Arginine-glycine-aspartic acid binding leading to molecular stabilization between integrin alpha v beta 3 and its ligand.

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 1,031 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 841 citations

A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells

1986 • 634 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties

1981 • 557 citations

Novel purification of vitronectin from human plasma by heparin affinity chromatography.

1988 • 525 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response.

1989 • 416 citations

The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis.

1982 • 399 citations

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

1980 • 373 citations

Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function

1988 • 372 citations

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface.

1991 • 357 citations

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

1990 • 328 citations

Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

1984 • 314 citations

Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]

1988 • 311 citations

Integrins and tumor cell dissemination.

1989 • 294 citations

The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin.

1990 • 282 citations

[27] Arginine-glycine-aspartic acid adhesion receptors

1987 • 263 citations

Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells.

1988 • 256 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

Purification and functional characterization of integrin alpha v beta 5. An adhesion receptor for vitronectin.

1990 • 238 citations

Cell surface distribution of fibronectin and vitronectin receptors depends on substrate composition and extracellular matrix accumulation.

1988 • 228 citations

Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor.

1990 • 193 citations

Adhesion Plaques: Sites of Transmembrane Interaction Between the Extracellular Matrix and the Actin Cytoskeleton

1987 • 145 citations

Association of fibronectin and vinculin with focal contacts and stress fibers in stationary hamster fibroblasts.

1982 • 138 citations

Fibronectin-degrading proteases from the membranes of transformed cells

1987 • 134 citations

Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa.

1987 • 133 citations

Molecular requirements for the adhesion and spreading of hamster fibroblasts

1979 • 125 citations

An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion.

1991 • 103 citations

Fibronectin in adhesion, spreading and cytoskeletal organization of cultured fibroblasts

1982 • 85 citations

Studies on cell adhesion and recognition. II. The kinetics of cell adhesion and cell spreading on surfaces coated with carbohydrate-reactive proteins (glycosidases and lectins) and fibronectin.

1981 • 83 citations

Association of fibrin with the platelet cytoskeleton.

1984 • 64 citations

Kinetic and morphological evidence for endocytosis of mammalian cell integrin receptors by using an anti-fibronectin receptor β subunit monoclonal antibody

1989 • 54 citations

Examination of irreversible platelet-fibrinogen interactions

1985 • 49 citations

Studies on the mechanism of cell attachment to a substratum with serum in the medium: Further evidence supporting a requirement for two biochemically distinct processes

1974 • 29 citations

The coordinate organization of vinculin and of actin filaments during the early stages of fibroblast spreading on a substratum.

1985 • 14 citations