A review of the genotoxicity of food, drug and cosmetic colours and other azo, triphenylmethane and xanthene dyes

Personal Communication

2014 • 3,860 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Thomas, Springfield, Illinois

1965 • 2,935 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Chemical Mutagens. Principles and Methods for Their Detection.

1974 • 1,473 citations

Estimation of toxic hazard—A decision tree approach

1976 • 1,411 citations

Chemical induction of sperm abnormalities in mice.

1975 • 871 citations

Short-term tests for carcinogens and mutagens

1979 • 693 citations

The chemistry of the nitro and nitroso groups

1969 • 619 citations

A Study on the Fate of Curcumin in the Rat

1978 • 610 citations

A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds

1980 • 585 citations

Progress in Genetic Toxicology

1978 • 581 citations

Hair dyes are mutagenic: identification of a variety of mutagenic ingredients.

1975 • 474 citations

Chromosome tests with 134 compounds on Chinese hamster cells in vitro — A screening for chemical carcinogens

1977 • 445 citations

Molecular and environmental aspects of mutagenesis

1976 • 444 citations

An evaluation of 6 short-term tests for detecting organic chemical carcinogens

1978 • 427 citations

Tumours Of The Urinary Bladder in Workmen Engaged in the Manufacture and Use Of Certain Dyestuff Intermediates In The British Chemical Industry. Part I. The Role Of Aniline, Benzidine, Alpha-Naphthylamine, And Beta-Naphthylamine

1954 • 425 citations

The Chemistry of the Hydrazo, Azo and Azoxy Groups

1975 • 420 citations

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

1979 • 412 citations

Mutagenicity of carcinogenic azo dyes and their derivatives

1975 • 399 citations

Repair Replication of Mammalian Cell DNA: Effects of Compounds That Inhibit DNA Synthesis or Dark Repair

1969 • 355 citations

Survey of Compounds Which Have Been Tested for Carcinogenic Activity

1942 • 354 citations

The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1

2015 • 349 citations

Morphological transformation of early passage Golden Syrian Hamster embryo cells derived from cryopreserved primary cultures as a reliable in vitro bioassay for identifying diverse carcinogens

1977 • 326 citations

The Carcinogenic Aminoazo Dyes

1953 • 325 citations

In vitro and host-mediated “rec-assay” procedures for screening chemical mutagens; and phloxine, a mutagenic red dye detected

1972 • 301 citations

Reduction of azo dyes by intestinal anaerobes

1978 • 271 citations

Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test

1979 • 238 citations

Mutagenicity of metronidazole: Activation by mammalian liver microsomes

1975 • 237 citations

The metabolism of azo compounds: a review of the literature

1970 • 228 citations

Chemical Mutagens in the Human Environment

1968 • 224 citations

Fundamentals of Cancer Prevention

2013 • 222 citations

The micronucleus test as part of a short-term mutagenicity test program for the prediction of carcinogenicity evaluated by 143 agents tested

1980 • 221 citations

Testing of some azo dyes and their reduction products for mutagenicity using Salmonella typhimurium TA 1538

1977 • 218 citations

The Primary Aromatic Amines: Their Biological Properties and Structure-Activity Relationships

1979 • 217 citations

Mutagenesis by 9,10-anthraquinone derivatives and related compounds in Salmonella typhimurium

1976 • 215 citations

SPECIAL MICROBIOLOGICAL SYSTEMS. II. OBSERVATIONS ON CHEMICAL MUTAGENESIS IN MICROORGANISMS*

1958 • 202 citations

A new theory of carcinogenesis

1979 • 201 citations

Prophage lambda induction of Escherichia coli K12 envA uvrB: a highly sensitive test for potential carcinogens.

1976 • 200 citations

The Molecular Biology of Photodynamic Action: Sensitized Photoautoxidations in Biological Systems ,

1969 • 197 citations

Evaluation of the Mutagenicity and DNA-Modifying Activity of Carcinogens and Noncarcinogens in Microbial Systems<xref ref-type="fn" rid="FN2">2</xref>

1979 • 195 citations

Evaluation of the carcinogenicity of chemicals: a review of the Monograph Program of the International Agency for Research on Cancer (1971 to 1977).

1978 • 186 citations

Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora.

