Phenotypic and functional properties of murine thymocytes. I. Precursors of cytolytic T lymphocytes and interleukin 2-producing cells are all contained within a subpopulation of "mature" thymocytes as analyzed by monoclonal antibodies and flow microfluorometry

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

T‐Cell Growth Factor

1980 • 917 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity.

1975 • 758 citations

Antibody production by hybridomas

1980 • 646 citations

Current concepts of the immunological function of the thymus.

1967 • 577 citations

Separation of mouse thymocytes into two subpopulations by the use of peanut agglutinin

1976 • 513 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies.

1981 • 386 citations

T-T-cell interactions during the vitro cytotoxic allograft responses. I. Soluble products from activated Lyl+ T cells trigger autonomously antigen-primed Ly23+ T cells to cell proliferation and cytolytic activity.

1978 • 330 citations

Characteristics of the immunocompetent cells in the mouse thymus: Cell population changes during cortisone-induced atrophy and subsequent regeneration

1970 • 247 citations

SYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE

1972 • 240 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

Generation of cytolytic T lymphocytes in vitro. IX. induction of secondary CTL responses in primary long-term MLC by supernatants from secondary MLC.

1978 • 166 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. I. Comparison of precursor frequencies for proliferative and cytolytic responses.

1979 • 132 citations

Thymus cell maturation

1975 • 127 citations

A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors.

1977 • 122 citations

An Lyt differentiated thymocyte subpopulation detected by flow microfluorometry

1979 • 122 citations

Localization of mouse isoantigens on the cell surface as revealed by immunofluorescence.

1967 • 116 citations

Subpopulations of T-lymphocytes. Physical separation, functional specialisation and differentiation pathways of sub-sets of thymocytes and thymus-dependent peripheral lymphocytes.

1975 • 116 citations

Cell-mediated immune response in vitro

1972 • 108 citations

T-cell lines which cooperate in generation of specific cytolytic activity

1979 • 105 citations

In vitro maturation of immature thymocytes into immunocompetent T cells in the absence of direct thymic influence

1978 • 92 citations

T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens.

1980 • 90 citations

Allograft immunity in the mouse. II. Physical studies of the development of cytotoxic effector cells from their immediate progenitors.

1973 • 80 citations

Differential binding of fluorescein-labeled lectins to mouse thymocytes: subsets revealed by flow microfluorometry.

1980 • 58 citations

Selective turnover and shedding of H-2K and H-2D antigens is controlled by the major histocompatibility complex. Implications for H-2-restricted recognition.

1980 • 57 citations

Peanut agglutinin. II. Characterization of the Thy‐1, Tla and Ig phenotype of peanut agglutinin‐positive cells in adult, embryonic and nude mice using double immunofluorescence

1979 • 54 citations

Intrathymic differentiation of cytotoxic T lymphocyte (CTL) precursors. I. The CTL immunocompetence of peanut agglutinin-positive (cortical) and negative (medullary) Lyt 123 thymocytes.

1980 • 50 citations

Distinct effects of T cell growth factors and thymic epithelial factors on the generation of cytotoxic T lymphocytes by thymocyte subpopulations.

1980 • 49 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. II. Effect of cortisone and cyclophosphamide on cytolytic T lymphocyte precursor frequencies in the thymus.

1979 • 48 citations

Characterization of a Monoclonal Anti-H-2Kb Antibody

2015 • 46 citations

Lymphocyte Subpopulations in the Thymus

1975 • 44 citations

Subpopulations of T‐Lymphocytes

1975 • 42 citations

Current Concepts of the Immunological Function of the Thymus

1967 • 36 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigens.

1981 • 31 citations

The use of a clonal assay for cytotoxic T lymphocytes to determine the Ly phenotypes of the cytotoxic precursor and effector cells to alloantigens and trinitrophenyl-modified self antigens.

1980 • 23 citations

Serological detection of H-2K- and H-2D-gene products

1980 • 14 citations

Cytotoxic and fluorescent assays for thymocyte subpopulations differing in surface thy-1 level

1979 • 12 citations

Association of Ly phenotypes, T cell function and MHC recognition.

1980 • 11 citations

The generation of cytolytic activity in mixed leukocyte cultures: cortisone-resistant thymocytes are deficient in helper T lymphocytes.

1981 • 5 citations