Detection of TAP Family Dimerizations by anin VivoAssay in Mammalian Cells

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Erythropoietin Receptor Activation by a Ligand-Induced Conformation Change

1999 • 624 citations

A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

1997 • 528 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

The major substrates for TAP in vivo are derived from newly synthesized proteins

2000 • 408 citations

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

1992 • 407 citations

Presentation of viral antigen controlled by a gene in the major histocompatibility complex

1990 • 381 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

DNA sequence of the white locus of Drosophila melanogaster

1984 • 282 citations

Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex

1991 • 262 citations

Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays

1999 • 228 citations

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes.

1988 • 224 citations

Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells

1994 • 201 citations

The ABCs of Immunology: Structure and Function of TAP, the Transporter Associated with Antigen Processing

2004 • 179 citations

Cloning and characterization of the scarlet gene of Drosophila melanogaster.

1989 • 126 citations

Characterization of ABCB9, an ATP Binding Cassette Protein Associated with Lysosomes

2000 • 107 citations

A heterodimeric coiled-coil peptide pair selected in vivo from a designed library- versus -library ensemble 1 1Edited by A. R. Fersht

2000 • 105 citations

Visualization of biochemical networks in living cells

2001 • 102 citations

Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing.

1994 • 89 citations

Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing.

1996 • 75 citations

Herpes Simplex Virus Inhibitor ICP47 Destabilizes the Transporter Associated with Antigen Processing (TAP) Heterodimer

1998 • 65 citations

Sequence of a cDNA from theDrosophila melanogaster whitegene

1990 • 63 citations

Direct demonstration of genetic alterations at the dihydrofolate reductase locus after gamma irradiation.

1982 • 44 citations

Three-dimensional Structure of Transporter Associated with Antigen Processing (TAP) Obtained by Single Particle Image Analysis

2001 • 41 citations

Novel Peptide-Binding Proteins and Peptide Transport in Normal and TAP-Deficient Microsomes

1997 • 39 citations

Intracellular Location, Complex Formation, and Function of the Transporter Associated with Antigen Processing in Yeast

1997 • 37 citations

Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits

2002 • 37 citations

A Half-Type ABC Transporter TAPL Is Highly Conserved between Rodent and Man, and the Human Gene Is Not Responsive to Interferon- in Contrast to TAP1 and TAP2

2000 • 25 citations

A defect in the presentation of intracellular viral antigens is restored by interferon‐γ in cell lines with impaired major histocompatibility complex class I assembly

1992 • 19 citations