1980 • 179 citations

In Vitro Mutagenicity Assays of Chemical Carcinogens and Related Compounds With <italic>Salmonella typhimurium</italic><xref ref-type="fn" rid="FN2">2</xref>

1979 • 169 citations

IS p-AMINOBENZENESULPHONAMIDE THE ACTIVE AGENT IN PRONTOSIL THERAPY ?

1937 • 156 citations

Health services in France.

1949 • 154 citations

Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity.

1978 • 153 citations

Cytogenetic toxicity of gentian violet and crystal violet on mammalian cells in vitro

1978 • 151 citations

Screening of Environmental Chemical Mutagens by the Rec-Assay System with Bacillus subtilis

1980 • 149 citations

Metabolic Reduction of Benzidine Azo Dyes to Benzidine in the Rhesus Monkey2

1975 • 148 citations

Demonstration of mutagenicity of aniline and o-toluidine by norharman.

1977 • 144 citations

The Function of Drosophila in Genetic Toxicology Testing

1976 • 139 citations

THE REDUCTIVE CLEAVAGE OF 4-DIMETHYLAMINOAZOBENZENE BY RAT LIVER: THE INTRACELLULAR DISTRIBUTION OF THE ENZYME SYSTEM AND ITS REQUIREMENT FOR TRIPHOSPHOPYRIDINE NUCLEOTIDE

1949 • 137 citations

Chemical carcinogens: ACS monograph 173

1977 • 135 citations

The development of carcinoma in liver of rats treated with m-toluylenediamine and the synergistic and antagonistic effects with other chemicals.

1969 • 135 citations

Studies on the mechanism of action of mammalian hepatic azoreductase—I

1967 • 134 citations

THE INFLUENCE OF ENTEROHEPATIC CIRCULATION ON TOXICITY OF DRUGS*

1965 • 128 citations

The excretion and metabolism of edible food colors

1962 • 123 citations

The evaluation of sixteen carcinogens in the rat using the micronucleus test

1978 • 120 citations

Survey of Compounds Which Have Been Tested for Carcinogenic Activity

1953 • 120 citations

Mutagenicity testing of certified food colors and related azo, xanthene and triphenylmethane dyes with the Salmonella/microsome system

1978 • 119 citations

Microbial Ecology: A Conceptual Approach

1979 • 117 citations

PHOTODYNAMIC INACTIVATION OF E. COLI BY ROSE BENGAL IMMOBILIZED ON POLYSTYRENE BEADS

1978 • 115 citations

The absorption, fate and excretion in rats of the water-soluble azo dyes, FD&C Red No. 2, FD&C Red No. 4, and FD&C Yellow No. 6.

1962 • 111 citations

Poly(vinylamine hydrochloride). Synthesis and utilization for the preparation of water-soluble polymeric dyes

1976 • 111 citations

Mutagenicity of anthraquinone and benzanthrone derivatives in the salmonella/microsome test: Activation of anthraquinone glycosides by enzymic extracts of rat cecal bacteria

1979 • 111 citations

Composition, treatment efficiency, and environmental significance of dye manufacturing plant effluents

1977 • 107 citations

The role of metabolism in chemical mutagenesis and chemical carcinogenesis

1980 • 102 citations

Mutagenic activity of rhodamine dyes and their impurities as detected by mutation induction in Salmonella and DNA damage in Chinese hamster ovary cells.

1979 • 102 citations

Testing of some benzidine analogues for microsomal activation to bacterial mutagens

1975 • 100 citations

Subcutaneous sarcoma as an index of carcinogenic potency

1966 • 99 citations

Aromatic amines in and near the Buffalo River

1980 • 98 citations

Bacterial mutagenicity and mammalian cell DNA damage by several substituted anilines

1980 • 96 citations

Reduction of water-soluble azo dyes by intestinal bacteria

1967 • 93 citations

Screening of food dyes for genotoxic activity

1980 • 91 citations

Mechanisms of Chemical Carcinogenesis

1978 • 91 citations

Azo reduction of trypan blue to a known carcinogen by a cell-free extract of a human intestinal anaerobe

1978 • 91 citations

The relationship between in vitro transformation and tumor formation in vivo

1976 • 90 citations

The detection of carcinogen-induced sperm head abnormalities in mice

1980 • 88 citations

Non-disjunction and crossing-over induced by pharmaceutical drugs in Aspergillus nidulans

