Hypothesis: immunogenetic analysis of spontaneous autoimmune thyroiditis in obese strain (OS) chickens: A two-gene family model

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

1983 • 1,275 citations

ABERRANT EXPRESSION OF HLA-DR ANTIGEN ON THYROCYTES IN GRAVES' DISEASE: RELEVANCE FOR AUTOIMMUNITY

1983 • 710 citations

AUTO-ANTIBODIES IN HASHIMOTO'S DISEASE (LYMPHADENOID GOITRE)

1956 • 581 citations

Autoimmune Murine Thyroiditis Relation to Histocompatibility (H-2) Type

1971 • 410 citations

Studies on organ specificity. V. Changes in the thyroid glands of rabbits following active immunization with rabbit thyroid extracts.

1956 • 390 citations

BIRTH CONTROL FOR PROBLEM PARENTS

1964 • 381 citations

Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.

1980 • 331 citations

The traditional and a new version of the mouse H–2 complex

1981 • 325 citations

The Impact On The Developing Embryo And Newborn Animal Of Adult Homologous Cells

2007 • 282 citations

A three-locus model for the chicken major histocompatibility complex

1977 • 215 citations

Nomenclature for chicken major histocompatibility (B) complex

1982 • 191 citations

The Major Histocompatibility System in Man and Animals

1977 • 185 citations

Induction of Autoimmune Thyroiditis in Chickens by Dietary Iodine

1985 • 182 citations

THE IMPACT ON THE DEVELOPING EMBRYO AND NEWBORN ANIMAL OF ADULT HOMOLOGOUS CELLS

1957 • 180 citations

Induction of autoimmunity in good and poor responder mice with mouse thyroglobulin and lipopolysaccharide.

1977 • 177 citations

Studies on Organ Specificity

1956 • 159 citations

Regulation of Autoimmune Response to Mouse Thyroglobulin: Influence of H-2D-end Genes

1979 • 144 citations

Hashimoto's Thyroiditis Is Associated with HLA-DRw3

1978 • 140 citations

In situ immune complexes, lymphocyte subpopulations, and HLA-DR-positive epithelial cells in Hashimoto thyroiditis.

1985 • 124 citations

HEREDITARY HYPOTHYROIDISM IN THE DOMESTIC FOWL

1966 • 115 citations

The Obese strain (OS) of chickens: An animal model with spontaneous autoimmune thyroiditis

1974 • 105 citations

Familial studies of autoimmune thyroiditis.

1967 • 102 citations

Regulation of experimental autoimmune thyroiditis: Mapping of susceptibility to the I-A subregion of the mouse H-2

1982 • 97 citations

Hereditary Autoimmune Thyroiditis in the Fowl

1968 • 94 citations

The presence of thyroid autoantibodies in children and adolescents with autoimmune thyroid disease and in their siblings and parents

1982 • 94 citations

Evidence for an association between immune responsiveness of chicken to (T, G)-A–L and the major histocompatibility system

1974 • 92 citations

Animal models of comparative and developmental aspects of immunity and disease

1979 • 89 citations

STUDIES ON THE ORGAN SPECIFICITY

1941 • 88 citations

Relation between the Major Histocompatibility (B) Locus and Autoimmune Thyroiditis in Obese Chickens

1974 • 84 citations

Genetic control of immune responses in chickens

1975 • 79 citations

Spontaneous autoimmune thyroiditis - a bird's eye view

1985 • 77 citations

Effect of castration and sex hormones on experimental autoimmune thyroiditis

1981 • 75 citations

Obese strain (OS) chickens with spontaneous autoimmune thyroiditis have a deficiency in thymic nurse cells.

1984 • 61 citations

ADDITIONAL BLOOD GROUP SYSTEMS IN THE CHICKEN

1962 • 60 citations

Pathogenesis of spontaneous autoimmune thyroiditis in Obese strain (OS) chickens.

1982 • 59 citations

Elevation of corticosteroid-binding globulin in obese strain (OS) chickens: possible implications for the disturbed immunoregulation and the development of spontaneous autoimmune thyroiditis.

1986 • 57 citations

Post-partum thyroiditis and goitrous (hashimoto's) thyroiditis are associated with HLA-DR4

1985 • 52 citations

Analysis of lymphocytes infiltrating the thyroid gland of Obese strain chickens.

1985 • 51 citations

The Obese Strain (OS) of Chickens With Spontaneous Autoimmune Thyroiditis: Review of Recent Data

1981 • 49 citations

Genetic Control of Immune Responses in Chickens

1975 • 47 citations

Electron microscopic studies in chickens of the obese strain with spontaneous hereditary autoimmune thyroiditis.

1972 • 46 citations

The Role of Genetically‐Determined Primary Alterations of the Target Organ in the Development of Spontaneous Autoimmune Thyroiditis in Obese Strain (OS) Chickens

1986 • 46 citations

A reassessment of studies on the aggregation of thyroid autoimmunity in families of thyroiditis patients.

1967 • 44 citations

Abnormal Thyroid Regulation in Chickens with Autoimmune Thyroiditis*

1979 • 43 citations

Genetic Determinants of Thyroiditis in the OS Chicken

1976 • 42 citations

Enhanced response to Con A and production of TCGF by lymphocytes of obese strain (OS) chickens with spontaneous autoimmune thyroiditis.

