Agouti-Related Protein (AGRP) Has a Central Inhibitory Action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis; Comparisons between the Effect of AGRP and Neuropeptide Y on Energy Homeostasis and the HPT Axis

Central nervous system control of food intake

2000 • 6,305 citations

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

1997 • 2,992 citations

Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases

2002 • 1,665 citations

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

1998 • 1,136 citations

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

2000 • 795 citations

Proopiomelanocortin Neurons Are Direct Targets for Leptin in the Hypothalamus

1997 • 731 citations

Integration of NPY, AGRP, and Melanocortin Signals in the Hypothalamic Paraventricular Nucleus

1999 • 603 citations

A C-Terminal Fragment of Agouti-Related Protein Increases Feeding and Antagonizes the Effect of Alpha-Melanocyte Stimulating Hormonein Vivo

1998 • 555 citations

What’s in a Name? In Search of Leptin’s Physiologic Role¹

1998 • 527 citations

Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin

1998 • 518 citations

Leptin Prevents Fasting-Induced Suppression of Prothyrotropin-Releasing Hormone Messenger Ribonucleic Acid in Neurons of the Hypothalamic Paraventricular Nucleus*

1997 • 488 citations

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

2001 • 442 citations

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

2001 • 426 citations

Adrenergic activation of triiodothyronine production in brown adipose tissue

1983 • 395 citations

AgRP(83–132) Acts as an Inverse Agonist on the Human-Melanocortin-4 Receptor

2001 • 375 citations

Hypothalamic Agouti-Related Protein Messenger Ribonucleic Acid Is Inhibited by Leptin and Stimulated by Fasting*

1999 • 374 citations

Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling

2001 • 333 citations

α-Melanocyte-Stimulating Hormone Is Contained in Nerve Terminals Innervating Thyrotropin-Releasing Hormone-Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Prevents Fasting-Induced Suppression of Prothyrotropin-Releasing Hormone Gene Expression

2000 • 304 citations

Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism

1994 • 303 citations

Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat

1987 • 285 citations

Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats

1991 • 274 citations

Decreased Receptor Binding of Biologically Inactive Thyrotropin in Central Hypothyroidism

1985 • 259 citations

The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin

2000 • 257 citations

Thyroid hormone–sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform–specific

2001 • 256 citations

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

1996 • 249 citations

Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor

2001 • 248 citations

What's in a Name? In Search of Leptin's Physiologic Role

1998 • 240 citations

Reversal of Cancer Anorexia by Blockade of Central Melanocortin Receptors in Rats

2001 • 216 citations

Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.

1985 • 206 citations

Leptin Receptor Long-form Splice-variant Protein Expression in Neuron Cell Bodies of the Brain and Co-localization with Neuropeptide Y mRNA in the Arcuate Nucleus

1999 • 204 citations

Regulation of the uncoupling protein gene expression

1997 • 203 citations

AgRP(83-132) Acts as an Inverse Agonist on the Human-Melanocortin-4 Receptor

2001 • 197 citations

Neuropeptide-Y and ACTH-immunoreactive innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamus of the rat

1988 • 181 citations

Neuropeptide Y Has a Central Inhibitory Action on the Hypothalamic-Pituitary-Thyroid Axis*

2001 • 161 citations

Effects of Chronic Central Nervous System Administration of Agouti-Related Protein in Pair-Fed Animals

2001 • 152 citations

Direct Evidence for a Role of the “Spot 14” Protein in the Regulation of Lipid Synthesis

1995 • 148 citations

Arcuate Nucleus Ablation Prevents Fasting-Induced Suppression of ProTRH mRNA in the Hypothalamic Paraventricular Nucleus

1998 • 138 citations

Intracerebroventricular administration of α-melanocyte stimulating hormone increases phosphorylation of CREB in TRH- and CRH-producing neurons of the hypothalamic paraventricular nucleus

2002 • 133 citations

Triiodothyronine Exerts Direct Cell-Specific Regulation of Thyrotropin-Releasing Hormone Gene Expression in the Hypothalamic Paraventricular Nucleus*

1988 • 125 citations

Agouti-Related Protein Containing Nerve Terminals Innervate Thyrotropin-Releasing Hormone Neurons in the Hypothalamic Paraventricular Nucleus*

1999 • 120 citations

Fasting and Leptin Modulate Adipose and Muscle Uncoupling Protein: Divergent Effects Between Messenger Ribonucleic Acid and Protein Expression¹

1999 • 108 citations

Thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine.

1992 • 108 citations

Effect of Starvation and Subsequent Refeeding on Thyroid Function and Release of Hypothalamic Thyrotropin-Releasing Hormone

1992 • 102 citations

Hypophysiotropic Thyrotropin-Releasing Hormone-Synthesizing Neurons in the Human Hypothalamus Are Innervated by Neuropeptide Y, Agouti-Related Protein, and α-Melanocyte-Stimulating Hormone¹

2000 • 101 citations

Endocrine function of neuropeptide Y knockout mice

1997 • 101 citations

The Human Type 2 Iodothyronine Deiodinase Is a Selenoprotein Highly Expressed in a Mesothelioma Cell Line

2001 • 97 citations

Interrelationships among thyroxine, growth hormone, and the sympathetic nervous system in the regulation of 5'-iodothyronine deiodinase in rat brown adipose tissue.

1986 • 80 citations

Evidence of UCP1-independent regulation of norepinephrine-induced thermogenesis in brown fat

2000 • 54 citations

The Thyrotropin-Releasing Hormone Gene 1998: Cloning, Characterization, and Transcriptional Regulation in the Central Nervous System, Heart, and Testis

1998 • 52 citations

Total and Free Serum Thyroid Hormone Concentrations in Fetal and Adult Pregnant and Nonpregnant Guinea Pigs^*

1986 • 45 citations

The influence of dexamethasone on serum thyrotrophin and thyrotrophin synthesis in the rat

1989 • 34 citations

Corticotropin‐releasing hormone‐synthesizing neurons of the human hypothalamus receive neuropeptide Y‐immunoreactive innervation from neurons residing primarily outside the infundibular nucleus

2002 • 30 citations

Metabolic adaptations in brown adipose tissue of the hamster in extreme ambient temperatures

1976 • 15 citations