1974 • 87 citations

Testing of Twenty-one Environmental Aromatic Amines or Derivatives for Long- Term Toxicity or Carcinogenicity

1979 • 87 citations

Determining the DNA-Modifying Activity of Chemicals Using DNA-Polymerase-Deficient Escherichia coli

1980 • 87 citations

Transformation of Cell Cultures as an Indication of the Carcinogenic Potential of Chemicals2

1973 • 85 citations

Mutagenic Activity of Chemical Carcinogens and Related Compounds in the Intraperitoneal Host-Mediated Assay<xref ref-type="fn" rid="FN2">2</xref>

1979 • 84 citations

MUTATIONS IN ESCHERICHIA COLI INDUCED BY CHEMICAL AGENTS

1947 • 83 citations

Detection of metabolic carcinogen intermediates in urine of carcinogen-fed rats by means of bacterial mutagenesis

1974 • 83 citations

Detection of mutagenic derivatives of cyclophosphamide and a variety of other mutagens in a “microtitre”R fluctuation test, without microsomal activation

1978 • 83 citations

In Vitro Studies of Effects of Light and Riboflavin on DNA and HeLa Cells

1975 • 82 citations

The three-tier approach to mt1tagenicity screening and the concept of radiation-equivalent dose

1974 • 81 citations

Carcinogenesis in vitro

1975 • 79 citations

Resistance to Deformation of Axial Structures in Living Guinea-Pig Spermatozoa

1959 • 78 citations

Further studies on the carcinogenicity of dyes related to 4-dimethylaminoazobenzene; the requirement for an unsubstituted 2-position.

1957 • 77 citations

Genetic effects of turmeric and curcumin in mice and rats

1980 • 77 citations

Frameshift Mutagenicity of Certain Naturally Occurring Phenolic Compounds in the ‘Salmonella/Microsome’ Test: Activation of Anthraquinone and Flavonol Glycosides by Gut Bacterial Enzymes

1977 • 77 citations

Rat liver cytosolic azoreductase. Electron transport properties and the mechanism of dicumarol inhibition of the purified enzyme.

1979 • 76 citations

Studies on the clastogenic effects of biologic stains and dyes

1979 • 74 citations

Further study of the genetic toxicity of gentian violet

1979 • 74 citations

Role of gut bacterial flora in nutrition and health: A review of recent advances in bacteriological techniques, metabolism, and factors affecting flora composition

1977 • 74 citations

Some Molecular Parameters Influencing Rate of Reduction of Azo Compounds by Intestinal Microflora

1971 • 72 citations

Examination of the potential mutagenicity of hair dye constituents using the micronucleus test

1977 • 71 citations

Characterization of DNA adducts of the carcinogen N-methyl-4-aminoazobenzene in vitro and in vivo

1980 • 70 citations

Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides, and disulfides

1979 • 66 citations

Metabolism Studies of an Azo Dye and Pigment in the Hamster Based on Analysis of the Urine for Potentially Carcinogenic Aromatic Amine Metabolites

1980 • 65 citations

Toxicity of methylimidazoles

1969 • 64 citations

In vitro and in vivo indications of the carcinogenicity and toxicity of food dyes

1978 • 64 citations

Metabolism and excretion patterns of fluorescein and certain halogenated fluorescein dyes in rats.

1962 • 63 citations

The Metabolism of Dimethylaminoazobenzene (Butter Yellow) in Rats

1942 • 62 citations

Metabolism of aniline in rats, pigs and sheep.

1978 • 62 citations

Current Aspects Of Food Colorants

1978 • 62 citations

Food, drug, and cosmetic dyes: biological effects related to lipid solubility.

1977 • 60 citations

Color chemistry and the environment

1977 • 60 citations

Mutagenicity of some congeners of benzidine in the salmonella typhimurium assay system

1978 • 59 citations

Effects of food seasonings on the cell cycle and chromosome morphology of mammalian cells in vitro with special reference to turmeric

1976 • 58 citations

Experimental study of xanthene dyes as carcinogenic agents.

