Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid
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References (40)
The biochemistry of apoptosis
2000 • 7,314 citations
Apoptosis in the Pathogenesis and Treatment of Disease
1995 • 6,610 citations
A simple, rapid, and sensitive DNA assay procedure
1980 • 5,006 citations
Caspases: the executioners of apoptosis
1997 • 4,674 citations
Data for biochemical research
1987 • 3,056 citations
Alpha-lipoic acid as a biological antioxidant
1995 • 1,920 citations
Triggering and modulation of apoptosis by oxidative stress
2000 • 1,315 citations
Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis
1997 • 663 citations
Structure and function of vacuolar class of ATP-driven proton pumps
1989 • 600 citations
[40] Preparation and characterization of chloramines
1986 • 345 citations
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate
2001 • 336 citations
Mechanisms of hypochlorite injury of target cells.
1990 • 261 citations
Myeloperoxidase
2000 • 261 citations
Lysosomal involvement in apoptosis
2001 • 222 citations
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid
1988 • 177 citations
Inhibition of myeloperoxidase by benzoic acid hydrazides
1995 • 171 citations
Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
1999 • 170 citations
Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase
1990 • 169 citations
Activation of the NF-κB transcription factor in a T-lymphocytic cell line by hypochlorous acid
1997 • 143 citations
Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation.
1998 • 139 citations
Human HL-60 myeloid leukemia cells transport dehydroascorbic acid via the glucose transporters and accumulate reduced ascorbic acid
1994 • 124 citations
Redox Signaling and the Control of Cell Growth and Death
1996 • 120 citations
Scavenging of hypochlorous acid by lipoic acid
1991 • 112 citations
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid
1997 • 104 citations
Efficacy of Hypochlorous Acid Scavengers in the Prevention of Protein Carbonyl Formation
1996 • 99 citations
Myeloperoxidase biosynthesis by a human promyelocytic leukemia cell line: insight into myeloperoxidase deficiency
1986 • 98 citations
Activation of Caspase 3 in HL-60 Cells Exposed to Hydrogen Peroxide
1999 • 95 citations
Hypochlorous Acid Stimulation of the Mitogen-Activated Protein Kinase Pathway Enhances Cell Survival
2001 • 94 citations
Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells
1999 • 93 citations
Myeloperoxidase Is Involved in H2O2-induced Apoptosis of HL-60 Human Leukemia Cells
2000 • 90 citations
Relative reactivities ofN-chloramines and hypochlorous acid with human plasma constituents
2001 • 75 citations
Inhibition by ascorbic acid of apoptosis induced by oxidative stress in HL-60 myeloid leukemia cells
1999 • 68 citations
-Lipoic acid and -lipoamide prevent oxidant-induced lysosomal rupture and apoptosis
2001 • 60 citations
Neutrophil Antioxidant Capacity During the Respiratory Burst: Loss of Glutathione Induced by Chloramines
1997 • 51 citations
Hypochlorous Acid Activates the Tumor Suppressor Protein p53 in Cultured Human Skin Fibroblasts
1998 • 46 citations
A spectrophotometric assay for chlorine-containing compounds
1991 • 42 citations
Monochloramine-Induced Cell Growth Inhibition and Apoptosis in a Rat Gastric Mucosal Cell Line
1997 • 36 citations
The Putative Benzene Metabolite 2,3,5-Tris(glutathion-S-yl)hydroquinone Depletes Glutathione, Stimulates Sphingomyelin Turnover, and Induces Apoptosis in HL-60 Cells
2000 • 35 citations
Myeloperoxidase is involved in H2O2-induced apo- ptosis of HL-60 human leukemia cells.
2001 • 19 citations
Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids
2001 • 13 citations