The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor that is common to other neutrophil antibiotics.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Genomic sequencing.

1984 • 8,343 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.

1992 • 530 citations

The CTAB-DNA precipitation method: a common mini-scale preparation of template DNA from phagemids, phages or plasmids suitable for sequencing.

1989 • 414 citations

Neutrophils and Host Defense

1988 • 375 citations

Antibiotic peptides as mediators of innate immunity

1992 • 345 citations

Amino acid sequence of PR‐39

1991 • 343 citations

Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils

1989 • 295 citations

The growth arrest-specific gene, gas1, is involved in growth suppression

1992 • 274 citations

Cloning of the cDNA of a Human Neutrophil Bactericidal Protein

1989 • 203 citations

Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils.

1990 • 194 citations

Antimicrobial polypeptides of human neutrophils

1990 • 188 citations

Elastinolytic activity of human cathepsin L

1986 • 185 citations

Strategies for the biosynthesis of bioactive peptides

1983 • 174 citations

Antibiotic proteins of human neutrophils.

1990 • 159 citations

Antimicrobial polypeptides of human neutrophils

1990 • 152 citations

Primary structure of a new cysteine proteinase inhibitor from pig leucocytes

1989 • 152 citations

Bombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis.

1991 • 146 citations

Isolation and characterization of human defensin cDNA clones.

1988 • 145 citations

Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules.

1990 • 145 citations

Acidic precursor revealed in human eosinophil granule major basic protein cDNA.

1988 • 133 citations

Complementary DNA sequence of rabbit CAP18—A unique lipopolysaccharide binding protein

1991 • 126 citations

The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes.

1989 • 116 citations

Chemical Synthesis and Enzymic Processing of Precursor Forms of Cecropins A and B

1989 • 109 citations

Stimulus-induced maturation of probactenecins, precursors of neutrophil antimicrobial polypeptides.

1991 • 95 citations

The structure of the rabbit macrophage defensin genes and their organ-specific expression.

1989 • 92 citations

On the fidelity of mRNA translation in the nuclease-treated rabbit reticulocyte lysate system

1989 • 83 citations

CDNA cloning of the neutrophil bactericidal peptide indolicidin

1992 • 74 citations

Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases

1991 • 52 citations

A New Type of Low-Molecular Mass Cysteine Proteinase Inhibitor from Pig Leukocytes

1989 • 39 citations

Antibiotics from within: antibacterials from human and animal sources

1990 • 29 citations

Neutrophil and Eosinophil Granules as Stores of “Defense” Proteins

1991 • 27 citations

A λ vector for directional cDNA cloning andin vitrotranscription

1987 • 14 citations