Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

The current status of the dopamine hypothesis of schizophrenia

1988 • 962 citations

Antipsychotic Drugs, Neurotransmitters, and Schizophrenia

1978 • 500 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 229 citations

A simple model for studying benzodiazepines: Potentiation of hyperactivity induced by cocaine in mice

1982 • 193 citations

Antipsychotic drugs, neurotransmitters, and schizophrenia

1978 • 64 citations

Locus coeruleus norepinephrine-containing neurons: effects produced by acute and subchronic treatment with antipsychotic drugs and amphetamine

1986 • 55 citations

Phencyclidine: behavioral and biochemical evidence supporting a role for dopamine.

1983 • 50 citations

Interactions of neuroleptic compounds at α2-adrenergic receptor affinity states in bovine caudate nucleus

1983 • 21 citations