognition of cells undergoing apoptosis

1993 • 1,000 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus.

1993 • 637 citations

Antibody to Cardiolipin as a Predictor of Fetal Distress or Death in Pregnant Patients with Systemic Lupus Erythematosus

1985 • 594 citations

Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus.

1994 • 555 citations

Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

1994 • 535 citations

Immunology and Clinical Importance of Antiphospholipid Antibodies

1991 • 490 citations

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.

1996 • 485 citations

The Second International Anti-Cardiolipin Standardization Workshop/The Kingston Anti-Phospholipid Antibody Study (KAPS) Group

1990 • 420 citations

Phosphatidylserine Externalization during CD95-induced Apoptosis of Cells and Cytoplasts Requires ICE/CED-3 Protease Activity

1996 • 386 citations

Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies [see comments]

1994 • 364 citations

"Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding.

1995 • 337 citations

Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: A model for autoimmune fetal loss

1990 • 320 citations

Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies [see comments]

1994 • 317 citations

BIOLOGICALLY FALSE POSITIVE SEROLOGIC TESTS FOR SYPHILIS

1952 • 315 citations

Immunology of the antiphospholipid antibody syndrome

1996 • 311 citations

Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells.

1991 • 278 citations

Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis.

1996 • 270 citations

A Phospholipid-β2-Glycoprotein I Complex Is an Antigen for Anticardiolipin Antibodies Occurring in Autoimmune Disease But Not with Infection

1992 • 262 citations

Novel packages of viral and self-antigens are generated during apoptosis.

1995 • 249 citations

Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner.

1996 • 210 citations

Nucleosome‐restricted antibodies are detected before anti‐dsdna and/or antihistone antibodies in serum of mrl‐mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria

1994 • 207 citations

Antiphospholipid antibody syndrome: Immunologic and clinical aspects

1990 • 199 citations

Fc receptors

1997 • 198 citations

The natural history of systemic lupus erythematosus: An approach to its study through chronic biologic false positive reactors

1955 • 197 citations

Association of antiphospholipid antibodies with central nervous system disease in systemic lupus erythematosus

1995 • 192 citations

Textbook of Rheumatology

1993 • 176 citations

Enhancement of macrophage phagocytosis upon iC3b deposition on apoptotic cells

1996 • 158 citations

Apoptotic cell clearance in systemic lupus erythematosus: II. Role of ?2-glycoprotein I

1998 • 146 citations

Anticardiolipin antibodies—clinical associations

1986 • 140 citations

The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolution.

1996 • 135 citations

Beta 2 glycoprotein I and placental anticoagulant protein I in placentae from patients with antiphospholipid syndrome.

1994 • 121 citations

Antiphospholipid antibodies and thrombosis. A consequence, coincidence, or cause?

1993 • 119 citations

THE LUPUS ANTICOAGULANT/ANTIPHOSPHOLIPID SYNDROME

1996 • 116 citations

Clinical consequences of antiphospholipid antibodies: an historic cohort study.

1994 • 115 citations

Presentation of self peptides by dendritic cells. Possible implications for the pathogenesis of rheumatoid arthritis

1996 • 97 citations

IgG anti-cardiolipin antibodies in murine lupus.

1989 • 88 citations

Daudi lymphoma killing triggers the programmed death of cytotoxic V gamma 9/V delta 2 T lymphocytes.

1995 • 61 citations

Recent Developments in the Understanding of Antinuclear Autoantibodies

1996 • 56 citations

Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms [editorial; comment]

1994 • 54 citations

Apoptosis and Autoimmunity

1995 • 49 citations

Still Immunodetectable Nuclear RNPs Are Extruded from the Cytoplasm of Spontaneously Apoptotic Thymocytes

1997 • 45 citations

Antiphospholipid Antibodies

1994 • 44 citations

Nuclear ribonucleoprotein-containing structures undergo severe rearrangement during spontaneous thymocyte apoptosis. A morphological study by electron microscopy

1997 • 42 citations

Lymphocyte apoptosis and apoptosis‐associated gene expression in Sjögren's syndrome

1996 • 40 citations

CD95 engagement releases calcium from intracellular stores of long term activated, apoptosis-prone gammadelta T cells.

1996 • 38 citations

A single-step staining procedure for the detection and sorting of unfixed apoptotic thymocytes.

1993 • 33 citations

Detection of apoptotic cells by annexin V labeling at electron microscopy.

1997 • 22 citations

Deleted Work

1955 • 0 citations