Radiation-induced chromosome breaks in ataxia-telangiectasia cells remain open

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Structure and function of telomeres

1991 • 3,524 citations

Mammalian Telomeres End in a Large Duplex Loop

1999 • 2,372 citations

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

1997 • 2,086 citations

The age of cancer

2000 • 949 citations

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

2001 • 525 citations

hMre11 and hRad50 Nuclear Foci Are Induced During the Normal Cellular Response to DNA Double-Strand Breaks †

1997 • 504 citations

In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts

1998 • 503 citations

ATM-dependent phosphorylation of nibrin in response to radiation exposure

2000 • 474 citations

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

2000 • 446 citations

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

1999 • 397 citations

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang

2000 • 323 citations

Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

1999 • 322 citations

On the Nature of a Defect in Cells from Individuals with Ataxia-Telangiectasia

1985 • 298 citations

Subnuclear shuttling of human telomerase induced by transformation and DNA damage

2002 • 253 citations

The Absence of the DNA-Dependent Protein Kinase Catalytic Subunit in Mice Results in Anaphase Bridges and in Increased Telomeric Fusions with Normal Telomere Length and G-Strand Overhang

2001 • 201 citations

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1995 • 167 citations

ATM function and telomere stability

2002 • 165 citations

Initial Chromosome Damage but Not DNA Damage Is Greater in Ataxia Telangiectasia Cells

1992 • 140 citations

Molecular characterization of a 130-kb terminal microdeletion at 22q in a child with mild mental retardation.

1997 • 136 citations

An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH)

1998 • 126 citations

Chromosome healing in mouse embryonic stem cells

1999 • 101 citations

Radiosensitivity of Ataxia Telangiectasia and Nijmegen Breakage Syndrome Homozygotes and Heterozygotes as Determined by Three-Color FISH Chromosome Painting

2002 • 76 citations

Classifying by colors: FISH-based genome analysis

2001 • 63 citations

High frequency of spontaneous translocations revealed by FISH in cells from patients with the cancer-prone syndromes ataxia telangiectasia and Nijmegen breakage syndrome

2001 • 63 citations

Analysis of radiation-induced chromosomal aberrations using telomeric and centromeric PNA probes

2000 • 63 citations

Telomerase activity during the cell cycle and in gamma-irradiated hematopoietic cells

1997 • 57 citations

Telomeres, Telomerase and Chromosome Stability

1997 • 54 citations

Kinetics of Chromatid Aberrations in G2 Ataxia-telangiectasia Cells Exposed to X-rays and Ara A

1989 • 46 citations

Telomeres and radiation-induced chromosome breakage

1998 • 27 citations

Closing the gaps among a web of DNA repair disorders

2000 • 24 citations

Long but dysfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line

2001 • 14 citations

Regulation of telomerase activity by gamma-radiation in nasopharyngeal carcinoma cells.

2000 • 11 citations

Cytogenetic investigations in three cell types of a Saudi family with ataxia telangiectasia

1991 • 6 citations