Gradient model describes the spatial-temporal expression pattern ofHOXA genes in the developing vertebrate limb

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Hox genes in vertebrate development

1994 • 2,057 citations

Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 • 719 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

A positive feedback loop coordinates growth and patterning in the vertebrate limb

1994 • 702 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

1993 • 660 citations

Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony

1994 • 631 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development

1996 • 588 citations

Analysis of Hox gene expression in the chick limb bud

1996 • 480 citations

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

1994 • 470 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

Dynamics of Skeletal Pattern Formation in Developing Chick Limb

1979 • 269 citations

Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds.

1995 • 205 citations

Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage

1995 • 176 citations

The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

1992 • 175 citations

The initiation of the limb bud: Growth factors, Hox genes, and retinoids

1995 • 170 citations

Ectodermal-mesodermal interactions in the growth of limb buds in the chick embryo: Constancy and temporal limits of the ectodermal induction

1972 • 163 citations

Vertebrate limb development

1995 • 154 citations

Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton

1996 • 154 citations

Direct and continuous assessment by cells of their position in a morphogen gradient

1995 • 150 citations

The Establishment of Murine Hox-1 Expression Domains during Patterning of the Limb

1993 • 143 citations

The long and short of hedgehog signaling

1995 • 134 citations

Activation of Fgf-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb

1996 • 130 citations

Time, place and positional value in the chick limb-bud

1975 • 106 citations

Embryonic induction

1993 • 86 citations

Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern

1994 • 78 citations

Retinoic acid application to chick wing buds leads to a dose-dependent reorganization of the apical ectodermal ridge that is mediated by the mesenchyme

1989 • 78 citations

FGF‐2 mRNA and its antisense message are expressed in a developmentally specific manner in the chick limb bud and mesonephros

1995 • 75 citations

The regeneration of positional information in the amphibian limb

1977 • 72 citations

Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern

1994 • 72 citations

Sticky fingers: Hox genes and cell adhesion in vertebrate limb development

1996 • 59 citations

Outgrowth and Pattern Formation during Limb Ontogeny and Regeneration

1975 • 53 citations

Effect of FGF on Gene Expression in Chick Limb Bud Cells in Vivo and in Vitro

1995 • 53 citations

Does vitamin A act on pattern formation via the epidermis or the mesoderm?

1984 • 36 citations

Regeneration of HoxD Expression Domains during Pattern Regulation in Chick Wing Buds

1994 • 32 citations