1956 • 58 citations

Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test

1979 • 58 citations

Mechanisms of Azo Reduction by StreptococcusfaecalisI. Optimization of Assay Conditions

1971 • 56 citations

Structure-mutagenicity relationships of N-oxidized derivatives of aniline, o-toluidine, 2'-methyl-4-aminobiphenyl, and 3,2'-dimethyl-4-aminobiphenyl

1979 • 54 citations

Environmental Carcinogenesis: occurrence, Risk Evaluation and Mechanisms

1980 • 54 citations

Initial National Cancer Institute Studies on Mutagenesis as a Prescreen for Chemical Carcinogens: An Appraisal

1979 • 53 citations

Mutagenicity of four hair dyes in Drosophila melanogaster

1977 • 52 citations

The mutagenicity of methyl orange and metabolites produced by intestinal anaerobes

1978 • 51 citations

Studies on the metabolites of fluorescein in rabbit and human urine.

1980 • 51 citations

Mutagenicity testing of some approved food additives with the Salmonella/microsome assay.

1980 • 50 citations

The metabolism of azo compounds

1944 • 49 citations

Microbial assays for mutagenicity: A modified liquid culture method compared with the agar plate system for precision and sensitivity

1978 • 49 citations

Mutagenicity test of dyes used in cosmetics with the Salmonella/mammalian-microsome test

1979 • 49 citations

Mutagenicity of metabolites of carcinogenic aminoazo dyes

1979 • 48 citations

Fluorescence properties of free and protein bound fluorescein dyes. I. Macrospectrofluorometric measurements.

1978 • 47 citations

Photodynamic inactivation of transforming principle

1960 • 47 citations

Mutagenicity of arylmethane dyes in salmonella

1981 • 47 citations

The Excretion of Some Azo Dyes in Rat Bile

1961 • 47 citations

Trace Analysis of Potentially Carcinogenic Metabolites of an Azo Dye and Pigment in Hamster And Human Urine as Determined by Two Chromatographic Procedures

1980 • 46 citations

Genetic effects of chlorinated anilines and azobenzenes onSalmonella typhimurium

1980 • 45 citations

Studies in detoxication. 39. Nitro compounds. (a) The metabolism of o-, m- and p-nitrophenols in the rabbit. (b) The glucuronides of the mononitrophenols and observations on the anomalous optical rotations of triacetyl β-o-nitrophenylglucuronide and its methyl ester

1951 • 45 citations

Long-term toxicity study in the rat on a caramel produced by the ‘half open-half closed pan’ ammonia process

1977 • 45 citations

In vitro evaluation of some derivatives of the carcinogen butter yellow: implications for environmental screening

1978 • 45 citations

Collaborative Studies on the Salmonella/Microsome Mutagenicity Assay

1979 • 44 citations

A Review of the Specifications and Toxicity of Synthetic Food Colors Permitted in Canada

1979 • 43 citations

Reduction of sulphonated water-soluble azo dyes by micro-organisms from human faeces

1980 • 43 citations

Evaluation of the genotoxicity of some natural food colours using bacterial assays

1981 • 43 citations

Mutagenic Activity of Tryptophan Metabolites Produced by Rat Intestinal Microflora23

1976 • 42 citations

Induction of gene conversion in diploid yeast by chemicals: Correlation with mutagenic action and its relevance in genotoxicity screening

1979 • 41 citations

The mutagenicity of some of the proposed metabolites of direct black 38 and pigment yellow 12 IN THE Salmonella typhimurium assay system

1979 • 41 citations

Food colours — harmless aesthetics or epicurean luxuries?

1975 • 41 citations

Measurement of DNA-excision repair in suspensions of freshly isolated rat hepatocytes after exposure to some carcinogenic compounds

1979 • 41 citations

N-hydroxy metabolites of 2-acetylaminophenanthrene and 7-fluoro-2-acetylaminofluorene as proximate carcinogens in the rat.

1966 • 41 citations

Possible hazard in use of gentian violet.

1971 • 39 citations

Toxicology of Food Colors

1974 • 38 citations

Comutagenicity, competitive enzyme substrates, and in vitro carcinogenicity assays

1978 • 38 citations

Intestinal Absorption of Polymeric Derivatives of the Food Dyes Sunset Yellow and Tartrazine in Rats

1977 • 37 citations

Testing of some permitted food colours for the induction of gene conversion in diploid yeast

1979 • 37 citations

The use of yeast cultures for the detection of environmental mutagens using a fluctuation test

1977 • 37 citations

Mutagenicity of the food colour brown FK and constituents in Salmonella typhimurium

1976 • 37 citations

The effects of Rhodamine B on the chromosomes of Muntiacus muntjac

1981 • 36 citations

Mutagenicity of 19 major graphic arts and printing dyes

1978 • 36 citations

Activation of a procarcinogen to a mutagen by cell-free extracts of anaerobic bacteria

1977 • 36 citations

Studies on the genotoxicity of some fluorescein dyes

1981 • 36 citations

Absorption and excretion of certain triphenylmethane colors in rats and dogs.

