The Obese Strain of Chickens: An Animal Model with Spontaneous Autoimmune Thyroiditis
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References (209)
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1981 • 75 citations
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Obese strain (OS) chickens with spontaneous autoimmune thyroiditis have a deficiency in thymic nurse cells.
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1982 • 59 citations
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1973 • 58 citations
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1970 • 58 citations
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1970 • 57 citations
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1986 • 57 citations
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1982 • 56 citations
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1982 • 48 citations
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1962 • 47 citations
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1972 • 46 citations
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1986 • 46 citations
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1981 • 44 citations
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1979 • 43 citations
Enhanced response to Con A and production of TCGF by lymphocytes of obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
1985 • 42 citations
Increased Iodine Uptake by Obese Strain Thyroid Glands Transplanted to Normal Chick Embryos
1976 • 41 citations
Spontaneous Thyroiditis in the Obese Strain of Chickens
1970 • 38 citations
Effects of antiserum containing thyroglobulin antibody on the chicken thyroid gland
1978 • 36 citations
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1982 • 36 citations
Genetic Background of Spontaneous Autoimmune Thyroiditis in the Obese Strain of Chickens Studied in Hybrids with an Inbred Line
1986 • 36 citations
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1978 • 35 citations
Increased 131I uptake by the thyroid glands of Obese strain (OS) chickens derived from non-Protamone-supplemented hens.
1974 • 35 citations
Requirement of T cells for the development of spontaneous autoimmune thyroiditis in obese strain (OS) chickens.
1981 • 34 citations
Genetic influences on spontaneous autoimmune thyroiditis in (CS x OS)F2 chickens
1981 • 34 citations
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1973 • 33 citations
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1988 • 32 citations
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1979 • 32 citations
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1969 • 31 citations
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1969 • 30 citations
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1981 • 29 citations
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1976 • 29 citations
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1986 • 28 citations
Effect of testosterone treatments for varying periods on autoimmune development and on specific infiltrating leukocyte populations in the thyroid gland of obese strain chickens
1986 • 28 citations
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1985 • 27 citations
Thymic nurse cells: a school for alloreactive and autoreactive cortical thymocytes?
1986 • 27 citations
Influence of major histocompatibility haplotype on autoimmune disease varies in different inbred families of chickens.
1979 • 27 citations
Distribution and functional analysis of B-L/Ia-positive cells in the chicken: Expression of B-L/Ia antigens on thyroid epithelial cells in spontaneous autoimmune thyroiditis
1984 • 26 citations
In vitro T cell hyperreactivity in Obese strain (OS) chickens is due to a defect in nonspecific suppressor mechanism(s).
1985 • 26 citations
Hypothesis: immunogenetic analysis of spontaneous autoimmune thyroiditis in obese strain (OS) chickens: A two-gene family model
1988 • 25 citations
Genetic control of immune response to the dinitrophenol group inbred lines of chickens.
1974 • 25 citations
?Natural? chicken antibodies to red blood cells are mainly directed against the B-G antigen, and their occurrence is independent of spontaneous autoimmune thyroiditis
1984 • 24 citations
The pathogenesis of murine systemic lupus erythematosus. Rous--Whipple Award lecture.
1979 • 24 citations
Spontaneous and methylcholanthrene-enhanced thyroiditis in BUF rats. I. The incidence and severity of the disease, and the genetics of susceptibility.
1975 • 24 citations
The decreased growth rate of obese strain chicken thyroid cells provides in vitro evidence for a primary target organ abnormality in chickens susceptible to autoimmune thyroiditis
1983 • 23 citations
Studies on thyroid proteins
1967 • 23 citations
Abnormal response to minor histocompatibility antigens in Obese strain chickens.
1976 • 23 citations
Thyroid Disease with Monoclonal (Immunoglobulin G λ) Antibody to Triiodothyronine and Thyroxine*
1983 • 22 citations
Is autoimmunity a side-effect of interleukin 2 production?
1986 • 22 citations
The role of testosterone in spontaneous autoimmune thyroiditis of Obese strain (OS) chickens
1988 • 21 citations
Analysis of triiodothyronine and thyroxine-binding autoantibodies in chickens susceptible to autoimmune thyroiditis.
1985 • 20 citations
Spontaneous thyroiditis in the obese strain of chickens. VI. Thyroxine-binding antibodies.
1971 • 20 citations
Genetic control of the response of chicken T lymphocytes to concanavalin A: cellular localization of the low responder defect
1983 • 19 citations
Proportional increase of bursa-derived cells in chickens of the Obese strain
1974 • 19 citations
Suppression of Spontaneous Autoimmune Thyroiditis in Obese Strain (OS) Chickens with Anti-Bursa and Anti-Thymus Sera
1971 • 19 citations
Immunofluorescent studies of thyroid auto-antibodies in chickens of the obese strain (OS).
1970 • 19 citations
Development of an enzyme-linked immunosorbent assay for the detection of autoantibodies against thyroglobulin in chickens
1984 • 18 citations
Spontaneous and Methylcholanthrene-Enhanced Thyroiditis in Buf Rats
1975 • 18 citations
Preliminary studies on food and water consumption of prediafoetic chinese hamsters
1970 • 18 citations
Virological Investigations of Chickens with Spontaneous Autoimmune Thyroiditis II. Examination of Tissues by Electron Microscopy
1970 • 17 citations
Lymphoid thyroiditis following immunization with group A streptococcal vaccine.
1978 • 17 citations
Interactions and quantitative analysis of immunoregulatory cells in the chicken thymus.
1985 • 16 citations
Analyses of the serum concentrations and antigenic determinants of thyroglobulin in chickens susceptible to autoimmune thyroiditis.
