Determining the DNA-Modifying Activity of Chemicals Using DNA-Polymerase-Deficient Escherichia coli

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 749 citations

STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI

1954 • 406 citations

Genetic Analysis of an E. coli Strain with a Mutation affecting DNA Polymerase

1969 • 223 citations

Rapid detection of mutagens and carcinogens.

1971 • 218 citations

Evaluation of the Mutagenicity and DNA-Modifying Activity of Carcinogens and Noncarcinogens in Microbial Systems<xref ref-type="fn" rid="FN2">2</xref>

1979 • 195 citations

Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures

1979 • 175 citations

In Vitro Mutagenicity Assays of Chemical Carcinogens and Related Compounds With <italic>Salmonella typhimurium</italic><xref ref-type="fn" rid="FN2">2</xref>

1979 • 169 citations

DNA Polymerase Required for Rapid Repair of X-ray—Induced DNA Strand Breaks in vivo

1971 • 160 citations

Comparative analysis of deletion and base-change mutabilities of Escherichia coli B strains differing in DNA repair capacity (Wild-type, uvra-, pola-, reca-) by various mutagens

1975 • 152 citations

Repair of damage induced by ultraviolet light in DNA polymerase-defective Escherichia coli cells

1971 • 139 citations

Does carcinogenic potency correlate with mutagenic potency in the Ames assay?

1978 • 135 citations

The mutagenicity and DNA-modifying effect of haloalkanes.

1974 • 130 citations

Studies with hydroxyurea

1966 • 123 citations

Evaluation of a DNA polymerase-deficient mutant of E. coli for the rapid detection of carcinogens

1976 • 100 citations

Silver Sulfadiazine: Effect on the Growth and Metabolism of Bacteria

1972 • 89 citations

Evaluation of the mutagenicity of compounds of known carcinogenicity, belonging to the benz[a]anthracene, chrysene, and cyclopenta[a]phenanthrene series, using Ames's test.

1976 • 84 citations

Does carcinogenic potency correlate with mutagenic potency in the Ames assay?

1978 • 79 citations

Mutagenicity and DNA- modifying activity: A comparison of two microbial assays

1976 • 77 citations

Ultraviolet- and X-Ray-Induced Responses of a Deoxyribonucleic Acid Polymerase-Deficient Mutant of Escherichia coli

1971 • 71 citations

Genetic activity of 1,2-dibromo-3-chloropropane, a widely-used fumigant

1975 • 67 citations

Mutagenicity of sodium hypochlorite for Salmonella typhimurium

1975 • 65 citations

Mutagenicity of Halogenated Alkanes and Their Derivatives

1977 • 62 citations

The quantitative microsomal mutagenesis assay method

1975 • 61 citations

Nalidixic Acid and the Metabolism of Escherichia coli

1970 • 59 citations

2-haloethanols: Mutagenicity and reactivity with DNA

1974 • 48 citations

Possible hazard in use of gentian violet.

1971 • 39 citations

Sensitivity of repair-deficient mutants and similar mutants to 4-nitroquinoline 1-oxide, 4-nitropyridine 1-oxide, and their derivatives.

1972 • 38 citations

Sodium hypochlorite and sodium perborate: preferential inhibitors of DNA polymerase-deficient bacteria

1973 • 35 citations

Genetic activity of allyl chloride

1978 • 33 citations

Mutagenicity of ethylene chlorohydrin. Degradation product present in foods exposed to ethylene oxide

1974 • 27 citations

Aspects of Microbiology in Cancer Research

1973 • 26 citations

Trial of a bacterial screening system for rapid detection of mutagens and carcinogens.

1974 • 26 citations

Formaldehyde as a possible carcinogen

1972 • 21 citations

Genetic Effects of Povidone‐Iodine

1975 • 21 citations

Biological and metabolic effects of nitro-somethylurea and nitrosomethylurethan.

1968 • 18 citations

Unusual growth properties of a bacterial strain lacking DNA polymerase

1971 • 18 citations

X-Irradiation sensitivity in Escherichia coli defective in DNA replication

1971 • 18 citations

HYDRAZINE ANTIDEPRESSANTS AND ISONIAZID : POTENTIAL CARCINOGENS

1971 • 17 citations

Preferential effect of dichlorvos (Vapona) on bacteria deficient in DNA polymerase.

1973 • 16 citations

The concentration of 67Ga and 45Ca in the lactating mammary gland and its relevance to the tumor uptake of 67Ga citrate.

1976 • 16 citations

Recovery from N -Hydroxyurethan-Induced Death

1971 • 15 citations

“Reversion” of DNA polymerase-deficient Escherichia coli

1971 • 15 citations

The use of Microbial Assay Systems in the Detection of Environmental Mutagens in Complex Mixtures

1978 • 13 citations

Simple Correlation and Multiple Regression Among Leaf Characteristics, Smoke Components, and Biological Responses of Bright Tobaccos

1977 • 12 citations

Hydroxylamine-O-sulfonic acid: In vitro and possible in vivo reaction with DNA

1973 • 10 citations

Miracil D: Inhibition of Deoxyribonucleic Acid Polymerase-Deficient Escherichia coli

1973 • 10 citations

Picrolonic acid: a novel frameshift mutagen

1975 • 10 citations

Effects of Acridine Orange on the Growth of Escherichia coli

1972 • 9 citations

Studies with hydroxyurea

1971 • 9 citations

Studies on the Detection of Carcinogens Using a Mammalian Cell Transformation Assay with Liver Homogenate Activation

1980 • 9 citations

Hydroxyurea and cell death.

1972 • 5 citations

Super-sensitive DNA-repair test-liquid for confirming DNA-damagicity of mutagens

1978 • 4 citations