Ploidy level and mutation to hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) deficiency in Chinese hamster cells

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

1967 • 1,210 citations

Deletion of thymidine kinase activity from L cells resistant to bromodeoxyuridine

1963 • 611 citations

A specific enzyme defect in gout associated with overproduction of uric acid.

1967 • 477 citations

Ouabain-resistant mutants of mouse and hamster cells in culture

1974 • 393 citations

Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.

1968 • 376 citations

Mutation rates in cells at different ploidy levels

1971 • 171 citations

Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells

1973 • 158 citations

MAMMALIAN CELL GENETICS I. SELECTION AND CHARACTERIZATION OF MUTATIONS AUXOTROPHIC FOR L-GLUTAMINE OR RESISTANT TO 8-AZAGUANINE IN CHINESE HAMSTER CELLS IN VITRO

1969 • 145 citations

The effect of ploidy on chemical mutagenesis in cultured chinese hamster cells

1973 • 139 citations

Isolation and characterization of thymidine transport mutants of Chinese hamster cells

1969 • 108 citations

Effect of Ploidy and Mutagens on Bromodeoxyuridine Resistance in Haploid and Diploid Frog Cells

1972 • 94 citations

Temperature-resistant variants in clonal populations of pig kidney cells

1967 • 75 citations

Reappearance of murine hypoxanthine guanine phosphoribosyl transferase activity in mouse A9 cells after attempted hybridisation with human cell lines

1972 • 60 citations

Mutation to 8-azaguanine resistance induced by γ-radiation in a chinese hamster cell line

1971 • 60 citations

GENETIC ANALYSIS OF AZAGUANINE RESISTANCE IN AN ESTABLISHED MOUSE CELL LINE

1970 • 56 citations

Genetics of human cell lines

1959 • 52 citations

Intracellular mosaicism (nuclear-/mitochondrial+) for thymidine kinase in mouse l cells

1972 • 47 citations

DIAMINOPURINE-RESISTANT MUTANTS OF CULTURED, DIPLOID HUMAN FIBROBLASTS

1973 • 46 citations

Restoration of Hypoxanthine Phosphoribosyl Transferase Activity in Mouse 1R Cells After Fusion with Chick-Embryo Fibroblasts

1973 • 44 citations

Origin of thymidine kinase deficient (TK−) haploid frog cells via an intermediate thymidine transport deficient (TT−) phenotype

1973 • 42 citations

Cells with Phosphoribosyl Transferase Activity recovered from Mouse Cells resistant to 8-Azaguanine

1973 • 33 citations

The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT)

1974 • 30 citations

Phenotypic Expression of Drug Resistance in Cell Cultures<xref ref-type="fn" rid="FN2">2</xref>

1967 • 28 citations

Evidence for linkage between glucose 6-phosphate dehydrogenase and hypoxanthine-guanine-phosphoribosyl transferase loci in Chinese hamster cells

1971 • 17 citations

Induction of hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT)-deficient mutants in diploid and tetraploid Chinese hamster cell lines

1973 • 2 citations