1955 • 35 citations

Mutations and loss of transforming activity of Bacillus subtilis DNA after reaction with esters of carcinogenic N-hydroxy aromatic amides.

1970 • 35 citations

Absorption, excretion, metabolism and cardiovascular effects of beetroot extract in the rat

1980 • 35 citations

Acute and short-term toxicity studies on erythrosine BS in rodents

1976 • 35 citations

Mutagenicity of Benzidine and Related Compounds Employed in the Detection of Hemoglobin

1977 • 34 citations

N-Oxidation of Certain Aromatic Amines, Acetamides, and Nitro Compounds by Monkeys and Dogs2

1973 • 34 citations

Mutations by Photodynamic Action in Bacterium prodigiosum

1949 • 34 citations

Mutagenicity testing of some drug and cosmetic dye lakes with the Salmonella/mammalian microsome assay

1979 • 34 citations

Effect of amaranth, Ponceau 4R and/or vitamin A on enzyme activities of the rat liver

1978 • 32 citations

Selection of Carcinogens and Related Compounds Tested for Mutagenic Activity

1979 • 31 citations

Mutagenic Potential of the Condiments, Ginger and Turmeric

1976 • 31 citations

Studies in vitro to discern the structural requirements for carcinogenicity in analogues of the carcinogen 4-dimethylaminoazobenzene (butter yellow)

1980 • 30 citations

Studies on reduction of azo-linkages in human placental homogenates

1968 • 30 citations

Some properties of a nitrite reductase from Pseudomonas denitrificans

1968 • 30 citations

Synthesis of 14C-labelled FD & C blue no. 1 (brilliant blue FCF) and its intestinal absorption and metabolic fate in rats

1980 • 29 citations

Metabolic aspects of food safety

1971 • 29 citations

Mutagenicity of 3'-methyl-N, N-dimethyl-4-amino azobenzene metabolites and related compounds

1980 • 28 citations

Studies of the metabolism of Rhodamine B

1961 • 28 citations

Mutagenicity of hair dye components relative to the carcinogen benzidine in Drosophila melanogaster

1977 • 27 citations

On the structure of carminic acid and carmine

1971 • 27 citations

The metabolic disposition of 14C-labelled green S and brilliant blue FCF in the rat, mouse and guinea-pig

1980 • 26 citations

The N-hydroxy metabolites of N-methyl-4-aminoazobenzene and related dyes as proximate carcinogens in the rat and mouse.

1979 • 26 citations

The Mutagenic Activity of Dyes in Drosophila melanogaster

1953 • 26 citations

Genotoxicity of the food colours red 2G and brown FK in bacterial systems; use of structurally-related dyes and azo-reduction

1980 • 26 citations

Association of salmonella mutants with germfree rats: site specific model to detect carcinogens as mutagens.

1975 • 25 citations

Photodynamic action of fluorescein dyes in DNA-damage and in vitro inactivation of transforming DNA in bacteria

1978 • 25 citations

Color Additives: Botched Experiment Leads to Banning of Red Dye No. 2

1976 • 25 citations

Measurement of drug-metabolizing systems in Salmonella typhimurium strains G46, TA1535, TA100, TA1538 and TA98

1980 • 25 citations

An evaluation of the prophage λ induction (inductest) for the detection of potential carcinogens

1978 • 25 citations

Reduction of Sulphonated Water‐soluble Azo Dyes by Caecal Microorganisms from the Rat

1976 • 24 citations

An evaluation of the mutagenicity of the cutting oil preservative Grotan BK

1976 • 24 citations

Mutationsausl�sung bei Bacterum prodigiosum durch sichtbares Licht nach Vitalf�rbung mit Erythrosin

1950 • 24 citations

Mutagenicity of 8-hydroxyquinoline and related compounds in the salmonella typhimurium bioassay

1976 • 23 citations

The fate of FD&C Red No. 2 and its metabolite, naphthionic acid, after different routes of administration in the rat

