Immunolocalization of intracellular interleukin‐4 in normal human peripheral blood basophils

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

1990 • 954 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Interleukin-4: a prototypic immunoregulatory lymphokine

1991 • 878 citations

Inflammatory Mediators in Late Antigen-Induced Rhinitis

1985 • 708 citations

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

1992 • 697 citations

Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.

1991 • 676 citations

Induction of human IgE synthesis in B cells by mast cells and basophils

1993 • 662 citations

Interleukin 4 is localized to and released by human mast cells.

1992 • 589 citations

Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation.

1993 • 391 citations

Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)/cachectin by mouse mast cells stimulated via the Fc epsilon RI. A mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses.

1991 • 369 citations

Basophil influx occurs after nasal antigen challenge: Effects of topical corticosteroid pretreatment

1988 • 305 citations

Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils.

1991 • 259 citations

Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils

1992 • 227 citations

Interleukin 3-dependent mediator release in basophils triggered by C5a.

1989 • 207 citations

High affinity human IgE receptor (Fc epsilon RI). Analysis of functional domains of the alpha-subunit with monoclonal antibodies

1991 • 197 citations

Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils

1992 • 184 citations

Simultaneous production of interleukin 2, interleukin 4 and interferon‐γ by activated human blood lymphocytes

1990 • 165 citations

Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines.

1990 • 149 citations

Human bone marrow non-B, non-T cells produce interleukin 4 in response to cross-linkage of Fc epsilon and Fc gamma receptors.

1991 • 99 citations

IL-4 release by human leukemic and activated normal basophils.

1993 • 75 citations

Internalization of ige receptors on rat basophilic leukemic cells by phorbol ester. comparison with endocytosis induced by receptor aggregation

1989 • 26 citations

Transfected Chinese hamster ovary cells as model system for cytokine immunocytochemistry and in situ hybridisation.

1993 • 1 citations