Cellular responses of nucleus accumbens neurons to opiate-seeking behavior: i. sustained responding during heroin self-administration

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Drug Abuse: Hedonic Homeostatic Dysregulation

1997 • 2,472 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

1989 • 1,570 citations

Differential Effect of Stress on In Vivo Dopamine Release in Striatum, Nucleus Accumbens, and Medial Frontal Cortex

1989 • 1,107 citations

The patterns of afferent innervation of the core and shell in the “Accumbens” part of the rat ventral striatum: Immunohistochemical detection of retrogradely transported fluoro‐gold

1993 • 1,084 citations

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

1992 • 827 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

1984 • 644 citations

The Mesolimbic Dopamine System: From Motivation to Action

1992 • 591 citations

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

1982 • 560 citations

The Effects of Opioid Peptides on Dopamine Release in the Nucleus Accumbens: An In Vivo Microdialysis Study

1990 • 539 citations

Chapter 5 The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: evidence for a parallel organization

1991 • 506 citations

Destruction of dopaminergic nerve terminals in nucleus accumbens: Effect on d-amphetamine self-administration

1979 • 460 citations

Modulation of Cocaine Self-Administration in the Rat Through D-3 Dopamine Receptors

1993 • 452 citations

Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

1997 • 435 citations

Dopamine functions in appetitive and defensive behaviours

1992 • 396 citations

Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens

1988 • 358 citations

Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: Comparison with novelty and locomotion.

1992 • 350 citations

Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system

1983 • 309 citations

μ-Opioid receptor mRNA expression in the rat CNS: comparison to μ-receptor binding

1994 • 298 citations

Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: Comparison with novelty and locomotion.

1992 • 278 citations

Localization of drug reward mechanisms by intracranial injections

1992 • 274 citations

Examination of the neurochemical substrates mediating the motivational effects of opioids: role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors.

1993 • 274 citations

Role of primate basal ganglia and frontal cortex in the internal generation of movements

1992 • 261 citations

Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

1992 • 257 citations

Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors

1996 • 213 citations

Presynaptic dopamine D1 receptors attenuate excitatory and inhibitory limbic inputs to the shell region of the rat nucleus accumbens studied in vitro

1992 • 189 citations

Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats

1994 • 186 citations

A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats

1994 • 184 citations

Dopamine Depresses Excitatory and Inhibitory Synaptic Transmission by Distinct Mechanisms in the Nucleus Accumbens

1997 • 183 citations

Cortical afferents of the nucleus accumbens in the cat, studied with anterograde and retrograde transport techniques

1982 • 178 citations

Eating and drinking cause increased dopamine release in the nucleus accumbens and ventral tegmental area in the rat: Measurement by in vivo microdialysis

1992 • 178 citations

Drug- and behavior-associated changes in dopamine-related electrochemical signals during intravenous cocaine self-administration in rats

1994 • 173 citations

Tonic D2-mediated attenuation of cortical excitation in nucleus accumbens neurons recorded in vitro

1994 • 168 citations

Role of primate basal ganglia and frontal cortex in the internal generation of movements

1992 • 167 citations

Scheduled eating increases dopamine release in the nucleus accumbens of food-deprived rats as assessed with on-line brain dialysis

1988 • 166 citations

Phasic Firing of Single Neurons in the Rat Nucleus Accumbens Correlated with the Timing of Intravenous Cocaine Self-Administration

1996 • 151 citations

Comparison of Mesocorticolimbic Neuronal Responses During Cocaine and Heroin Self-Administration in Freely Moving Rats

1998 • 149 citations

Neuropharmacological evidence to suggest that the nucleus accumbens and subpallidal region contribute to exploratory locomotion

1984 • 140 citations

mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons.

1997 • 136 citations

Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats.

1993 • 122 citations

μ-Opioid Receptors Modulate NMDA Receptor-Mediated Responses in Nucleus Accumbens Neurons

1997 • 117 citations

Drug‐ and behavior‐associated changes in dopamine‐related electrochemical signals during intravenous heroin self‐administration in rats

1993 • 113 citations

Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation.

1996 • 110 citations

Enhancement of dopamine actions on rat nucleus accumbens neurones in vitro after methamphetamine pre‐treatment.

1989 • 108 citations

Behavioral associations of neuronal activity in the ventral tegmental area of the rat

1994 • 103 citations

Differential membrane properties and dopamine effects in the shell and core of the rat nucleus accumbens studied in vitro

1992 • 93 citations

Long lasting changes in morphine‐induced mesolimbic dopamine release after chronic morphine exposure

1993 • 92 citations

Cloning, Characterization, and Distribution of a μ-Opioid Receptor in Rat Brain

1994 • 90 citations

Lack of evidence for an involvement of nucleus accumbens dopamine D1 receptors in the initiation of heroin self-administration in the rat

1994 • 83 citations

Neuronal responses in prefrontal cortex and nucleus accumbens during heroin self-administration in freely moving rats

1997 • 80 citations

Opiate influences on nucleus accumbens neuronal electrophysiology: dopamine and non-dopamine mechanisms

1989 • 78 citations

Opioid peptides reduce synaptic transmission in the nucleus accumbens

1992 • 69 citations

Chronic flupentixol treatment potentiates the reinforcing properties of systemic heroin administration

1989 • 52 citations

Ultrastructural localization of δ-opioid receptor and Met5-enkephalin immunoreactivity in rat insular cortex

1995 • 48 citations

Suppression of exploratory locomotor activity by the local application of dopamine or l-noradrenaline to the nucleus accumbens of the rat

1983 • 40 citations

Electrophysiological responses of nucleus accumbens neurons to novelty stimuli and exploratory behavior in the awake, unrestrained rat

1998 • 37 citations

Changes in morphine self-administration after tel-diencephalic lesions in rats

1978 • 36 citations

Potentiation of haloperidol-induced catalepsy by ascorbic acid in rats and nonhuman primates

1986 • 26 citations

Ethanol Inhibits Single‐Unit Responses in the Nucleus Accumbens Evoked by Stimulation of the Basolateral Nucleus of the Amygdala

1997 • 14 citations