Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

Histocompatibility Testing

1971 • 1,937 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

A familial disorder of uric acid metabolism and central nervous system function

1964 • 1,448 citations

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

1967 • 1,210 citations

Spontaneous Mutation in Man

1975 • 346 citations

Metabolic co-operation between biochemically marked mammalian cells in tissue culture

1969 • 325 citations

Genetic Analysis with Human—Mouse Somatic Cell Hybrids

1969 • 273 citations

8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE

1972 • 273 citations

A mutational assay system using the thymidine kinase locus in mouse lymphoma cells

1972 • 266 citations

Hybridization of Somatic Cells

2015 • 258 citations

Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin

1963 • 247 citations

Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents

1969 • 245 citations

X-Linked Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency: Heterozygote Has Two Clonal Populations

1968 • 195 citations

Mutation rates in cells at different ploidy levels

1971 • 171 citations

Somatic cell mutation detection and quantification of X-ray-induced mutation in cultured, diploid human fibroblasts

1973 • 169 citations

The spontaneous azaguanine-resistant mutants of diploid human fibroblasts

1972 • 161 citations

Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells

1973 • 158 citations

MAMMALIAN CELL GENETICS I. SELECTION AND CHARACTERIZATION OF MUTATIONS AUXOTROPHIC FOR L-GLUTAMINE OR RESISTANT TO 8-AZAGUANINE IN CHINESE HAMSTER CELLS IN VITRO

1969 • 145 citations

Chemical Mutagenesis at the Phosphoribosyltransferase Locus in Cultured Human Lymphoblasts

1972 • 140 citations

The effect of ploidy on chemical mutagenesis in cultured chinese hamster cells

1973 • 139 citations

A third phosphoǵlucomutase locus in man

1968 • 139 citations

Mutations Affecting the Structure of Hypoxanthine: Guanine Phosphoribosyltransferase in Cultured Chinese Hamster Cells

1973 • 139 citations

Human Hypoxanthine-Guanine Phosphoribosyltransferase

1971 • 125 citations

Purine Overproduction in Man Associated with Increased Phosphoribosylpyrophosphate Synthetase Activity

1973 • 118 citations

LYON HYPOTHESIS AND X-LINKED DISEASE

1967 • 114 citations

Mutagenesis of cultured mammalian cells by X-irradiation and ultraviolet light

1970 • 110 citations

Isolation and characterization of thymidine transport mutants of Chinese hamster cells

1969 • 108 citations

Formation of anucleate and multinucleate cells in normal and SV transformed WI-38 by cytochalasin B

1972 • 107 citations

Single-allele expression at an X-linked hyperuricemia locus in heterozygous human cells.

1968 • 105 citations

Diploid Azaguanine-Resistant Mutants of Cultured Human Fibroblasts

1970 • 102 citations

Mammalian cell genetics III. Characterization of x-ray-induced forward mutations in chinese hamster cell cultures

1971 • 101 citations

Effect of Ploidy and Mutagens on Bromodeoxyuridine Resistance in Haploid and Diploid Frog Cells

1972 • 94 citations

Communication between normal and enzyme deficient cells in tissue culture

1972 • 93 citations

Purification of IMP:Pyrophosphate Phosphoribosyltransferases, Catalytically Incompetent Enzymes in Lesch-Nyhan Disease

1971 • 93 citations

The role of metabolic cooperation in selection of hypoxanthine-guanine-phosphoribosyl-transferase (HG-PRT)-deficient mutants from diploid mammalian cell strains

1972 • 82 citations

Isolation and Characterization of HL-A Variants in Cultured Human Lymphoid Cells

1973 • 77 citations

Characterization of a Feedback-Resistant Phosphoribosylpyrophosphate Synthetase from Cultured, Mutagenized Hepatoma Cells That Overproduce Purines

1973 • 70 citations

Purine excretion by mammalian cells deficient in adenosine kinase

1973 • 70 citations

Evidence for linkage of 3-phosphoglycerate kinase, hypoxanthine-guanine-phosphoribosyl transferase, and glucose 6-phosphate dehydrogenase loci in Chinese hamster cells studied by using a relationship between gene multiplicity and enzyme activity

1972 • 63 citations

Nitrosoguanidine mutagenesis in synchronized hamster cells

1971 • 62 citations

Mutagenicity of hycanthone in mammalian cells

1972 • 61 citations

Reappearance of murine hypoxanthine guanine phosphoribosyl transferase activity in mouse A9 cells after attempted hybridisation with human cell lines

1972 • 60 citations

Chemical mutagenesis in mammals and man

1971 • 59 citations

DIAMINOPURINE-RESISTANT MUTANTS OF CULTURED, DIPLOID HUMAN FIBROBLASTS

1973 • 46 citations

Fate of Mitochondrial DNA in Human-Mouse Somatic Cell Hybrids

1972 • 45 citations

Reexpression of the Rat Hypoxanthine Phosphoribosyltransferase Gene in Rat-Human Hybrids

1973 • 45 citations

Restoration of Hypoxanthine Phosphoribosyl Transferase Activity in Mouse 1R Cells After Fusion with Chick-Embryo Fibroblasts

1973 • 44 citations

Origin of thymidine kinase deficient (TK−) haploid frog cells via an intermediate thymidine transport deficient (TT−) phenotype

1973 • 42 citations

Hypoxanthine-Guanine Phosphoribosyltransferase Variant Associated with Accelerated Purine Synthesis

1973 • 41 citations

Azaguanine-resistance as a manifestation of a new form of metabolic overproduction of uric acid

1972 • 39 citations

Inheritance of purine phosphoribosyltransferases in man.

1969 • 37 citations

Mutagenesis in cultured mammalian cells I. Spontaneous gene mutations in human and Chinese hamster cells

1972 • 35 citations

Cells with Phosphoribosyl Transferase Activity recovered from Mouse Cells resistant to 8-Azaguanine

1973 • 33 citations

THE LOCUS FOR HUMAN ADENINE PHOSPHORIBOSYLTRANSFERASE ON CHROMOSOME NO. 16

1974 • 28 citations

Dynamics of Human Spermatogenesis

1970 • 26 citations

Spontaneous and X-ray-induced genotypic and phenotypic resistance to 5-iodo-2′-deoxyuridine in lymphoma cells in vitro

1971 • 24 citations

The Parameters of Male Fertility

1973 • 23 citations

Microscale isoelectric focusing studies of mouse and human hypoxanthine-guanine phosphoribosyl transferases

1973 • 15 citations

Cytogenetics of spontaneous abortion

1970 • 12 citations

Mutation studies with human fibroblasts.

1973 • 6 citations

Maths and Music

1971 • 3 citations