1976 • 23 citations

Sister-chromatid exchange induction by metabolically activated retinoids in human diploid fibroblast cultures

1980 • 22 citations

History of Chemical Carcinogenesis: Some Prospective Remarks

2015 • 22 citations

Drugs containing tartrazine dye

1976 • 22 citations

A review of the metabolism of xenobiotics by microorganisms with relation to short-term test systems for environmental carcinogens

1978 • 21 citations

THE INFLUENCE OF DIET ON THE RIBOFLAVIN CONTENT AND THE ABILITY OF RAT LIVER SLICES TO DESTROY THE CARCINOGEN N,N-DIMETHYL-p-AMINOAZOBENZENE

1949 • 21 citations

Metabolites of p-Aminobenzoic Acid. IV. Structure of “Metabolite I” and Aryl Hydroxylation Prior Hydroxymethylation of the Benzene Ring^*

1964 • 21 citations

The Need for Both in Vitro and in Vivo Systems in Mutagenicity Screening

1980 • 21 citations

Uptake, distribution and metabolism of [14C]amaranth in the female rat

1979 • 21 citations

Genetic properties of substituted derivatives of N‐methyl‐4‐aminoazobenzene in relation to azo‐dye carcinogenesis

1972 • 20 citations

Studies on the macromolecular binding of benzidine

1980 • 20 citations

Suppression of naphthylamine mutagenicity by Amaranth

1979 • 20 citations

Myotoxicity of amine metabolites from brown FK

1970 • 20 citations

The effect of the administration of n,n-dimethyl-4-aminoazobenzene (dab) on the activity of dab-reductase and nadph-cytochrome c reductase

1970 • 19 citations

Carcinogenic properties of the red food dyes Amaranth, Ponceau SX and Ponceau 4R.

1970 • 19 citations

Methodology for the testing of food dyes for genotoxic activity: Experiments with red 2G (C.I. 18050)

1979 • 19 citations

Biochemistry and Pharmacology of the Nitro and Nitroso Groups

2010 • 18 citations

Toxicologic and Cancerogenic Evaluation of Chemicals Used in the Graphic Arts Industries

1976 • 18 citations

Formation of 3-(glutathion-S-yl)-N-methyl-4-aminoazobenzene and inhibition of aminoazo dye-nucleic acid binding in vitro by reaction of glutathione with metabolically-generated N-methyl-4-aminoazobenzene-N-sulfate

1980 • 17 citations

Comparative Results of Short-Term in Vitro and in Vivo Mutagenicity Tests Obtained with Selected Environmental Chemicals

1980 • 17 citations

Problems confronted and lessons learnt in the safety evaluation of brown FK

1968 • 17 citations

Detection of carcinogenicity of color cosmetics in bacterial test systems

1976 • 17 citations

Xenobiotic-metabolising cytochromes P-450 from micro-organisms

1980 • 17 citations

Evaluation of benzidine by the micronucleus test

1979 • 17 citations

Trypan Blue-induced Deletions in Duplication Strains of Aspergillus nidulans

1970 • 17 citations

The influence of gut micro-organisms on the metabolism of drugs and food additives

1973 • 16 citations

Lebensmittelzusatzstoffe und mutagene Wirkung VI. Mitteitung Pr�fung der in Westdeutschland zugelassenenl und urspr�nglich vorgeschlagenen2 Lebensmittelfarbstoffe ant mutagene Wirkung an Escherichia coli

1960 • 16 citations

CARCINOGENIC SYNERGISM AND ITS REFLECTION IN VITRO

1980 • 14 citations

Gut microflora interactions with two experimental polymeric food additives in the rat

1978 • 14 citations

The application of short-term microbial mutagenicity tests in the identification and development of non-toxic, non-absorbable food additives

1978 • 13 citations

�ber die Reduktion von Azofarbstoffen, insbesondere von Azorubin durch Milchs�urebakterlen

1955 • 13 citations

Analysis, Purification and Stability: Requirements for a Metabolism Study of an Azo Dye and Pigment

1980 • 13 citations

Studies of Brown FK. I. Composition and synthesis of components

1967 • 13 citations

Nachweis von durch Säuerung entfärbten künstlichen Eigelbfarbstoffen in Milchspeiseeis

1937 • 13 citations

Counteracting effect of eosin and related dyestuffs on the production of respiration-deficient mutants in yeast by 4-nitroquinoline 1-oxide

1976 • 12 citations

Mutagenic activity of anthraquinone derivatives used as dyes in a textile factory.

