Further evidence for the genetic origin of mutations in mammalian somatic cells: The effects of ploidy level and selection stringency on dose-dependent chemical mutagenesis to purine analogue resistance in Chinese hamster ovary cells
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References (33)
Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants
1964 • 2,108 citations
On the nature of hereditable variation in cultured somatic cells
1976 • 497 citations
Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.
1968 • 460 citations
Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.
1968 • 376 citations
8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE
1972 • 273 citations
Chapter 7: Isolation of Mutants of Cultured Mammalian Cells
1973 • 232 citations
The dose-response relationship for ethyl methanesulfonate-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells
1975 • 193 citations
Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection
1974 • 174 citations
Mutation rates in cells at different ploidy levels
1971 • 171 citations
Somatic cell mutation detection and quantification of X-ray-induced mutation in cultured, diploid human fibroblasts
1973 • 169 citations
Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells
1973 • 158 citations
[9] Quantitative colonial growth of isolated mammalian cells
1962 • 156 citations
The effect of ploidy on chemical mutagenesis in cultured chinese hamster cells
1973 • 139 citations
GENETICS OF SOMATIC MAMMALIAN CELLS, X. COMPLEMENTATION ANALYSIS OF GLYCINE-REQUIRING MUTANTS
1969 • 135 citations
Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells
1974 • 133 citations
Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase
1974 • 128 citations
Mutagenesis of cultured mammalian cells by X-irradiation and ultraviolet light
1970 • 110 citations
Analogues of Nucleic Acid Components
1970 • 104 citations
Effect of Ploidy and Mutagens on Bromodeoxyuridine Resistance in Haploid and Diploid Frog Cells
1972 • 94 citations
The dose-response relationship for ultraviolet-light-induced mutations at the hypoxanthine-guanine phosphoribosyltransferase locus in Chinese hamster ovary cells
1975 • 87 citations
The role of metabolic cooperation in selection of hypoxanthine-guanine-phosphoribosyl-transferase (HG-PRT)-deficient mutants from diploid mammalian cell strains
1972 • 82 citations
Expression time and spontaneous mutability in the estimation of induced mutation frequency following treatment of chinese hamster cells by ultraviolet light
1972 • 77 citations
The mammalian cell as a microorganism
1960 • 68 citations
REQUIREMENT FOR CELL DISPERSION PRIOR TO SELECTION OF INDUCED AZAGUANINE-RESISTANT COLONIES OF CHINESE HAMSTER CELLS
1975 • 68 citations
Chromosome-Wide Event Accompanies the Expression of Recessive Mutations in Tetraploid Cells
1975 • 64 citations
Mutagenicity of hycanthone in mammalian cells
1972 • 61 citations
INDUCTION AND ANALYSIS OF GENE MUTATIONS IN CULTURED MAMMALIAN SOMATIC CELLS
1974 • 46 citations
PUROMYCIN RESISTANCE IN HAPLOID AND HETEROPLOID FROG CELLS: GENE OR MEMBRANE DETERMINED?
1971 • 38 citations
GENETICS OF SOMATIC MAMMALIAN CELLS, VII. INDUCTION AND ISOLATION OF NUTRITIONAL MUTANTS IN CHINESE HAMSTER CELLS
1968 • 31 citations
The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT)
1974 • 30 citations
Selection for temperature‐sensitive mutants of diploid and tetraploid mammalian cells
1974 • 24 citations
Ploidy level and mutation to hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) deficiency in Chinese hamster cells
1975 • 24 citations
Purines
1970 • 1 citations
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