1985 • 42 citations

Increased Iodine Uptake by Obese Strain Thyroid Glands Transplanted to Normal Chick Embryos

1976 • 41 citations

Components and Concepts of Antigenic Strength

1970 • 41 citations

The genetic lesions of autoimmunity.

1980 • 39 citations

Predisposition to organ-specific autoimmunity in Obese strain (OS) chickens: reactivity to thyroid, gastric, adrenal and pancreatic cytoplasmic antigens.

1982 • 36 citations

Effects of antiserum containing thyroglobulin antibody on the chicken thyroid gland

1978 • 36 citations

Genetic Background of Spontaneous Autoimmune Thyroiditis in the Obese Strain of Chickens Studied in Hybrids with an Inbred Line

1986 • 36 citations

Increased 131I uptake by the thyroid glands of Obese strain (OS) chickens derived from non-Protamone-supplemented hens.

1974 • 35 citations

Genetic influences on spontaneous autoimmune thyroiditis in (CS x OS)F2 chickens

1981 • 34 citations

The Major Histocompatibility System of the Chicken

1977 • 34 citations

REGULATION OF EXPERIMENTAL AUTOIMMUNE THYROIDITIS: INFLUENCE OF NON‐H‐2 GENES

1982 • 33 citations

IMMUNOGENETIC DETECTION OF B LOCUS GENOTYPES IN CHICKENS WITH AUTOIMMUNE THYROIDITIS

1973 • 33 citations

GENETIC FACTORS IN SPONTANEOUS AUTOIMMUNE THYROIDITIS IN OS CHICKENS

1979 • 32 citations

Studies of the effects of sex hormones on autosomal and x‐linked genetic control of induced and spontaneous antibody production

1979 • 28 citations

Spontaneous autoimmune thyroiditis in obese strain chickens: A genetic analysis of target organ abnormalities

1985 • 27 citations

Influence of major histocompatibility haplotype on autoimmune disease varies in different inbred families of chickens.

1979 • 27 citations

Thymic nurse cells: a school for alloreactive and autoreactive cortical thymocytes?

1986 • 27 citations

Distribution and functional analysis of B-L/Ia-positive cells in the chicken: Expression of B-L/Ia antigens on thyroid epithelial cells in spontaneous autoimmune thyroiditis

1984 • 26 citations

In vitro T cell hyperreactivity in Obese strain (OS) chickens is due to a defect in nonspecific suppressor mechanism(s).

1985 • 26 citations

Genetic factors controlling the susceptibility to experimental autoimmune thyroiditis in inbred rat strains.

1981 • 25 citations

Genetic control of immune response to the dinitrophenol group inbred lines of chickens.

1974 • 25 citations

The decreased growth rate of obese strain chicken thyroid cells provides in vitro evidence for a primary target organ abnormality in chickens susceptible to autoimmune thyroiditis

1983 • 23 citations

Abnormal response to minor histocompatibility antigens in Obese strain chickens.

1976 • 23 citations

Number of Mouse Histocompatibility Genes Involved in Skin Grafting from Strain BALB/cAn to Strain DBA/2

1958 • 23 citations

Spontaneous thyroiditis in laboratory rats

1969 • 22 citations

H-2K mutation controls immune response phenotype of autoimmune thyroiditis. Critical expression of mutant gene product in both thymus and thyroid glands.

1980 • 22 citations

Erythrocyte-specific anti-nuclear factors in chickens of the obese strain (OS).

1971 • 19 citations

Autoimmune Diseases

1981 • 17 citations

Nonthyroid autoantibodies in Obese strain (OS) chickens

1984 • 16 citations

Immunofluorescence studies on the codistribution immune deposits and complement in the thyroid glands of obese strain (OS) chickens

1983 • 16 citations

Protection against Autoimmune Thyroiditis in Guinea Pigs by Thyroglobulin Antiserum

1974 • 16 citations

Mechanisms of T cell hyperreactivity in obese strain (OS) chickens with spontaneous autoimmune thyroiditis: lack in nonspecific suppression is due to a primary adherent cell defect.

1987 • 14 citations

Parabiosis between obese (OS) and normal strain chicken embryos. Examination of skin grafts, lymphocyte chimerism and autoimmune thyroiditis.

1973 • 14 citations

[Spontaneous autoimmune thyroiditis in chickens].

1970 • 12 citations

Immune complexes in tissues of obese strain (OS) chickens.

1981 • 11 citations

Spontaneous Thyroiditis in the Obese Strain of Chickens

1971 • 11 citations

Genetic and Cellular Control of Spontaneous Autoimmune Thyroiditis in OS Chickens

1977 • 10 citations

Genetically-Controlled Severity of Autoimmune Thyroiditis in Obese Strain (OS) Chickens Is Expressed at Both the Humoral and Cellular Effector Mechanism Levels

1983 • 9 citations

Functional Analysis of B‐L (Ia‐Like) Antigen‐Bearing Chicken Peripheral Blood Cells

1984 • 7 citations

Tolerance to alloantigens of the A and B systems in chickens.

1978 • 6 citations

Comparison of experimental allergic thyroiditis and spontaneous hereditary autoimmune thyroiditis in chickens.

1971 • 5 citations

Materno-embryonally transferred antibodies precipitate autoimmune thyroiditis in obese strain (OS) chickens.

1986 • 5 citations