Hypochlorous Acid Stimulation of the Mitogen-Activated Protein Kinase Pathway Enhances Cell Survival

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

The causes and prevention of cancer.

1995 • 1,326 citations

Activation of Mitogen-activated Protein Kinase by H2O2

1996 • 1,202 citations

[18] Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides

1994 • 1,183 citations

Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide: Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

1998 • 933 citations

Neutrophils in Human Diseases

1987 • 852 citations

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

1998 • 742 citations

Interaction of reactive oxygen species with ion transport mechanisms

1998 • 659 citations

Myeloperoxidase: a key regulator of neutrophil oxidant production

1997 • 641 citations

Oxidative Stress-Induced Actin Reorganization Mediated by the p38 Mitogen-Activated Protein Kinase/Heat Shock Protein 27 Pathway in Vascular Endothelial Cells

1997 • 569 citations

Free radicals and phagocytic cells

1995 • 487 citations

Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of oxidant to hypochlorite

1985 • 459 citations

Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes

1996 • 351 citations

Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease.

1996 • 349 citations

Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species

1996 • 332 citations

Mitogen-Activated Protein Kinase Cascades as Regulators of Stress Responses

1998 • 331 citations

Kinetics and Mechanisms of Hypochlorous Acid Reactions

1995 • 330 citations

Myeloperoxidase

1999 • 294 citations

The Inactivation Mechanism of Low Molecular Weight Phosphotyrosine-protein Phosphatase by H2O2

1998 • 217 citations

Fyn and JAK2 Mediate Ras Activation by Reactive Oxygen Species

1999 • 206 citations

Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytes

1998 • 182 citations

Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells

1999 • 93 citations

Oxidative stress induces tyrosine phosphorylation of PDGF α-and β-receptors and pp60c−src in mesangial cells

1996 • 84 citations

Peroxynitrite Modulates the Activation of p38 and Extracellular Regulated Kinases in PC12 Cells

2000 • 78 citations

Epidermal growth factor receptor is modulated by redox through multiple mechanisms

2000 • 76 citations

Activation of Protein Phosphorylation by Oxidants in Vascular Endothelial Cells: Identification of Tyrosine Phosphorylation of Caveolin

1997 • 71 citations

Differential Regulation of Extracellular Signal-Regulated Kinase and Nuclear Factor-κB Signal Transduction Pathways by Hydrogen Peroxide and Tumor Necrosis Factor

1998 • 56 citations

Hypochlorous Acid Disrupts the Adhesive Properties of Subendothelial Matrix

1997 • 56 citations

Initiation of Rapid, P53-Dependent Growth Arrest in Cultured Human Skin Fibroblasts by Reactive Chlorine Species

2000 • 53 citations

Impairment of cardiac contractility and sarcoplasmic reticulum Ca²⁺ ATPase activity by hypochlorous acid: reversal by dithiothreitol

1991 • 51 citations

Active oxygen species mediate the solar ultraviolet radiation‐dependent increase in the tumour suppressor protein p53 in human skin fibroblasts

1997 • 49 citations

Hypochlorous Acid Activates the Tumor Suppressor Protein p53 in Cultured Human Skin Fibroblasts

1998 • 46 citations

Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells

1999 • 34 citations

Inhibition of hypochlorous acid-mediated reactions by desferrioxamine. Implications for the mechanism of cellular injury by neutrophils

1990 • 28 citations

Cited By (0)

Loading...