Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

1979 • 1,356 citations

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1984 • 1,092 citations

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1984 • 1,007 citations

Dopaminergic Neurotoxicity of 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine in Mice

1984 • 1,005 citations

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 • 913 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

The Metabolism of Rat Brain Mitochondria

1970 • 560 citations

Neurotoxicity of the meperidine analogue N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on brain catecholamine neurons in the mouse

1984 • 194 citations

AN APPRAISAL OF THE USE OF MONOAMINE OXIDASE AS AN ENZYME MARKER FOR THE OUTER MEMBRANE OF RAT LIVER MITOCHONDRIA

1970 • 141 citations

Differential inhibition of mitochondrial respiratory control by N-1-substituted, 3-, 4-substituted pyridinium halides

1984 • 2 citations