Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

A TH1→TH2 switch is a critical step in the etiology of HIV infection

1993 • 1,403 citations

Lymphokine Production by Human T Cells in Disease States

1994 • 1,351 citations

The cytokine handbook

1994 • 1,121 citations

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

The role of IL-10 in crossregulation of TH1 and TH2 responses

1991 • 775 citations

The Th1–Th2 hypothesis of HIV infection: new insights

1994 • 708 citations

Biological properties of interleukin 10

1992 • 656 citations

Fibrogenic cytokines: the role of immune mediators in the development of scar tissue

1991 • 607 citations

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.

1994 • 541 citations

The Pathology of Hepatitis C

1992 • 539 citations

Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

1991 • 406 citations

Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.

1995 • 344 citations

Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction.

1991 • 267 citations

An evaluation of competitor type and size for use in the determination of mRNA by competitive PCR.

1995 • 126 citations

Intrahepatic hepatitis C RNA levels do not correlate with degree of liver injury in patients with chronic hepatitis C

1996 • 125 citations

Increased intrahepatic messenger RNA expression of interleukins 2, 6, and 8 in human cirrhosis

1994 • 94 citations

Pathogenetic mechanisms of hepatocellular damage in chronic hepatitis C virus infection

1994 • 80 citations

Immunologic responsiveness in American cutaneous leishmaniasis lesions.

1990 • 76 citations

Tolerance to rat liver allografts. I. Differences between tolerance and rejection are more marked in the B cell compared with the T cell or cytokine response.

1994 • 72 citations

Intragraft cytokine mRNA levels in human liver allograft rejection analysed by reverse transcription and semiquantitative polymerase chain reaction amplification

1993 • 60 citations

Expression of cytokine-dependent immune adhesion molecules by hepatocytes and bile duct cells in chronic hepatitis C

1994 • 59 citations

Immunological Aspects of HCV Infection

1994 • 54 citations

Serum levels of soluble immune factors and pathogenesis of chronic hepatitis C, and their relation to therapeutic response to interferon-α

1994 • 46 citations

Genes for Interleukin-1, Interleukin-6, and Tumor Necrosis Factor are Expressed at Markedly Reduced Levels in the Livers of Patients with Severe Liver Disease

1991 • 28 citations

Interferon-γ, interleukin (IL)-2 and IL-2 receptor expressions in hepatitis C virus-infected liver

1993 • 21 citations

Increased soluble IL-2 receptor levels in HCV-infected haemophiliacs: a possible indicator of liver disease severity

1994 • 11 citations

Levels of cytokine expression in rat liver allograft rejection compared to allograft tolerance.

1992 • 4 citations