Deletion analysis of the mouse m1 muscarinic acetylcholine receptor: effects on phosphoinositide metabolism and down-regulation

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 • 766 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

1988 • 691 citations

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

1987 • 687 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

Molecular Properties of the Muscarinic Acetylcholine Receptor

1987 • 478 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence

1986 • 344 citations

Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core

1987 • 318 citations

The yeast α-factor receptor: structural properties deduced from the sequence of theSTE2gene

1985 • 318 citations

Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization

1985 • 284 citations

A single amino acid substitution in rhodopsin (lysine 248—-leucine) prevents activation of transducin.

1988 • 260 citations

Mutations that uncouple the beta-adrenergic receptor from Gs and increase agonist affinity.

1987 • 259 citations

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

1989 • 259 citations

The avian beta-adrenergic receptor: primary structure and membrane topology.

1986 • 252 citations

Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells

1988 • 216 citations

Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.

1986 • 194 citations

Location of a region of the muscarinic acetylcholine receptor involved in selective effector coupling

1988 • 167 citations

Molecular distinction between muscarinic acetylcholine receptor subtypes

1987 • 162 citations

Isolation, sequence, and functional expression of the mouse M1 muscarinic acetylcholine receptor gene.

1988 • 126 citations

Muscarinic acetylcholine receptor regulation by accelerated rate of receptor loss

1979 • 111 citations

The biphasic response of muscarinic cholinergic receptors in cultured heart cells to agonists. Effects on receptor number and affinity in intact cells and homogenates.

1982 • 108 citations

In vivo regulation of muscarinic acetylcholine receptor number and function in embryonic chick heart.

1981 • 103 citations

Regulation of muscarinic cholinergic receptor density in neuroblastoma cells by brief exposure to agonist: possible involvement in desensitization of receptor function.

1985 • 75 citations

Cloned M1 muscarinic receptors mediate both adenylate cyclase inhibition and phosphoinositide turnover.

1988 • 72 citations

Binding of Agonists and Antagonists to Muscarinic Acetylcholine Receptors on Intact Cultured Heart Cells

1983 • 52 citations

A novel subtype of muscarinic receptor identified by homology screening

1987 • 49 citations

Electrophysiological characterization of cloned m1 muscarinic receptors expressed in A9 L cells.

1988 • 39 citations

Newer quaternary ammonium opioid antagonists

1986 • 32 citations

Muscarinic acetylcholine receptor function in chick heart cells cultured in serum-free medium

1988 • 29 citations