1983 • 16 citations
Nonthyroid autoantibodies in Obese strain (OS) chickens
1984 • 16 citations
Immunofluorescence studies on the codistribution immune deposits and complement in the thyroid glands of obese strain (OS) chickens
1983 • 16 citations
Thyroglobulin-Binding Lymphoid Cells in Obese Strain (OS) Chickens
1975 • 15 citations
Localization of IgGFc and Complement Receptors in Chicken Lymphoid Tissue
1981 • 15 citations
Spontaneous thyroiditis in the obese strain of chickens. V. The effect of sublethal total body X-irradiation on the development of the disease.
1970 • 15 citations
Autoimmunity : genetic, immunologic, virologic, and clinical aspects
1977 • 15 citations
GENETIC ANALYSIS OF EXTRATHYROIDAL FEATURES OF OBESE STRAIN (OS) CHICKENS WITH SPONTANEOUS AUTOIMMUNE THYROIDITIS
1988 • 14 citations
Parabiosis between obese (OS) and normal strain chicken embryos. Examination of skin grafts, lymphocyte chimerism and autoimmune thyroiditis.
1973 • 14 citations
Local production of immunoglobulin in the thyroid gland of obese strain (OS) chickens.
1974 • 14 citations
Sex steroid and glucocorticoid receptors in the bursa of fabricius of obese strain chickens spontaneously developing autoimmune thyroiditis
1986 • 14 citations
Bursectomy and Thymectomy of Obese Strain (OS) Chickens with Spontaneous Autoimmune Thyroiditis and Simultaneous Experimental Allergic Encephalomyelitis
1972 • 14 citations
Mechanisms of T cell hyperreactivity in obese strain (OS) chickens with spontaneous autoimmune thyroiditis: lack in nonspecific suppression is due to a primary adherent cell defect.
1987 • 14 citations
SERUM LIPID PATTERN IN CHICKENS OF THE OBESE STRAIN
1972 • 13 citations
Cyclosporin A enhances Streptozocin-induced diabetes in CD-1 mice
1987 • 13 citations
Intrinsic thyroid hyperactivity in avian strains susceptible to autoimmune thyroiditis
1980 • 12 citations
Immunogenetic and ontogenetic studies of chickens with selective IgA deficiency and autoimmune thyroiditis
1977 • 12 citations
Diminished glucocorticoid tonus in obese strain (OS) chickens with spontaneous autoimmune thyroiditis: Increased plasma levels of a physicochemically unaltered corticosteroid-binding globulin but normal total corticosterone plasma concentration and normal glucocorticoid receptor contents in lymphoid tissues
1988 • 12 citations
T Cell Hyperreactivity in Obese Strain (OS) Chickens. Different Mechanisms Operative in Spleen and Peripheral Blood Lymphocyte Activation
1987 • 11 citations
Immune complexes in tissues of obese strain (OS) chickens.
1981 • 11 citations
Spontaneous Thyroiditis in the Obese Strain of Chickens
1971 • 11 citations
A three-layer immunoradiometric assay for antibodies in different immunoglobulin classes and its application to the detection of chicken thyroglobulin autoantibodies and of antibodies to sheep erythrocytes
1980 • 11 citations
Spontaneous Thyroiditis in the Obese Strain of Chickens
1970 • 11 citations
Characterization of chicken lymphocyte subsets separated by peanut agglutinin
1983 • 10 citations
Genetically-Controlled Severity of Autoimmune Thyroiditis in Obese Strain (OS) Chickens Is Expressed at Both the Humoral and Cellular Effector Mechanism Levels
1983 • 9 citations
Possible Role of Pancreatic Insulin and Glucagon in the Hyperlipidemia and Obesity of Obese Strain of Chicken
1986 • 8 citations
The nature of active and passive thyroglobulin binding lymphoid cells in Obese strain (OS) chickens
1975 • 8 citations
Spontaneous autoimmune thyroiditis in Praomys (Mastomys) natalensis
1982 • 7 citations
Accumulation of radioiodine in thyroids of chicks of the Obese strain with hereditary thyroiditis and of their parental strain
1973 • 7 citations
Demonstration and characterization of thyroglobulin-binding peripheral blood cells in Hashimoto patients by fluoroimmunocytoadherence
1978 • 6 citations
Killer cells in the chicken: A microcytotoxicity assay using antigen-coated erythrocytes as targets
1980 • 6 citations
Functional consequences of perceived interleukin deficiencies? Analysis employing NZB x C58 recombinant inbred mice.
1985 • 6 citations
Simultaneous Induction of Experimental Allergic Encephalomyelitis in Obese Strain (OS) Chickens with Spontaneous, Hereditary Autoimmune Thyroiditis
1972 • 5 citations
The induction of tolerance to thyroglobulin significantly reduces the severity of thyroiditis in obese strain chickens.
1985 • 5 citations
Fc Receptor-Bearing Lymphoid Cells in the Chicken II. Relative Increase of Fc(IgG) Receptor Bearing Cells in Obese Strain Chickens
1978 • 4 citations
Decreased Level of Thymidine in the Serum of Obese Strain (OS) Chickens with Spontaneous Autoimmune Thyroiditis
1988 • 4 citations
T cell hyperproliferation in autoimmunity prone obese strain (OS) chickens is independent of abnormal mitogen binding invitro and can be demonstrated invivo
1988 • 3 citations
Production in vitro of thyroglobulin autoantibody by obese strain (OS) chickens.
1987 • 2 citations
Some methodological aspects of the haemolytic plaque forming cell assay in the chicken system [proceedings].
1979 • 2 citations
Progress on Autoimmunity
2021 • 1 citations
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