Lamotrigine-antiparkinsonian activity by blockade of glutamate release?

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Functional architecture of basal ganglia circuits: neural substrates of parallel processing

1990 • 4,029 citations

Primate models of movement disorders of basal ganglia origin

1990 • 3,722 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

Pharmacological Studies on Lamotrigine, A Novel Potential Antiepileptic Drug

1986 • 558 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1989 • 455 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Altered Tonic Activity of Neurons in the Globus Pallidus and Subthalamic Nucleus in the Primate MPTP Model of Parkinsonism

1987 • 420 citations

Excitatory amino acid binding sites in the basal ganglia of the rat: A quantitative autoradiographic study

1992 • 369 citations

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study

1991 • 303 citations

NMDA antagonists potentiate antiparkinsonian actions of <scp>L</scp>‐dopa in monoamine‐depleted rats

1990 • 285 citations

Lamotrigine, a new anticonvulsant: Pharmacokinetics in normal humans

1987 • 273 citations

PCP (Phencyclidine): Historical and Current Perspectives

1982 • 260 citations

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine‐depleted rats and MPTP‐treated monkeys

1991 • 258 citations

Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex

1989 • 251 citations

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 229 citations

Anatomy and Physiology of the Subthalamic Nucleus: A Driving Force of the Basal Ganglia

1987 • 206 citations

A simple model for studying benzodiazepines: Potentiation of hyperactivity induced by cocaine in mice

1982 • 193 citations

Acute Effects of Lamotrigine (BW430C) in Persons With Epilepsy

1986 • 191 citations

Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice

1989 • 174 citations

Parkinsonian Symptomatology An Anatomical and Physiological Analysisaa

1988 • 168 citations

Neurochemical and Behavioral Aspects of Lamotrigine

1991 • 142 citations

A novel NMDA antagonist, MK-801, impairs performance in a hippocampal-dependent spatial learning task

1989 • 141 citations

Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-Dopa in models of Parkinson's disease

1991 • 135 citations

Clinical Pharmacology of Lamotrigine

1991 • 126 citations

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

1987 • 117 citations

Human Safety of Lamotrigine

1991 • 105 citations

Pharmacological study of the cortical-induced excitation of subthalamic nucleus neurons in the rat: Evidence for amino acids as putative neurotransmitters

1987 • 94 citations

Lamotrigine protects against kainate but not ibotenate lesions in rat striatum

1990 • 77 citations

Central determinants of age-related declines in motor function.

1988 • 71 citations

Neural mechanisms in disorders of Movement

1989 • 59 citations

Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice

1991 • 41 citations

Chronic Phencyclidine (PCP) Abuse: A Psychiatric Perspective

1980 • 34 citations

Increase in glutamate sensitivity of subthalamic nucleus neurons following bilateral decortication: a microiontophoretic study in the rat

1987 • 11 citations