1975 • 12 citations

The metabolism and excretion of black PN in the rat and man

1970 • 12 citations

Nitroxide radicals generated from carcinogenic aminoazo dyes during their metabolism in vivo and in enzymatic system in vitro

1979 • 12 citations

Selection of Carcinogens and Related Compounds Tested for Mutagenic Activity

1980 • 12 citations

Mutagenicity in Salmonella of Rhodamine WT, a dye used in Environmental water-tracing studies

1979 • 12 citations

Comparative mutagenicity of two triarylmethane food dyes in salmonella, saccharomyces and drosophila

1981 • 12 citations

Mutagenesis in cultured human diploid cells. IV. Induction of 8-azaguanine resistant mutations by phloxine, a mutagenic red dye.

1975 • 11 citations

Studies on the Metabolism of Orange RN in the Pig

1976 • 11 citations

An improved method for detecting mutagens

1978 • 11 citations

The metabolism of FD&C Red No. 1. I. The fate of 2,4-meta-xylidine in rats.

1961 • 11 citations

Über die Biologische Spaltung von Azofarbstoffen Durch Hefe

1942 • 10 citations

Mutagenicity in Salmonella of fluorescent dye tablets used in water tracing

1980 • 10 citations

Potential role of non-nutritive food additives and contaminants as environmental carcinogens.

1956 • 10 citations

The behaviour of Evans blue (azo-dye T-1824) in the body after intravenous injection.

1967 • 10 citations

Studies on the fate of quinoline yellow in the rat

1979 • 9 citations

Mutagenesis in cultured human diploid cells

1975 • 9 citations

Selection of species for cancer bioassay for naphthylamine-containing food colours on the basis of tissue-mediated mutagenicity

1978 • 9 citations

Carcinogenicity Testing: principles and Problems

1978 • 9 citations

The potential role of nonnutritive food additives and contaminants as environmental carcinogens.

1957 • 8 citations

Carcinogenic azo dyes. XI. Analysis of biliary and urinary metabolites of 3'-methyl-4-(methylamino)azobenzene in rat.

1979 • 8 citations

Comparison of the biological values of food protein and an equivalent mixture of amino acids.

1968 • 8 citations

Safety and Toxicological Aspects in Handling Chemicals in the Colour‐using Industry

1976 • 8 citations

Mutagenicity studies of R-amino salt, a metabolite of amaranth (FD & C Red No. 2), in mouse lymphoma cells heterozygous at the thymidine kinase locus and in the rat dominant lethal test

1979 • 8 citations

Intestinal absorption of two potential polymeric food additives in man

1979 • 8 citations

Enzyme Induction in Microbial Organisms

1975 • 7 citations

Separation of non-dye components of Brown FK by high-performance liquid chromatography

1978 • 7 citations

Mutagenicity of azo-compounds — Improved method for detecting their mutagenicities by the Salmonella mutation test

1978 • 7 citations

Effects of metanil yellow on human leucocyte chromosomes in vitro.

1978 • 6 citations

The Coloration of Food

1973 • 5 citations

On the mutagenicity of some azo-dyes

1978 • 4 citations

Carcinogenic azo dyes. XII. Detection of new metabolites of aminoazo dyes by rat liver.

1979 • 3 citations

Point mutations induced by pharmaceutical drugs

1975 • 3 citations

Effect of intratesticular administration of metanil yellow in rats.

1972 • 3 citations

Carcinogenicity of Cosmetic Materials

1979 • 2 citations

Correlation between azo reduction and formation in vitro of DMA-bound DAB metabolites in liver microsomes from rats fed on carcinogenic or normal diets

1974 • 2 citations

Potential Role of Non-Nutritive Food Additives and Contaminants as Environmental Carcinogens. (Special Article.).

1956 • 2 citations

Hepatic nodules and tumours in the rat

1978 • 1 citations

Transport and Fate of Substances Absorbed in the Gastrointestinal Tract with Special Reference to Blood and Tissue Levels

1970 • 1 citations

In vitro effect of L-tryptophan and its metabolites on dimethylaminoazobenzene reductase activity of rat liver

1979 • 1 citations

Deleted Work

1955 • 0 citations