The role of poly(ADP-ribosyl)ation in the adaptive response

Adaptive Response of Human Lymphocytes to Low Concentrations of Radioactive Thymidine

1984 • 817 citations

Poly(ADP-ribose) polymerase: a molecular nick-sensor

1994 • 790 citations

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

1995 • 600 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

ADP-ribosylation of proteins. Enzymology and biological significance.

1987 • 374 citations

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

1990 • 271 citations

Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiation

1987 • 235 citations

The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.

1990 • 231 citations

Evidence that the [³H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism

1986 • 224 citations

Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents

1989 • 218 citations

A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage.

1995 • 200 citations

A Shuttle Mechanism for DNA‐Protein Interactions

1982 • 184 citations

Histone shuttling by poly ADP-ribosylation

1994 • 173 citations

Dual Function for Poly(ADP-ribose) Synthesis in Response to DNA Strand Breakage

1994 • 168 citations

Purification and characterization of poly(ADP-ribose) glycohydrolase. Different modes of action on large and small poly(ADP-ribose).

1986 • 155 citations

Histone shuttling by poly(ADP-ribosylation).

1992 • 152 citations

Is Radiation All Bad? The Search for Adaptation

1992 • 142 citations

Poly ADP-ribosylation: a histone shuttle mechanism in DNA excision repair

1992 • 135 citations

Noncovalent interactions of poly(adenosine diphosphate ribose) with histones

1992 • 126 citations

Chromosomal Aberrations: Basic and Applied Aspects

2011 • 118 citations

Poly(ADP-ribose)polymerase: a novel finger protein

1989 • 116 citations

Poly(ADP-ribose) molecules formed during DNA repair in vivo

1994 • 90 citations

Chromosomal Adaptive Response in Human Lymphocytes

1994 • 86 citations

Endoglycosidic cleavage of branched polymers by poly(ADP‐ribose) glycohydrolase

1994 • 76 citations

Targeting of histone tails by poly(ADP-ribose).

1993 • 70 citations

The carboxyl-terminal domain of human poly(ADP-ribose) polymerase. Overproduction in Escherichia coli, large scale purification, and characterization

1993 • 64 citations

Poly ADP-Ribosylation of Proteins

1989 • 56 citations

Mode of Action of Rat Liver Phosphodiesterase on a Polymer of Phosphoribosyl Adenosine Monophosphate and Related Compounds

1968 • 54 citations

ADP‐ribosylation of nucleolar proteins in HeLa tumor cells

1993 • 50 citations

Regulation of poly(ADP-ribose) polymerase. Histone-specific adaptations of reaction products

1991 • 39 citations

Evidence for Induced Radioresistance from Survival and Other End Points: An Introduction

1994 • 35 citations

Adaptation of Human Lymphocytes to Radiation or Chemical Mutagens: Differences in Cytogenetic Repair

1990 • 31 citations

Interactions of poly(ADP-ribose) with nuclear proteins

1995 • 29 citations

Response of human keratinocytes to extremely low concentrations of N-methyl-N′-nitro-N-nitrosoguanidine

1996 • 28 citations

A specific, low K_m ADP‐ribose pyrophosphatase from rat liver

1989 • 28 citations

Nicotinamide deficiency in human lymphocytes prevents the [3H]thymidine-induced adaptive response for the repair of X-ray-induced chromosomal damage

1987 • 27 citations

Evidence for a novel metabolic pathway of (ADP-ribose)N: Pyrophosphorolysis of ADP-ribose in HeLa S3 cell nuclei

1989 • 25 citations

Poly(ADP-ribose) accessibility to poly(ADP-ribose) glycohydrolase activity on poly(ADP-ribosyl)ated nucleosomal proteins

1986 • 23 citations

Biochemical changes associated with the adaptive response of human keratinocytes to N-methyl-N′-nitro-N-nitrosoguanidine

1996 • 8 citations