Direct High Affinity Modulation of Connexin Channel Activity by Cyclic Nucleotides

The Gap Junction Communication Channel

1996 • 1,896 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

1996 • 1,247 citations

CONNEXINS, CONNEXONS, AND INTERCELLULAR COMMUNICATION

1996 • 1,180 citations

Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

1992 • 1,031 citations

Junctional intercellular communication and the control of growth

1979 • 965 citations

Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside

1981 • 678 citations

Structural Basis for Phosphotyrosine Peptide Recognition by Protein Tyrosine Phosphatase 1B

1995 • 575 citations

Transmission of hormonal stimulation by cell-to-cell communication

1978 • 490 citations

Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo

1984 • 434 citations

Decrease of gap junction permeability induced by dopamine and cyclic adenosine 3':5'-monophosphate in horizontal cells of turtle retina

1984 • 429 citations

Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA.

1989 • 427 citations

Equilibrium properties of a voltage-dependent junctional conductance.

1981 • 391 citations

cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.

1986 • 374 citations

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

1996 • 346 citations

The charybdotoxin family of K+ channel-blocking peptides

1995 • 341 citations

Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes.

1989 • 341 citations

Isoform Composition of Connexin Channels Determines Selectivity among Second Messengers and Uncharged Molecules

1998 • 307 citations

Anatomy of a Conformational Change: Hinged "Lid" Motion of the Triosephosphate Isomerase Loop

1990 • 282 citations

Kinetic properties of a voltage-dependent junctional conductance.

1981 • 265 citations

Permeability of junctions between animal cells

1977 • 226 citations

An Integrated view of the Molecular Toxinology of Sodium Channel Gating in Excitable Cells

1987 • 221 citations

Cyclic nucleotide-binding domains in proteins having diverse functions.

1992 • 201 citations

Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions.

1988 • 199 citations

Voltage Dependence of Junctional Conductance in Early Amphibian Embryos

1979 • 186 citations

Cyclic nucleotide phosphodiesterases: Structure, regulation and drug action

1991 • 176 citations

Ligand- and voltage-gated ion channels

1995 • 171 citations

The effect of membrane cholesterol content on ion transport processes in plasma membranes

1997 • 166 citations

Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels

1992 • 164 citations

Cell-free synthesis and assembly of connexins into functional gap junction membrane channels

1997 • 161 citations

Role of Phosphate and Other Proton-Donating Anions in Respiration-Coupled Transport of Ca ²⁺ by Mitochondria

1974 • 158 citations

The role of gap junction membrane channels in development

1996 • 158 citations

Inotropic effect of cyclic AMP in calf ventricular muscle studied by a cut end method.

1976 • 155 citations

Membrane topology and quaternary structure of cardiac gap junction ion channels

1992 • 150 citations

Binding of cAMP derivatives to Dictyostelium discoideum cells. Activation mechanism of the cell surface cAMP receptor.

1983 • 135 citations

Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites

1989 • 124 citations

Biogenesis of Polytopic Membrane Proteins: Membrane Segments Assemble within Translocation Channels prior to Membrane Integration

1996 • 123 citations

A kinetic intermediate in the reaction of an antigenic peptide and I–Ek

1989 • 122 citations

OmpA protein of Escherichia coli outer membrane occurs in open and closed channel forms.

1994 • 120 citations

Cyclic nucleotide phosphodiesterases : structure, regulation and drug action

1990 • 112 citations

Interaction of deoxycholate and of detergents with the coat protein of bacteriophage f1

1975 • 107 citations

Arginine-glycine-aspartic acid binding leading to molecular stabilization between integrin alpha v beta 3 and its ligand.

1991 • 107 citations

Regulation of Connexin Channels by pH

1999 • 104 citations

Cardiac gap junctions: three distinct single channel conductances and their modulation by phosphorylating treatments

1992 • 100 citations

Mixing of connexins in gap junction membrane channels.

1995 • 99 citations

Molecular mechanisms of epithelial cell junctions : from development to disease

1994 • 99 citations

An Essential Aspartic Acid at Each of Two Allosteric cGMP-binding Sites of a cGMP-specific Phosphodiesterase

1995 • 96 citations

Hormone-induced intercellular signal transfer dissociates cyclic AMP-dependent protein kinase.

1984 • 95 citations

The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium.

1992 • 94 citations

Gap junction regulation in the uterus and ovaries of immature rats by estrogen and progesterone

1995 • 93 citations

Effect of Nucleotide on the Binding of Peptides to 70-kDa Heat Shock Protein

1995 • 90 citations

Membrane integration of in vitro-translated gap junctional proteins: co- and post-translational mechanisms.

1996 • 76 citations

Handbook of membrane channels : molecular and cellular physiology

1994 • 76 citations

Lipid-Protein Interactions

2019 • 75 citations

Localization of gap junction proteins, connexins 32 and 26, in rat and guinea pig liver as revealed by quick-freeze, deep-etch immunoelectron microscopy.

1993 • 58 citations

Nicotinic acetylcholine receptor channels are influenced by the physical state of their membrane environment

1996 • 55 citations

Crystallographic binding studies with triosephosphate isomerases: Conformational changes induced by substrate and substrate‐analogues

1992 • 49 citations

Accessibility and Environment Probing Using Cysteine Residues Introduced along the Putative Transmembrane Domain of the Major Coat Protein of Bacteriophage M13

1996 • 49 citations

Structural Effects of Neutral and Anionic Lipids on the Nicotinic Acetylcholine Receptor

1996 • 49 citations

Transduction of the chemotactic cAMP signal across the plasma membrane ofDictyostelium cells

1995 • 47 citations

Complex formation between clathrin and uncoating ATPase.

1994 • 45 citations

Channel-Forming Activity of Immunoaffinity-Purified Connexin32 in Single Phospholipid Membranes

1996 • 45 citations

Local Dynamics of the M13 Major Coat Protein in Different Membrane-Mimicking Systems

1996 • 39 citations

Voltage-dependent gap junction channels are formed by connexin32, the major gap junction protein of rat liver

1991 • 39 citations

Ion channels in single bilayers induced by rat connexin32

1992 • 37 citations

Biomembrane Electrochemistry

1994 • 37 citations

Force enhancement without changes in cross-bridge turnover kinetics: the effect of EMD 57033

1997 • 37 citations

The isolation of a dimer of gene 8 protein of bacteriophage fd

1976 • 35 citations

Random chimeragenesis of G-protein-coupled receptors. Mapping the affinity of the cAMP chemoattractant receptors in Dictyostelium.

1994 • 33 citations

Random Mutagenesis of the cAMP Chemoattractant Receptor, c/AR1, of Dictyostelium

1997 • 32 citations

Transport-Specific isolation of large channels reconstituted into lipid vesicles

1989 • 18 citations

In Situ Aggregational State of M13 Bacteriophage Major Coat Protein in Sodium Cholate and Lipid Bilayers

1997 • 17 citations

pH-Metric Study of Reaction Centers from Photosynthetic Bacteria in Micellular Solutions: Protonatable Groups Equilibrate with the Aqueous Bulk Phase

1997 • 16 citations